Nicola Giannotta

Dr. Nicola Giannotta

orcid

Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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Journal Article
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Sabina SaccomannoSabina Saccomanno
Sabina Saccomanno
SSStefano Saran
Stefano Saran
LPLicia Coceani Paskay
Licia Coceani Paskay
NGNicola Giannotta
Nicola Giannotta
RMRodolfo Francesco Mastrapasqua
Rodolfo Francesco Mastrapasqua
FSFabio Scoppa
Fabio Scoppa
Introduction: Scoliosis is a complex three-dimensional malformation of the spine. Although its etiology is still being investigated, it is clear that a number of factors can influence this syndrome. The spinal deformity of idiopathic scoliosis can be viewed from an etiopathogenetic perspective as a symptom of a complicated condition with a multifactorial etiology. Numerous studies have established its relationship with malocclusion, but it is still unclear how these factors interact. Malocclusion is a change in the physiological alignment of the upper and lower teeth that can be either dental or skeletal in origin. This study’s objective is to assess the relationship between scoliosis and malocclusion. Material and Methods: A total of 646 patients were enrolled (554 females and 92 males), 447 with scoliosis and 199 without, from private dental and orthopedic practices, to answer an anonymous questionnaire. They were selected in private dental and orthopedic practices where they had dental and orthopedic examinations. Twenty-two patients were excluded because of a lack of answers. Participants were given a bilingual survey, in English and Italian, composed of 13 questions formulated specifically for this study, using Google Forms (Google LLC, Mountain View, CA, USA). Results: Univariate analysis of the question “Do you have scoliosis?” shows a significant correlation with the following questions: “Was scoliosis a family issue?” (p < 0.05 OR 7.30 IC: 3.05–17.46) “Do you have malocclusion?” (p < 0.05, OR: 1.19 IC:1.0–1.34) and “Was mal-occlusion a family issue?” (p < 0.01, OR: 1.39 IC 1.10–1.77). Performing a multivariate analysis for the same variables, the best predictors of scoliosis were “Was scoliosis a family issue?” (p < 0.001) and “Was malocclusion a family issue?” (p < 0.05), while the question “Do you have malocclusion” lost significance. Conclusion: This study adds further confirmation that there might be an important connection between malocclusion and scoliosis; it suggests that dentists and orthopedists have to check, as early as possible, for the probable presence of both pathologies to avoid a severe progression which, in most cases, may require significant therapy and even surgery.

24 January 2024 in Children
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SSStefano Saran
Stefano Saran
Sabina SaccomannoSabina Saccomanno
Sabina Saccomanno
SVSimonetta Viti
Simonetta Viti
RMRodolfo Francesco Mastrapasqua
Rodolfo Francesco Mastrapasqua
GVGrazia Viti
Grazia Viti
Luca LevriniLuca Levrini
Luca Levrini
Introduction: Obstructive sleep apnea syndrome (OSAS) is a disorder characterized by partial or total airway obstruction during sleep. Studies have shown variability in the level of knowledge and awareness about OSAS among pediatricians. The management of childhood obstructive sleep apnea syndrome (OSAS) depends on the severity of the disease, the presence of comorbidities, and the child’s age. The American Pediatric Academy recommends a multidisciplinary approach involving a pediatrician, a sleep specialist, and an otolaryngologist to provide comprehensive care for children with OSAS. The aim of this cross-sectional study is to evaluate the level of knowledge among pediatricians in Italy regarding the diagnosis of pediatric OSAS. Material and Methods: An anonymized survey was conducted among Italian pediatricians. The survey was administered electronically using Google Forms, and a total of 350 pediatricians were invited to participate. Out of the 350 invitations, 299 pediatricians responded to the survey. The statistical analysis performed consisted of descriptive analysis. The study included 297 pediatricians. Results: Pediatricians demonstrated proficiency in identifying common nocturnal and day symptoms of OSAS. A majority (68.9%) considered the oral and otorhinolaryngologist areas during checkups. Approximately 70.6% took patient weight into account, and 62.8% were aware of the regional diagnostic-therapeutic-assistance pathway. Conclusions: According to the results of this manuscript, there is evidence of a good level of knowledge about OSAS, but disseminating more information about OSAS and all the health issues associated with this syndrome is suggested. This study also has limitations caused by the complexity of the pathology.

