Dr. Carlos Olano graduated from the University of Oviedo in Biological Sciences in 1991 and obtained his doctorate in Biology in 1995. After a postdoctoral stay at the School of Pharmacy of the University of Wisconsin-Madison from 1997 to 2000, he returned to the University of Oviedo and served as a researcher at the University Institute of Oncology of the Principality of Asturias (IUOPA). In 2021, he became a Professor of Microbiology at the University of Oviedo. Since its inception, he has been part of the research group “Biosynthesis of bioactive compounds by microorganisms (BIOMIC)” at the University of Oviedo. Its medium-to-long-term scientific objectives focus on identifying new routes of secondary metabolites, produced by actinomycetes, through genomic mining; identifying new bioactive compounds produced by actinomycetes; the isolation and characterization of new biosynthesis routes of bioactive compounds; the application of combinatorial biosynthesis to generate new derivatives; and the use of genetic engineering strategies to activate cryptic/silent biosynthesis clusters identified by genomic mining in actinomycete genomes.
Research Keywords & Expertise
Biosynthesis
Nonribosomal Peptides
Bioactive natural prod...
anticancer agents
Antimicrobial agents
Polyketides
glycosylated compounds
Fingerprints
73%
Biosynthesis
33%
Polyketides
12%
Nonribosomal Peptides
8%
Bioactive natural products
8%
glycosylated compounds
5%
anticancer agents
Short Biography
Dr. Carlos Olano graduated from the University of Oviedo in Biological Sciences in 1991 and obtained his doctorate in Biology in 1995. After a postdoctoral stay at the School of Pharmacy of the University of Wisconsin-Madison from 1997 to 2000, he returned to the University of Oviedo and served as a researcher at the University Institute of Oncology of the Principality of Asturias (IUOPA). In 2021, he became a Professor of Microbiology at the University of Oviedo. Since its inception, he has been part of the research group “Biosynthesis of bioactive compounds by microorganisms (BIOMIC)” at the University of Oviedo. Its medium-to-long-term scientific objectives focus on identifying new routes of secondary metabolites, produced by actinomycetes, through genomic mining; identifying new bioactive compounds produced by actinomycetes; the isolation and characterization of new biosynthesis routes of bioactive compounds; the application of combinatorial biosynthesis to generate new derivatives; and the use of genetic engineering strategies to activate cryptic/silent biosynthesis clusters identified by genomic mining in actinomycete genomes.