Carmen Simal

Department of Chemistry, University of Patras, Rio, Greece

Carmen Simal

Department of Chemistry, University of Patras, Rio, Greece

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Academic Career Length

21Years (2006-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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8 February 2011 in Journal of the American Chemical Society

Journal Article

Organocatalytic Functionalization of Carboxylic Acids: Isothiourea-Catalyzed Asymmetric Intra- and Intermolecular Michael Addition−Lactonizations

Dorine Belmessieri

Louis Morrill

Carmen Simal

Alexandra M. Z. Slawin

Andrew David Smith

1 March 2013 in Chemical Science

Journal Article

Anhydrides as α,β-unsaturated acyl ammonium precursors: isothiourea-promoted catalytic asymmetric annulation processes

Emily R. T. Robinson

Charlene Fallan

Carmen Simal

Alexandra M. Z. Slawin

Andrew David Smith

The asymmetric annulation of a range of α,β-unsaturated acyl ammonium intermediates, formed from isothiourea HBTM 2.1 and anhydrides with either 1,3-dicarbonyls, β-ketoesters or azaaryl ketones gives either functionalised esters (upon ring opening), dihydropyranones or dihydropyridones in good yields (up to 93%) and high enantioselectivity (up to 97% ee).