Si-An Lee

Ms. Si-An Lee

orcid

Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2024 in Digital Health
Verified
Journal Article
Open access
SLSi-An Lee
Si-An Lee
SHSeoyoon Heo
Seoyoon Heo
Jin-Hyuck ParkJin-Hyuck Park
Jin-Hyuck Park
Background: ChatGPT is an artificial intelligence-based large language model (LLM). ChatGPT has been widely applied in medicine, but its application in occupational therapy has been lacking. Objective: This study examined the accuracy of ChatGPT on the National Korean Occupational Therapy Licensing Examination (NKOTLE) and investigated its potential for application in the field of occupational therapy. Methods: ChatGPT 3.5 was used during the five years of the NKOTLE with Korean prompts. Multiple choice questions were entered manually by three dependent encoders, and scored according to the number of correct answers. Results: During the most recent five years, ChatGPT did not achieve a passing score of 60% accuracy and exhibited interrater agreement of 0.6 or higher. Conclusion: ChatGPT could not pass the NKOTLE but demonstrated a high level of agreement between raters. Even though the potential of ChatGPT to pass the NKOTLE is currently inadequate, it performed very close to the passing level even with only Korean prompts.

4 June 2025 in Healthcare
Verified
Journal Article
Open access
PDF file
SLSi-An Lee
Si-An Lee
Jin-Hyuck ParkJin-Hyuck Park
Jin-Hyuck Park
Background/Objectives: Case-based learning is essential in occupational therapy education, but developing standardized cases requires significant resources. This study explores the usability of AI-generated case studies using ChatGPT. Methods: A four-stage process was applied: (1) prompt development based on existing frameworks, (2) case generation ensuring diversity and relevance, (3) expert evaluation using a 5-point Likert scale, and (4) data analysis. Five neurological cases were generated and reviewed by ten experts. Results: Experts rated the cases highly in clinical realism (4.22/5), information comprehensiveness (4.56/5), and educational value (4.44/5). The AI-generated cases successfully provided structured occupational therapy scenarios, assessment results, and clinical questions. Conclusions: Five AI-generated occupational therapy cases were developed and reviewed by occupational therapy experts to evaluate their clinical realism, comprehensiveness, and educational value. While expert feedback was favorable, the effectiveness of these cases for student learning has not yet been empirically tested.

1 May 2025 in Digital Health
Verified
Journal Article
Open access
SLSi-An Lee
Si-An Lee
Jin-Hyuck ParkJin-Hyuck Park
Jin-Hyuck Park
Background: Artificial intelligence (AI)-based language models such as ChatGPT show promise in generating medical documentation. However, their effectiveness in occupational therapy (OT) documentation—particularly in terms of perceived quality and empathy—remains underexplored. Objective: This study aimed to compare the quality and empathy of clinical documentation generated by licensed occupational therapists versus ChatGPT-3.5, using standardized OT case scenarios. Methods: Fifteen standardized OT cases were used to generate human- and AI-written assessment and plan sections. Five occupational therapists and five patients or caregivers independently evaluated the documentation using 5-point Likert scales across three quality subdomains (completeness, correctness, concordance) and three empathy dimensions (cognitive, affective, behavioral). Inter-rater reliability and correlations between quality and empathy were also analyzed. Results: Artificial intelligence-generated documentation received significantly higher ratings across all quality and empathy dimensions than human-generated documentation (all p < 0.001). However, human-generated documentation demonstrated stronger correlations between quality and empathy, and higher inter-rater reliability, indicating greater consistency among evaluators. These findings suggest that while AI can produce responses perceived as more complete and empathetic, its outputs may vary more widely in interpretation. Conclusion: Artificial intelligence-based tools may help reduce documentation burdens for therapists by generating high-quality, empathetic notes. However, human-authored documentation remains more consistent across evaluators. These results underscore the potential and limitations of AI in clinical documentation, highlighting the need for further development to enhance contextual sensitivity, communication coherence, and evaluator reliability. Future research should examine AI performance in real-world OT practice settings.

9 November 2023 in Brain Sciences
Verified
Journal Article
Open access
PDF file
SLSi-An Lee
Si-An Lee
JKJi-Yea Kim
Ji-Yea Kim
Jin-Hyuck ParkJin-Hyuck Park
Jin-Hyuck Park
To date, budget management in virtual shopping training has not been given much importance. The main objective of this study was to investigate the effects of virtual shopping budget-management training on executive functions and brain activation. Sixteen participants were randomly assigned to the experimental group that received virtual shopping budget-management training or the waitlist control group for a total of 16 sessions. To examine the effects of virtual shopping budget-management training on brain activation, HbO2 was measured in the prefrontal cortex via functional near-infrared spectroscopy (fNIRS) during the Trail Making Test Part B (TMT-B) and Stroop test. Mann–Whitney and Wilcoxon signed-rank tests were used to compare outcomes between and within the two groups. The virtual shopping budget-management training showed no significant difference in all outcomes between both groups (p > 0.05). No significant differences were observed in HbO2 levels during both TMT-B (p > 0.05) and the Stroop test (p > 0.05). However, in the pre-post comparisons, there was a significant difference in the TMT-B (p < 0.05) and Stroop test (p < 0.05) in the experimental group. In this study, although we did not find a distinct advantage in training, it confirmed its potential for clinical benefits in healthy young adults through training.

