Introduction: The population is susceptible to COVID-19 and knowing the most predominant characteristics and comorbidities of those affected is essential to diminish its effects. Objective: This study analyzed the biological, social and clinical risk factors for mortality in hospitalized patients with COVID-19 in the district of Trujillo, Peru. Methods: A descriptive type of study was made, with a quantitative approach and a correlational, retrospective, cross-sectional design. Data was obtained from the Ministry of Health’s database, with a sample of 64 patients from March to May 2020. Results: 85,71% of the total deceased are male, the most predominant occupation is Retired with an 28,57% incidence, and an average age of 64,67 years. When it came to symptoms of deceased patients, respiratory distress represents the highest percentage of incidence with 90,48%, then fever with 80,95%, followed by malaise in general with 57,14% and cough with 52,38%. The signs that indicated the highest percentage in deaths were dyspnea and abnormal pulmonary auscultation with 47,62%, in Comorbidities patients with cardiovascular disease were found in 42,86% and 14,29% with diabetes. The logistic regression model to predict mortality in hospitalized patients allowed the selection of risk factors such as age, sex, cough, shortness of breath and diabetes. Conclusion: The model is adequate to establish these factors, since they show that a fairly considerable percentage of explained variation would correctly classify 90,6% of the cases. Introducción: La población es susceptible al COVID-19 y conocer las características y comorbilidades más predominantes de los afectados resulta imprescindible para disminuir sus efectos. Objetivo: El presente estudio analizó los factores biológicos, sociales y clínicos de riesgo de mortalidad en pacientes hospitalizados con COVID-19 en el distrito de Trujillo, Perú. Métodos: El tipo de estudio fue descriptivo, de enfoque cuantitativo y diseño correlacional, retrospectivo, de corte transversal. Se obtuvieron los datos del sistema del Ministerio de Salud, con una muestra de 64 pacientes de marzo a mayo del 2020. Resultados:El 85,71% del total de fallecidos son del sexo masculino, la ocupación más predominante es jubilados con un 28,57% y tienen una edad promedio de 64,67 años. En el caso de los síntomas en pacientes fallecidos la dificultad respiratoria representa el mayor porcentaje 90,48%; la fiebre con un 80,95%, seguido de un malestar en general con un 57,14% y tos con un 52,38%. Los signos con mayor porcentaje en fallecidos fueron la disnea y auscultación pulmonar encontraron anormal con un 47,62%, en Comorbilidades se pacientes con enfermedad cardiovascular en un 42,86% y un 14,29% con diabetes. El modelo de regresión logística para predecir la mortalidad en pacientes hospitalizados incluidos la selección de factores de riesgo como edad, sexo, tos, dificultad respiratoria y diabetes. Conclusión: El modelo es el adecuado para establecer estos factores, ya que mostró que un porcentaje de variación explicada bastante considerable, clasificaría correctamente el 90,6% de los casos.

Purpose: The presence of the COVID-19 coronavirus in Peru, and especially in northern Peru, was very fast and caused many deaths. As a result, vaccination proved to be the most immediate option to control it. However, a sector of the population was reluctant to vaccination. Therefore, this study aimed to analyze the factors associated with the acceptance of COVID-19 vaccines by citizens of northern Peru. Patients and Methods: The study was observational, descriptive-correlational and the sample was stratified and consisted of 516 citizens from eight departments of northern Peru, who answered an online questionnaire regarding sociodemographic, cultural and health aspects. The data were analyzed using statistical tests of association and a logistic model was estimated to identify factors predicting vaccine acceptance. Results: Among the factors associated with vaccine acceptance, sociodemographic factors such as age and family income, cultural factors such as level of knowledge, and health factors such as having another chronic disease and a vaccine with a higher confidence (p<0.05) were found. In addition, 12% of the population do not trust them, 10% are afraid that they may cause thrombosis, 13% disagree with vaccination for children, 7% think that a chip will be implanted and 8% believe that their DNA will be changed. However, most people accept vaccination and consider it necessary. A multivariate analysis was also performed for the acceptance of vaccines, which presented a percentage of 80.2% correct in the prognosis. Conclusion: The multivariate analysis allowed a conclusion that the predictor variables for vaccine acceptance are household income of less than 1000 Peruvian soles per month, low or medium levels of knowledge, and having another chronic disease.

Objective: To analyze the questionnaire of the validity and reliability of knowledge, attitudes and practices concerning Mpox. Methods: This was an instrumental, cross-sectional study. The sample consisted of 178 citizens from 3 sectors of Peru, who responded to a virtual questionnaire regarding knowledge, attitudes and practices concerning Mpox. The validity and reliability process of the questionnaire was carried out using Aiken’s V, Cronbach’s Alpha, McDonald’s Omega and principal component analysis. Results: After expert evaluation, the questionnaire was shown to have adequate content validity for measuring knowledge, attitudes and practices concerning Mpox, each in their respective dimensions, with Aiken’s V values above 0.90. For construct validity, exploratory factor analysis was used and the items were grouped into four dimensions for the level of knowledge, three dimensions for attitudes, and two for practices. With respect to the reliability analysis, the application of Cronbach’s α statistic and McDonald’s ω, obtained values above 0.70. Conclusion: The results of the research enabled the attainment of a questionnaire that meets the adequate psychometric characteristics in order to be applied.