15 July 2024 in Dentistry Journal
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Luca LevriniLuca Levrini
Luca Levrini
NGNicola Giannotta
Nicola Giannotta
RMRodolfo Francesco Mastrapasqua
Rodolfo Francesco Mastrapasqua
Davide FarronatoDavide Farronato
Davide Farronato
VMVittorio Maurino
Vittorio Maurino
SSStefano Saran
Stefano Saran
Nowadays, aligners represent a possible therapeutical approach that combines both esthetic and function in order to address dental malocclusion. However, they require a significant level of compliance from the patient. According to the manufacturer, at least 22 h of wearing a day is demanded to reach the optimal therapeutical level; hence, aligners can only be removed during meals. Patients’ compliance might increase and the duration of the treatment might decrease if they were allowed to eat with aligners on. The idea of patients keeping the aligners on during meals has been contemplated, not only to favor patients’ compliance but also treatment effectiveness. This study aims to assess the degree of chewing difficulty that aligners cause when eating certain kinds of food and the quantity of residue left. Material and Methods: A questionnaire titled “Questionnaire for the Assessment of Masticatory Function with Aligners” was administered using Google Forms to 240 patients in treatment with clear aligners. The survey was validated through the reliability test using the test–retest method. This method had a higher correlation coefficient of 0.9 across all items (with a cutoff of 0.8) with statistical significance, and an excellent internal correlation coefficient (α > 0.9). The statistical analysis performed consisted of descriptive analysis, frequencies, percentages, Pearson’s correlation test and Friedman’s test. Results: Pearson’s test showed a statistically significant correlation between all items except between meat or clams and yogurt or ice cream and with mozzarella or soft cheese regarding food chewing difficulties. Pearson’s test showed a statistically significant correlation between all items regarding food residues. A total of 69.2% of the cohort reported some movements of aligners during mastication. In total, 88.3% of them affirmed not to have perceived deformations or breakage of aligners during chewing. Furthermore, 79.2% of them declared that they would continue to eat if eating with aligners was proven to speed up treatment. Conclusions: Wearing clear aligners while chewing foods such as yogurt, ice cream, soft cheese, bread, rice, etc., can be possible and can help shorten the duration of orthodontic treatment, benefiting both the patient and the orthodontist. However, further research using qualitative methods is needed to understand the barriers and facilitators to chewing food with aligners.

Verified
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Luca LevriniLuca Levrini
Luca Levrini
GBGiulia Baldelli
Giulia Baldelli
CCChiara Castellani
Chiara Castellani
LRLuigia Ricci
Luigia Ricci
Claudia DellaviaClaudia Dellavia
Claudia Dellavia
SSStefano Saran
Stefano Saran
This review aims to reveal the effectiveness of myofunctional speech therapy on facial rejuvenation and/or improvement of orofacial function. A systematic review of four medical electronic databases (Medline, Google Scholar, SciELO, and LILACS) was conducted between January and March 2023. The research question was defined using the PICO model: Population (P): adult subjects with signs of physiological aging of facial skin. Intervention (I): aesthetic speech therapy (facial exercises and/or myofunctional therapy). Control (C): absence of treatment. Outcome (O): facial rejuvenation. Through the search process, a total of 472 potentially relevant articles were identified. A total of 21 studies were included in the review. Most of the studies required the participants to perform exercises learned during the weekly session on a daily basis. The subjects underwent an integrated treatment with facial exercises and worked on the stomatognathic functions for different durations. Many differences were found in the evaluation tools used to investigate the starting situation and the effects obtained following the treatment. At the diagnostic level, there was no concordance in the choice of the most appropriate scales and assessment tools, but great heterogeneity was observed. Indeed, forty-eight percent of the studies collected objective data through the use of various instruments (oral devices, electromyographs, cutometers, muscle ultrasound scans, and laser scans of the face). The observed improvements included not only a reduction in wrinkles and frown lines but also decreased muscle tension and slackness, enhanced facial symmetry and lip competence, improved skin elasticity, and restored stomatognathic function. These changes led to myofunctional restoration and facial rejuvenation, resulting in increased satisfaction with self-image and proprioception.

