Roy O Mathew

Dr. Roy O Mathew

orcid

Research Focus & Metrics

Academic Career Length

16Years (2011-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 April 2017 in Kidney International
Verified
Journal Article
Closed access
RMRoy O Mathew
Roy O Mathew
SBSripal Bangalore
Sripal Bangalore
MLMichael P. Lavelle
Michael P. Lavelle
PPPatricia A. Pellikka
Patricia A. Pellikka
MSMandeep S. Sidhu
Mandeep S. Sidhu
AAArif Asif
Arif Asif

8 November 2023 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
SSSowmya Swamy
Sowmya Swamy
SNSahibzadi Mahrukh Noor
Sahibzadi Mahrukh Noor
RMRoy O Mathew
Roy O Mathew
Chronic kidney disease (CKD) is a common occurrence in patients with diabetes mellitus (DM), occurring in approximately 40% of cases. DM is also an important risk factor for cardiovascular disease (CVD), but CKD is an important mediator of this risk. Multiple CVD outcomes trials have revealed a greater risk for CVD events in patients with diabetes with CKD versus those without. Thus, reducing the risk of CKD in diabetes should result in improved CVD outcomes. To date, of blood pressure (BP) control, glycemic control, and inhibition of the renin-angiotensin system (RASI), glycemic control appears to have the best evidence for preventing CKD development. In established CKD, especially with albuminuria, RASI slows the progression of CKD. More recently, sodium glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide receptor agonists (GLP1RA) have revolutionized the care of patients with diabetes with and without CKD. SGLT2i and GLP1RA have proven to reduce mortality, heart failure (HF) hospitalizations, and worsening CKD in patients with diabetes with and without existing CKD. The future of limiting CVD in diabetes and CKD is promising, and more evidence is forthcoming regarding combinations of evidence-based therapies to further minimize CVD events.

1 April 2016 in Journal of the American Society of Hypertension
Verified
Journal Article
Closed access
RMRoy O Mathew
Roy O Mathew
ANAli Nayer
Ali Nayer
AAArif Asif
Arif Asif

20 January 2016 in Current Diabetes Reports
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Journal Article
Closed access
PDF file
CMCarlos E. Mendez
Carlos E. Mendez
PMPaul J. Der Mesropian
Paul J. Der Mesropian
RMRoy O Mathew
Roy O Mathew
BSBarbara Slawski
Barbara Slawski

22 August 2016 in Nephrology
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Journal Article
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PMPaul Der Mesropian
Paul Der Mesropian
JOJennifer Othersen
Jennifer Othersen
DMDarius Mason
Darius Mason
JWJeffrey Wang
Jeffrey Wang
AAArif Asif
Arif Asif
RMRoy O Mathew
Roy O Mathew

7 August 2018 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
MHMohammmad Hossain
Mohammmad Hossain
AAAmi Amin
Ami Amin
APAnju Paul
Anju Paul
HQHuzaif Qaisar
Huzaif Qaisar
MAMonika Akula
Monika Akula
AAArif Asif
Arif Asif
Background: While obesity is a chronic condition that predisposes patients to other more serious disorders, the prevalence and the documentation of obesity as diagnosis has not been extensively studied in hospitalized patients. We conducted a retrospective chart review to investigate the prevalence and documentation of obesity as a diagnosis among patients admitted to our medical center. Method: IRB approval was obtained for this retrospective study. Body mass index (BMI) as per CDC, admission and discharge diagnosis of obesity and common comorbidities (hypertension, diabetes, hyperlipidemia, coronary artery disease, congestive heart disease, chronic kidney disease and chronic obstructive pulmonary disease) were recorded. The length of stay in the hospital was also calculated. We also investigated whether counselling was provided to the obese patients for weight loss. Results: A total of 540 consecutive patients were reviewed with a mean age was 66 ± 6 years. Out of 540 patients only 182 (34%) had normal weight, 188 (35%) of the patients were overweight and 170 (31%) patients were obese. Of the obese group, 55% were female and 45% were male.100 (59%) had class I obesity, 43 (25%) had class II obesity and 27 (16%) class III obesity. Of the obese patients 40/170 (23.5%) patients had obesity documented on the admission problem list and only 21 (12%) had obesity documented as a discharge diagnosis. Only 3 (2%) patients were given appropriate counseling and referral for obesity management during the hospitalization. Comorbidities and their prevalence included, hypertension (68%), diabetes mellitus (35%), hyperlipidemia (36%), coronary artery disease (18%), chronic kidney disease (17%), congestive heart failure (18%) and COPD (24%). The average length of stay in normal weight, overweight and obese patients was similar for all three groups (4.5 ± 0.5 days). Conclusion: A significant number of hospitalized patients were overweight and obese. An overwhelming percentage never had weight status documented. Hospitalization offers health care providers a window of opportunity to identify obesity, communicate risks, and initiate weight management interventions.