Purpose: The EphA2 receptor tyrosine kinase is believed to play a role in tumor growth and metastasis. The clinical significance of the expression of EphA2 was observed in breast, prostate, colon, skin, cervical, ovarian, and lung cancers. The purpose of this work was to determine the expression of EphA2 and its ligand, Ephrin A-1, and E-cadherin in carcinoma of the urinary bladder, and determine EphA2 as a new target for therapy in bladder cancer.

This study addresses the urgent need for comprehensive climate education amid a climate emergency. Human (energy) behaviors are developed from childhood and early adulthood. This study hypothesizes that transcending a nation’s net-zero energy ambition can be accomplished through experiential education. An Urban Governance Lab plus nEt-Zero Energy league model is introduced. Various behavioral interventions are designed based on the principles of serious games. Discussions provide rich narratives on how a nation with so many diverse communities can forge a rapid net-zero transition. The blended multi-disciplinary STEM education can drive energy citizenship in campus-like communities. A scenarios-based analysis demonstrating the potential of the proposed model in shaping energy behavior in young citizens leading to net zero is presented. The results from the scenario analysis present optimistic evidence underlining how campus-like communities driven by bottom-up initiatives can realize net-zero ambition beyond hope.