Sorin Bogdan Motoi

Dr. Sorin Bogdan Motoi

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Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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12 August 2021 in Applied Sciences
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CFCosmin Ioan Faur
Cosmin Ioan Faur
DPDaniel Laurentiu Pop
Daniel Laurentiu Pop
Ahmed Abu-AwwadAhmed Abu-Awwad
Ahmed Abu-Awwad
CZCarmen Zamfir
Carmen Zamfir
RFRoxana Folescu
Roxana Folescu
AUAna-Maria Ungureanu
Ana-Maria Ungureanu
Synovial sarcoma (SS) is a rare and highly malignant tumor and a type of soft tissue sarcoma (STS), for which survival has not improved significantly in recent years. Synovial sarcomas occur mostly in adolescents and young adults (15–35 years old), usually affecting the deep soft tissues near the large joints of the extremities, with males being at a slightly higher risk. Despite its name, synovial sarcoma is neither related to the synovial tissues that are a part of the joints, i.e., the synovium, nor does it express synovial markers; however, the periarticular synovial sarcomas can spread as a secondary tumor to the joint capsule. SS was initially described as a biphasic neoplasm comprising of both epithelial and uniform spindle cell components. Synovial sarcoma is characterized by the presence of the pathognomonic t (X; 18) (p11.2; q11.2) translocation, involving a fusion of the SS18 (formerly SYT) gene on chromosome 18 to one of the synovial sarcoma X (SSX) genes on chromosome X (usually SSX1 or SSX2), which is seen in more than 90% of SSs and results in the formation of SS18-SSX fusion oncogenes.

25 September 2023 in Medicina
Verified
Journal Article
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ESEugen Horatiu Stefanescu
Eugen Horatiu Stefanescu
Nicolae Constantin BalicaNicolae Constantin Balica
Nicolae Constantin Balica
SMSorin Bogdan Motoi
Sorin Bogdan Motoi
GLGRIGORITA LAURA
GRIGORITA LAURA
MGMadalina Georgescu
Madalina Georgescu
GIGheorghe Iovanescu
Gheorghe Iovanescu
Background and Objectives: The diagnosis of cholesteatoma is usually clinic, and the only efficient treatment is surgical. High-resolution computed tomography (HRCT) is not considered absolutely necessary for the management of an uncomplicated cholesteatoma, but unsuspected situations from a clinical point of view can be discovered using the scans, warning the surgeon. Our objective is to compare HRCT scan information with intraoperative findings in patients with cholesteatoma and analyze the usefulness of a preoperative HRCT scan from a surgical point of view. Materials and Methods: This is a prospective descriptive study conducted in the Department of Otolaryngology, Victor Babes University of Medicine and Pharmacy Timisoara, Romania, from May 2021 to April 2022. It was carried out on 46 patients with a clinical diagnosis of cholesteatoma who were consequently operated on in our department. All patients received full clinical and audiological examinations. In all cases, an HRCT scan was performed preoperatively as a mandatory investigation. Preoperative HRCT scans were analyzed, and their findings were compared to the intraoperative notes. The two sets of observations were analyzed using standard statistical methods. Results: Extensive cholesteatoma was the most common type of disease, involving 46% of the patients, followed by pars flaccida cholesteatoma (35%) and pars tensa cholesteatoma (19%). Eroded scutum was the most frequent lesion involving 70% of the patients, followed by incus erosion (67%). Comparison of the HRCT and intraoperative findings revealed a very good correlation for tegmen tympani erosion, sigmoid plate erosion, scutum and malleus erosion, and a moderate-to-good correlation for lateral semicircular canal erosion, incus and stapes erosion, and fallopian canal erosion. Conclusions: HRCT is a valuable tool in the preoperative assessment of cholesteatoma, helping in making surgical decisions. It can accurately predict the extent of disease and is helpful for detecting unapparent dangerous situations. However, it is not very accurate in detecting fallopian canal and stapes erosion.