17 October 2025 in Applied Sciences
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Luca LevriniLuca Levrini
Luca Levrini
Vincenzo GiorginoVincenzo Giorgino
Vincenzo Giorgino
NGNicola Giannotta
Nicola Giannotta
ACAndrea Carganico
Andrea Carganico
ADAlessandro Deppieri
Alessandro Deppieri
SSStefano Saran
Stefano Saran
Introduction: Preformed myofunctional appliances are increasingly being studied in orthodontics and are typically used to address oral function anomalies as well as malocclusions and development defects of the jaws. The aim of this study is to evaluate the efficacy of a protocol based on the use of preformed devices and myofunctional therapy for the correction of malocclusions. Materials and Methods: A retrospective study was conducted to evaluate the effectiveness of a preformed myofunctional devices in correcting certain orthodontic problems related to overbite, overjet, and cross-bite. Thirty-six patients in the mixed dentition phase were analyzed along with their clinical records, photos, and scans. Overjet, Overbite, and Crossbite were measured by analyzing the files exported in the Standard Tesselation Language format (Stl) of patients’ arches using Zeiss Inspect® software (version 2025.1.0.1985). Results: The data analysis reveals a statistically significant improvement in the correction of deep bite, overjet, and crossbite. Specifically, regarding the overbite (OVB), the initial measurement at T0 showed an average of 2.52 mm. The average OVB decreased to 1.73 mm at T1. The overjet had an initial average of 3.59 mm at T0, which decreased to 1.77 mm at T1. In this case as well, the difference between the measurements at T0 and T1 was statistically significant. Finally, the crossbite was evaluated by comparing the difference between mandibular and maxillary intermolar widths at T0 and T1. The average difference decreased from 5.84 mm at T0, to 1.68 mm at T1. Conclusions: Preformed myofunctional appliances represent a valid alternative in interceptive orthodontics for correcting and preventing orthodontic issues, especially of mild severity.

17 October 2025 in Dentistry Journal
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Journal Article
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Luca LevriniLuca Levrini
Luca Levrini
Piero Antonio ZeccaPiero Antonio Zecca
Piero Antonio Zecca
VBVirginia Bellora
Virginia Bellora
ADAlessandro Deppieri
Alessandro Deppieri
SSStefano Saran
Stefano Saran
ACAndrea Carganico
Andrea Carganico
Background: This study aimed to evaluate the effectiveness of xylitol- and fluoride-containing chewing gum in reducing dental plaque using a novel 3D colorimetric analysis, and to compare results with the Plaque Control Record (PCR). Methods: An acute intervention study was conducted on 34 healthy adults (18–45 years). A plaque-disclosing solution was applied, and intraoral scans were taken before and after 15 min of gum mastication. Plaque was quantified with PCR and the Placca Read software, which analyzes colorimetric patterns of scanned images. Statistical analyses (Shapiro–Wilk test, paired t-test) were performed with Jamovi Software version 1.6.14. Results: A significant reduction in plaque scores was observed after chewing gum (p < 0.05). Mean reduction reached −14.8% in the experimental group versus −3.9% in controls, where natural saliva flow and pigment washout may explain the modest decline. The 3D analysis provided precise measurements across all dental surfaces and showed strong correlation with PCR, supporting its validity. Conclusions: These findings indicate that functional chewing gum can significantly reduce plaque accumulation even after a single use, and that 3D colorimetric analysis offers a reliable, comprehensive alternative to conventional indices.