Phytochemical investigation of the alkaloid composition in Pandanus amaryllifolius Roxb. and Pandanus tectorius Parkinson was carried out. Nine pandane alkaloids were isolated and determined. The alkaloids pandamarilactonine B, N-acetylnorpandamarilactonine A and pandamarilactonine G were found for the first time in P. tectorius. The total alkaloid mixtures and alkaloid fractions of the species were evaluated for their anti-inflammatory activity using in vitro experimental models.

Genus Hypecoum Tourn. ex L. belongs to the poppy family Papaveraceae and comprises about 19 species occurring in Europe, Northern Africa and Asia. Hypecoum species have been widely used in traditional medicine as antipyretic, analgesic and anti-inflammatory remedies. Their effects are associated with the biologically and pharmacologically active isoquinoline alkaloids in them, such as protopines, protoberberines, benzophenanthridines, aporphines, simple isoquinolines, secoberbines, spirobenzylisoquinolines and others. In this study, we aimed to review and organize information on ethnomedicinal, phytochemical, chemotaxonomical and pharmacological studies of alkaloids and extracts obtained from Hypecoum plants, and to suggest opportunities for further research.

A phytochemical study of Phellodendron amurense bark of Vietnamese origin was carried out to achieve a detailed characterisation of its alkaloid composition. A total of twelve alkaloids were isolated and determined, including four tertiary (canthin-6-one, γ-fagarine, skimmianine, and platydesmine), and eight quaternary alkaloids (berberine, palmatine, jatrorrhizine, columbamine, N-methyltetrahydrocolumbamine, N-methylcanadine, N-methylisocorydin (menisperine), and magnoflorine). Centrifugal partition chromatography operating in pH-zone-refining mode was successfully applied for the separation of quaternary isoquinoline alkaloids. The alkaloid N-methyltetrahydrocolumbamine is reported for the first time in the species P. amurense, while N-methylcanadine is newly found for the genus Phellodendron. The results demonstrate that P. amurense with Vietnamese origin retains the characteristic to the species alkaloid profile, dominated by protoberberine-type derivatives.