Introduction: Excessive workload in health personnel, due to the COVID-19 pandemic, has generated the presence of Burnout Syndrome. The purpose of this study was to determine a logistic model for the factors associated with the dimensions of Burnout Syndrome in health personnel during the COVID-19 pandemic in Trujillo - Peru.Method: A cross-sectional, correlational design was applied. The standardized Maslach Burnout Inventory questionnaire was used and applied virtually. It measures emotional exhaustion, depersonalization and personal fulfillment. The sample consisted of 143 health professionals from the Trujillo Micro-network and Social Health Insurance establishments (ESSALUD).Results: 24.5% of health professionals have a high level of emotional exhaustion, 27.3% a high level of depersonalization and 39.9% a low level of personal fulfillment. Marital status, family income, type of institution where they work, age and number of children are associated with the level of emotional exhaustion (p<0.05). Gender, profession, type of institution, age and number of children are associated with the level of depersonalization (p<0.05). The type of institution and age are associated with the level of personal fulfillment (p<0.05). Conclusions: The proposed ordinal logistic model indicates 69.2% success in emotional exhaustion level, 60.8% success for depersonalization level and 58.7% with the model for personal fulfillment level. Introducción: La carga de trabajo excesiva en el personal de salud, debido a la pandemia del COVID-19 ha generado la presencia del Síndrome de Burnout. El propósito de este estudio fue determinar un modelo logístico para los factores asociados a las dimensiones del Síndrome de Burnout en el personal de salud, durante la pandemia COVID-19, en Trujillo - Perú.Método: Se aplicó un diseño transversal, correlacional; se utilizó el cuestionario estandarizado del inventario de Burnout de Maslach aplicado virtualmente, que mide: agotamiento emocional, despersonalización y realización personal, la muestra estuvo conformada por 143 profesionales de salud de los establecimientos de la Micro red de Trujillo y de El Seguro Social de Salud (ESSALUD), Resultados: El 24,5% de profesionales de la salud tienen un nivel de agotamiento emocional alto, 27,3% nivel de despersonalización alto y 39,9% nivel de realización personal bajo. El estado civil, ingreso familiar, tipo de institución donde labora, la edad y el número de hijos se asocian al nivel de agotamiento emocional (p<0,05). El sexo, la profesión, tipo de institución, edad y número de hijos se asocian al nivel de despersonalización (p<0,05). El tipo de institución y la edad se asocian al nivel de realización personal (p<0,05). Conclusiones: El modelo logístico ordinal propuesto indica el 69,2% de éxito en nivel de agotamiento emocional, el 60,8% de éxito para el nivel de despersonalización y el 58,7% con el modelo para nivel de realización personal.

Objective: To analyze the factors associated with leishmaniasis in Peru, according to the cluster classification in the period 2017–2021. Methods: Quantitative approach, with an ecological, descriptive correlational, and cross-sectional design. The population was from the geographical region of Peru, where a total of 26,956 cases of leishmaniasis were registered by the Peruvian Ministry of Health from 2017 to 2021. Spearman’s Rho statistic was used to analyze the variables that are most associated with the cases of leishmaniasis reported per year, and, in addition, the multivariate technique of cluster analysis was applied. Results: Annual rainfall and areas with humid forest (climatic factors) and mortality from transmissible diseases (health factor) are directly associated with reported cases of leishmaniasis. Households with basic access to infrastructure, drinking water, drainage, and electric lighting; illiteracy, regional social progress, and unsatisfied basic needs (social factors); and percentage of urban population (demographic factor) are inversely and significantly associated with cases of leishmaniasis. Conclusions: Climatic and environmental factors contribute to the multiplication of the leishmaniasis disease vector. The incidence of leishmaniasis adds up to the mortality rates for transmissible diseases in Peru. As living conditions improve, the incidence of this pathology decreases.

Objetivo. Analizar los conocimientos, actitudes y prácticas preventivas frente a la segunda ola del COVID-19 en residentes de La Libertad- Perú. Material y métodos. Se aplicó un diseño transversal, correlacional; se utilizó un cuestionario debidamente validado y los datos fueron recolectados usando un formulario virtual a 294 residentes del departamento de La Libertad, cuya muestra fue hallada cumpliendo los parámetros estadísticos requeridos. Resultados. Las características de los encuestados fueron edad promedio de 28.3±9.9 años y 71.8% mujeres. Las personas con nivel de conocimiento bueno y actitud adecuada tenían características como estado civil casado o conviviente, tenían hijos, grado de instrucción superior y contaban con trabajo estable. Las variables edad y sexo son las que se asociaron al nivel de conocimiento y actitud, así como el hecho de conocer las formas de contagio, que se asoció significativamente con las actitudes y practicas preventivas que se tiene frente a la segunda ola del COVID-19, por último, un 38.1% de personas encuestadas indicaron que no confían en la efectividad de la vacuna. Conclusiones. Los residentes encuestados del departamento de la Libertad- Perú presentan buenos niveles de conocimiento, actitudes y practicas preventivas, sin embargo, se apreció que no tienen muy claro las formas de contagio y esto sumado a una mala economía, ha llevado al incremento de casos.