In this work, the oxidation properties of low-iron vanadium-titanium magnetite with high vanadium and titanium in a laboratory muffle furnace was investigated. XRD, SEM, and TG-DSC method are employed to identify the main phases and chemical composition of the samples. The roasting time of 4h and Na₂CO₃/vanadium titanium magnetite mass ratio of 7.5:100 were determined. The results showed that the blank oxidation roasting temperature ranged from 593°C to 1035°C, the mixed oxidation roasting temperature of vanadium-titanium magnetite and Na₂CO₃ at the range of 204°C to 825°C, and the forming temperature of soluble vanadate at the range of 700°C to 825°C. When roasting temperature reached 1000°C, consolidation was started. When roasting temperature was 850°C, the roasting conversion efficiency, acid leaching efficiency and water leaching efficiency were 92.4%, 87%, and 85%, respectively.