12 January 2024 in Brain Sciences
Verified
Journal Article
Open access
PDF file
SLSi-An Lee
Si-An Lee
JHJun-Hwa Hong
Jun-Hwa Hong
NKNa-Yeon Kim
Na-Yeon Kim
HMHye-Min Min
Hye-Min Min
HYHa-Min Yang
Ha-Min Yang
Jin-Hyuck ParkJin-Hyuck Park
Jin-Hyuck Park
The widespread use of mobile devices and laptops has replaced traditional paper-based learning and the question of how the brain efficiency of digital tablet-based learning differs from that of paper-based learning remains unclear. The purpose of this study was to investigate the difference in brain efficiency for learning between paper-based and digital tablet-based learning by measuring activity in the prefrontal cortex (PFC) using functional near-infrared spectroscopy. Thirty-two subjects were randomly assigned to the paper-based learning or the digital tablet-based learning group. Subjects in each group performed a memory task that required memorizing a three-minute novel (encoding phase) on a paper or digital tablet, followed by a test in which they answered four multiple-choice questions based on the novel’s content. To compare both groups, behavioral performance on the test (retrieval phase) and activity in the PFC were measured. As a result, no significant difference in behavioral performance between both groups was observed (p > 0.05). However, the paper-based learning group showed significantly lower activity in the PFC in the encoding phase than the digital tablet-based learning group (p < 0.05) but not in the retrieval phase. The current study demonstrated that brain efficiency in encoding is higher in subjects with paper-based learning than those with digital tablet-based learning. This finding has important implications for education, particularly in terms of the pros and cons of electronic document-based learning.

4 May 2026 in Journal of Medical Internet Research
Verified
Journal Article
Open access
SLSi-An Lee
Si-An Lee
Jin-Hyuck ParkJin-Hyuck Park
Jin-Hyuck Park
Background: Obesity is a major global health concern, and scalable digital solutions are urgently needed. While digital lifestyle interventions (DLSIs) have shown promise, prior meta-analyses often included hybrid formats with human support, limiting insights into the effectiveness of fully digital interventions. Objective: This study aimed to evaluate the independent effects of standalone DLSIs—defined as interventions delivered exclusively via digital platforms without in-person or adjunctive support—on anthropometric and dietary outcomes in adults with overweight or obesity. Methods: We searched MEDLINE, Embase, PsycINFO, Web of Science, and the Cochrane Library from inception through March 4, 2026. Eligible studies were randomized controlled trials (RCTs) evaluating stand-alone DLSIs in adults with overweight or obesity. Interventions were included if they targeted diet or physical activity exclusively through digital platforms. We included fully automated, asynchronous, or one-to-many synchronous systems without individualized support. Studies involving hybrid interventions, including one-to-one synchronous human interaction, nonadult populations, or non-RCT designs, were excluded. Two independent reviewers performed study selection and data extraction. Risk of bias was assessed using the Cochrane Risk of Bias 2.0 tool (Cochrane Bias Methods Group). Meta-analysis used a random-effects model with the Hartung-Knapp-Sidik-Jonkman method, and heterogeneity was assessed using I 2 statistics. The certainty of evidence was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluation approach. Results: A total of 19 RCTs involving 3556 participants were included. Stand-alone DLSIs significantly improved anthropometric outcomes compared to controls (standardized mean difference 0.26, 95% CI 0.14‐0.38; 95% prediction interval [PI] −0.16 to 0.68; P <.001; 19 studies; n=3556; I 2 =56.1%), corresponding to an additional weight loss ranging from 2.62 kg to 6.55 kg, depending on the baseline body weight. Significant improvements were also found in dietary outcomes (standardized mean difference 0.26, 95% CI 0.04‐0.48; 95% PI −0.29 to 0.81; P =.008; 8 studies; n=1365; I 2 =57.5%). Subgroup analyses for anthropometric outcomes revealed significant differences only by control group type ( P <.001), with waitlist controls showing the largest effect. For dietary outcomes, no significant subgroup differences were found ( P >.05). While most studies showed a low risk of bias, substantial statistical heterogeneity was observed in some outcomes. Consequently, the certainty of evidence for both outcomes was rated as moderate. Conclusions: This review is innovative as it is the first to isolate the pure efficacy of stand-alone DLSIs by excluding synchronous human support. Our findings provide moderate-certainty evidence that these tools are effective for weight management and dietary improvement without human intervention. While stand-alone DLSIs offer a highly scalable, cost-effective first-step intervention, the PIs included zero, and substantial heterogeneity was observed, suggesting that benefits may vary across settings. Future research should identify user characteristics that maximize engagement with unguided digital tools.