Salmonella osteomyelitis (OM) is more common in individuals with hemoglobinopathies like sickle cell anemia or thalassemia. The cardinal symptoms of OM such as fever, pain, and soft tissue swelling do not point towards a specific etiological agent. Since a preceding history of gastrointestinal infections is usually absent it causes a diagnostic challenge for Salmonella OM which is often overlooked causing a delay in diagnosis. In cases of fluoroquinolone resistance, third generation cephalosporins become the drug of choice. Due to absence of standardized guidelines, management is usually on a case-to-case basis. Previous studies have been focused mostly on children. Here, we present a rare case of Salmonella typhi OM in a 25-year male without any common predisposing factors.
15 June 2022 in IP International Journal of Medical Microbiology and Tropical Diseases
Is a notorious superbug that is rapidly becoming the most common nosocomial pathogen to be isolated from intensive care settings. : To determine the burden of and associated risk factors of late onset sepsis among neonates admitted into neonatal intensive care unit (NICU).: A prospective study was conducted among 200 neonates admitted into the NICU of Sassoon General Hospital from January 1, 2019 to December 31, 2019. Neonates 72hrs after birth were included in the study. A detailed case history format of patient information was prepared. Blood sample was subjected to identification by culture and real time polymerase chain reaction (RT-PCR). Neonates who were positive by blood culture were confirmed as having sepsis.: Frequency of was 33.3% by blood culture and 38.1% by RT-PCR. Most of the septic neonates were males (n=6; 60%), formula fed (n=7; 70%), extremely low birth weight (n=6; 60%), delivered through caesarean section (n=6, 60%) and were preterm (n=7; 70%). Mortality was seen in 2 (20%) cases. All the isolates were sensitive to meropenem, piperacillin + tazobactam, amikacin, polymyxin B and colistin. : Occurrence of was 33.3% in late onset neonatal sepsis by blood culture. Low birth weight, formula feeding, prematurity and caesarean section were associated with a higher risk of sepsis in these patients. Antimicrobial stewardship and hospital infection control measures are need of the hour in preventing late onset neonatal sepsis.
15 January 2023 in IP International Journal of Medical Paediatrics and Oncology
The re-emergence of hand, foot and mouth disease: Are we awaiting an epidemic? - IJMPO- Print ISSN No: - 2581-4699 Online ISSN No:- 2581-4702 Article DOI No:- 10.18231/j.ijmpo.2022.042, IP International Journal of Medical Paediatrics and Oncology-IP Int J Med Paediatr Oncol
15 July 2023 in Indian Journal of Microbiology Research
Cryptosporidiosis in HIV-seronegative patients: A case series - IJMR- Print ISSN No: - 2394-546X Online ISSN No:- 2394-5478 Article DOI No:- 10.18231/j.ijmr.2023.019, Indian Journal of Microbiology Research-Indian J Microbiol Res