Maria Condello

Dr. Maria Condello

National Center for Drug Research and Evaluation, National Institute of Health, Viale Regina Elena, 00161 Rome, Italy
orcid

Research Focus & Metrics

Academic Career Length

22Years (2005-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 August 2010 in Toxicology and Applied Pharmacology
Verified
Journal Article
Closed access
BBBarbara De Berardis
Barbara De Berardis
GCGabriele Civitelli
Gabriele Civitelli
Maria CondelloMaria Condello
Maria Condello
PLPasquale Lista
Pasquale Lista
RPRoberta Pozzi
Roberta Pozzi
Stefania MeschiniStefania Meschini
Stefania Meschini

13 July 2016 in Oncotarget
Verified
Journal Article
Open access
LLLuana Lugini
Luana Lugini
MVMauro Valtieri
Mauro Valtieri
CFCristina Federici
Cristina Federici
SCSerena Cecchetti
Serena Cecchetti
Stefania MeschiniStefania Meschini
Stefania Meschini
Stefano FaisStefano Fais
Stefano Fais
Exosomes from human colorectal cancer induce a tumor-like behavior in colonic mesenchymal stromal cells

Verified
Journal Article
Open access
PDF file
Maria CondelloMaria Condello
Maria Condello
EPEvelin Pellegrini
Evelin Pellegrini
Michele CaragliaMichele Caraglia
Michele Caraglia
Stefania MeschiniStefania Meschini
Stefania Meschini
Autophagy is an evolutionarily conserved cellular process, through which damaged organelles and superfluous proteins are degraded, for maintaining the correct cellular balance during stress insult. It involves formation of double-membrane vesicles, named autophagosomes, that capture cytosolic cargo and deliver it to lysosomes, where the breakdown products are recycled back to cytoplasm. On the basis of degraded cell components, some selective types of autophagy can be identified (mitophagy, ribophagy, reticulophagy, lysophagy, pexophagy, lipophagy, and glycophagy). Dysregulation of autophagy can induce various disease manifestations, such as inflammation, aging, metabolic diseases, neurodegenerative disorders and cancer. The understanding of the molecular mechanism that regulates the different phases of the autophagic process and the role in the development of diseases are only in an early stage. There are still questions that must be answered concerning the functions of the autophagy-related proteins. In this review, we describe the principal cellular and molecular autophagic functions, selective types of autophagy and the main in vitro methods to detect the role of autophagy in the cellular physiology. We also summarize the importance of the autophagic behavior in some diseases to provide a novel insight for target therapies.

1 September 2016 in Toxicology in Vitro
Verified
Journal Article
Closed access
Maria CondelloMaria Condello
Maria Condello
BBBarbara De Berardis
Barbara De Berardis
MAMaria Grazia Ammendolia
Maria Grazia Ammendolia
FBFlavia Barone
Flavia Barone
Giancarlo CondelloGiancarlo Condello
Giancarlo Condello
Stefania MeschiniStefania Meschini
Stefania Meschini

1 January 2012 in Biotechnology Advances
Verified
Journal Article
Closed access
Giovanni VitaleGiovanni Vitale
Giovanni Vitale
SZSilvia Zappavigna
Silvia Zappavigna
MMMonica Marra
Monica Marra
ADAlessandra Dicitore
Alessandra Dicitore
Stefania MeschiniStefania Meschini
Stefania Meschini
Michele CaragliaMichele Caraglia
Michele Caraglia

16 November 2008 in Autophagy
Verified
Journal Article
Closed access
Stefania MeschiniStefania Meschini
Stefania Meschini
Maria CondelloMaria Condello
Maria Condello
ACAnnarica Calcabrini
Annarica Calcabrini
MMManuela Marra
Manuela Marra
GFGiuseppe Formisano
Giuseppe Formisano
GAGiuseppe Arancia
Giuseppe Arancia
In our previous studies, the bisindolic alkaloid voacamine (VOA), isolated from the plant Peschiera fuchsiaefolia, proved to exert a chemosensitizing effect on cultured multidrug resistant (MDR) os...