5 September 2023 in Preprints.org
Verified
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ESEugen Horatiu Stefanescu
Eugen Horatiu Stefanescu
Nicolae Constantin BalicaNicolae Constantin Balica
Nicolae Constantin Balica
SMSorin Bogdan Motoi
Sorin Bogdan Motoi
GIGheorghe Iovanescu
Gheorghe Iovanescu
MGMadalina Georgescu
Madalina Georgescu
GLGRIGORITA LAURA
GRIGORITA LAURA
Conclusions: HRCT is a valuable tool in preoperative assessment of cholesteatoma, helping in making surgical decisions. It can accurately predict the extent of disease and is helpful for detecting unapparent dangerous situations. However it is not very accurate in detecting Fallopian canal and stapes erosion.

10 March 2024 in Medicina
Verified
Journal Article
Open access
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DCDan Costachescu
Dan Costachescu
AMAlexandru Catalin Motofelea
Alexandru Catalin Motofelea
DMDaniel Malita
Daniel Malita
FBFlorica Birsasteanu
Florica Birsasteanu
IIIoana Ionita
Ioana Ionita
SMSorin Bogdan Motoi
Sorin Bogdan Motoi
Although ovarian cystic teratoma is the most common ovarian tumor, complications are quite rare. However, it is important to be recognized by the radiologist in order to avoid inaccurately diagnosing them as malignant lesions. This case report describes a 61-year-old postmenopausal woman, who presented to the emergency room with abdominal pain following a minor blunt abdominal trauma. In this context, a CT scan was performed, which showed the presence of round, hypodense masses randomly distributed in the peritoneum, with coexisting ascites in moderate amount; ovarian carcinoma with peritoneal carcinomatosis was suspected. The patient was hospitalized and an MRI of the abdomen and pelvis was recommended for a more detailed lesion characterization. Following this examination, the patient was diagnosed with mature cystic ovarian teratoma complicated by rupture. Surgery was performed, and the outcome was favorable. The cases of ruptured cystic teratomas are rare, and to our knowledge, this is the first occurrence described in literature. Special attention must be paid when confronting with such a case in medical practice, since it can easily misdiagnosed as peritoneal carcinomatosis.

3 April 2020 in Revista de Chimie
Verified
Journal Article
Open access
SMSorin Bogdan Motoi
Sorin Bogdan Motoi
ADAmadeus Dobrescu
Amadeus Dobrescu
SCSimona Carabineanu
Simona Carabineanu
ABAlexandru Iulian Ciprian Blidisel
Alexandru Iulian Ciprian Blidisel
Dana StoianDana Stoian
Dana Stoian
DNDan Navolan
Dan Navolan
REVISTA DE CHIMIE founded in 1949 edited by the REVISTA DE CHIMIE SRL, review in Chemical Abstracts, Current Contents,Analytical Abstracts, SCOPUS

26 February 2024 in Preprints.org
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DCDan Costachescu
Dan Costachescu
AMAlexandru Catalin Motofelea
Alexandru Catalin Motofelea
DMDaniel Malita
Daniel Malita
FBFlorica Birsasteanu
Florica Birsasteanu
IIIoana Ioniță
Ioana Ioniță
SMSorin Bogdan Motoi
Sorin Bogdan Motoi
Although ovarian cystic teratoma is the most common ovarian tumor, complications are quite rare. However, it is important to be recognized by the radiologist in order to avoid inaccurately diagnosing them as malignant lesions. This case report describes a 61-year-old postmenopausal woman, who presented to the emergency room with abdominal pain following a minor blunt abdominal trauma. In this context, a CT scan was performed, which showed the presence of round, hypodense masses randomly distributed in the peritoneum, with coexisting ascites in moderate amount; ovarian carcinoma with peritoneal carcinomatosis was suspected. The patient was hospitalized and an MRI of the abdomen and pelvis was recommended for a more detailed lesion characterization. Following this examination, the patient was diagnosed with mature cystic ovarian teratoma complicated by rupture. Surgery was performed, and the outcome was favorable. The cases of ruptured cystic teratomas are rare, and to our knowledge, this is the first occurrence described in literature. Special attention must be paid when confronting with such a case in medical practice, since it can easily misdiagnosed as peritoneal carcinomatosis