Background: Neuropsychiatric cases require a multidisciplinary approach for effective management. This paper presented case-based discussions on migraine, dementia, epilepsy, mood disorders, neuralgia, and psychosis from the perspectives of a family physician, neurologist, and psychiatrist. The goal was to highlight the importance of collaboration between healthcare providers in managing these complex cases. Methods: The paper was based on the proceedings of the Mediterranean Neuropsychiatry Symposium, where experts from family medicine, neurology, and psychiatry came together for comprehensive case-based discussions. The CARE framework (Case Report, Appraisal, Research, and Education) was developed to guide reporting and evaluation of case reports in clinical practice. Results: Six cases were presented and discussed, highlighting the importance of a multidisciplinary approach in managing neuropsychiatric cases. The cases included chronic migraine with medication overuse, memory dysfunction with language and behavioral problems, refractory epileptic seizures with subjective sensory symptoms, bipolar affective disorder with normal pressure hydrocephalus, postherpetic neuralgia in a case with bipolar affective disorder, and psychosis with recurrent attacks with the abuse of several substances. Conclusion: A biopsychosocial multidisciplinary approach is essential for managing neuropsychiatric cases effectively on behalf of the patients and public health of the country. The CARE framework can guide the reporting and evaluation of case reports in clinical practice, ensuring that patients receive comprehensive and effective care. Healthcare providers should collaborate to provide the best possible care for patients with complex and multifaceted needs.

Pandemi gibi tüm dünyayı etkileyen ölümlere neden olan salgınlarda, toplumun psikososyal, ekonomik ve fiziksel kayıplardan etkilenmesinin yanı sıra; topluma en önde ruhsal ve fiziksel hizmet sunan sağlık çalışanları en çok etkilenen grup olmaktadır. Küresel tehdit oluşturan bu tür salgınlar; toplumda endişe, depresyon, ölüm kaygısı, yakınlarını kaybetme endişesi, belirsizliğe tahammülsüzlik gibi psikiyatrik belirtilere, salgın nedeniyle karantina uygulamalarının oluşturduğu psikososoyal ve ekonomik güçlüklere neden olmaktadır. Toplumun yanı sıra, tüm toplumu sosyoekonomik ve ruhsal yönden etkileyen pandemilerde; büyük ölçüde sosyal ve iş sorumluluğu yüklenen sağlık çalışanlarının ruhsal sağlığı da etkilenmektedir. Bu nedenle yazımızda; 2020 yılında tüm dünyayı etkisi altına alan COVID-19 pandemisinin, toplum ve sağlık çalışanları üzerindeki ruhsal etkisini ve alınabilecek koruyucu önlemleri derlemeyi planladık.

In schizophrenia, the relationship between suicide and cognition is unclear. We aimed to assess cognitive functions and insight in schizophrenia patients with and without suicide attempts. In our study consisting of 77 patients, 36 of the patients had attempted suicide at least once in their lives and the remaining 41 had never attempted suicide. Sociodemographic data scale, Beck Cognitive Insight Scale, and Cambridge Neurophysiological Assessment Battery were applied. In this study, patients with schizophrenia who attempted suicide had higher Beck Cognitive Insight Scale self-reflectiveness scores (P = .004), lower Beck Cognitive Insight Scale self-certainty scores (P = .040), and higher Beck Cognitive Insight Scale total score (P = .004). Delay aversion (P = .003) and risk-taking scores (P = .044) of Cambridge Neurophysiological Assessment Battery Cambridge gambling task were higher in patients who attempted suicide. In logistic regression analysis, as independent factors, the number of hospitalizations increased the risk of suicide 1.5 times per hospitalization (P = .021), Cambridge gambling task delay aversion increased the risk of suicide 8.4 times per score (P = .044), and the Beck Cognitive Insight Scale self-certainty score was shown as the factor that decreased the risk of suicide by 0.78 times (P = .024). The causes of suicide attempts in schizophrenia still preserve its uncertainty. Our results proposed a statistically significant relationship between cognitive insight and increased suicide attempts. This study also sustains that cognitive impulsivity is associated with suicidal behavior in patients with schizophrenia.

Objective Emotion regulation is an important skill to cultivate in patients with obsessive-compulsive disorder (OCD) for helping with the positive prognosis of their disease. Patients with OCD exhibit higher rates of impulsivity compared to healthy volunteers. According to previous studies, there is significant impairment in the quality of life in OCD. Despite their importance, no study has yet been conducted on the interrelation of these clinical parameters in OCD patients. We investigated the relationship between disease severity, emotional dysregulation, impulsivity, and quality of life in untreated OCD patients.Methods This study included 40 untreated outpatients with a diagnosis of OCD. We applied the following form and scales: Sociodemographic and clinical data form, the Yale-Brown Obsessive Compulsive Scale, the Difficulties in Emotion Regulation Scale, the Barratt Impulsiveness Scale Short Form, and the World Health Organization Quality of Life Scale Short Form.Results We found a positive relationship (p<0.001) between emotional dysregulation and impulsivity in OCD patients. A positive relationship (p=0.003) was identified between disease severity and emotional dysregulation, while an inverse relationship (p<0.001) was observed between disease severity and quality of life-psychological health. Increased impulsivity and emotional dysregulation were also associated with a deterioration in quality of life.Conclusion There is a significant positive relationship between emotional dysregulation and impulsivity in OCD patients. These clinical parameters may serve as important targets for treatment approaches in OCD patients and thus should be considered in the future work.

Objective: One of the most important predictors of the severity of major depressive disorder is the presence of a comorbid anxiety disorder. Independent of treatment, depressed patients with a lifetime anxiety disorder are found to have a slower response to treatment and lower symptomatic recovery rates compared to depressed patients without a lifetime anxiety disorder. In this study, the aim was to compare the Lifetime Panic-Agoraphobic Spectrum and sociodemographic characteristics of patients with major depressive disorder and healthy controls and to investigate its relationship with depressive disorder severity and anxiety levels. Methods: A total of 135 participants were included in the study, 80 of whom were major depressive disorder patients. Beck Anxiety Scale, Beck Depression Scale, Lifetime Panic Agoraphobic Spectrum Scale, and a sociodemographic and clinical data form were applied to all participants. Results: All Lifetime Panic Agoraphobic Spectrum subscale scores, Lifetime Panic Agoraphobic Spectrum total score, Beck Depression Inventory, and Beck Anxiety Inventory scores are found to be significantly higher in the major depressive group compared to healthy controls. Also, Lifetime Panic Agoraphobic Spectrum scores and Beck Depression Inventory scores are found to be significantly higher in patients with melancholic depression compared to patients with atypical depression. Conclusion: The findings demonstrate that panic-agoraphobic spectrum characteristics are significantly associated with depression severity, especially in melancholic depression. Even in the absence of a comorbid anxiety disorder, the assessment of Panic-Agoraphobic Spectrum features and identification of the depression subtype can provide valuable insights for personalized treatment approaches and may lead to improved clinical outcomes.Cite this article as: Gürbüz MS, Erzincan E, İzci F, Beştepe EE. Evaluation of panic agoraphobic spectrum and sociodemographic characteristics in terms of depression types. Neuropsychiatr Invest. 2025, 63, 0051, doi:10.5152/ NeuropsychiatricInvest.2025.24051.