Alzheimer’s disease (AD) is a complex, progressive neurodegenerative disorder. The subtle and insidious onset of its pathogenesis makes early detection of a formidable challenge in both contemporary neuroscience and clinical practice. In this study, we introduce an advanced diagnostic methodology rooted in the Med-3D transfer model and enhanced with an attention mechanism. We aim to improve the precision of AD diagnosis and facilitate its early identification. Initially, we employ a spatial normalization technique to address challenges like clarity degradation and unsaturation, which are commonly observed in imaging datasets. Subsequently, an attention mechanism is incorporated to selectively focus on the salient features within the imaging data. Building upon this foundation, we present the novel Med-3D transfer model, designed to further elucidate and amplify the intricate features associated with AD pathogenesis. Our proposed model has demonstrated promising results, achieving a classification accuracy of 92%. To emphasize the robustness and practicality of our approach, we introduce an adaptive ‘hot-updating’ auxiliary diagnostic system. This system not only enables continuous model training and optimization but also provides a dynamic platform to meet the real-time diagnostic and therapeutic demands of AD.
Traditional magnetorheological elastomers (MREs) often suffer from limited modulus tunability and insufficient energy dissipation, which restrict their applications. This study prepared a novel composite material by an MR gel (MRG) embedded within the MRE, called the MRE encapsulating MRG, to synergistically enhance these properties. Annular and radial MRE encapsulating MRG configurations were fabricated using 3D-printed molds, and their dynamic mechanical performance was characterized under varying magnetic fields (0–1 T) via a rheometer. The results revealed that the composite materials demonstrated significantly improved magnetic-induced modulus and magnetorheological (MR) effects compared to conventional MREs. Specifically, the annular MRE encapsulating MRG exhibited a 238.47% increase in the MR effect and a 51.35% enhancement in the magnetic-induced modulus compared to traditional MREs. Correspondingly, the radial configuration showed respective improvements of 168.19% and 27.03%. Furthermore, both the annular and radial composites displayed superior energy dissipation capabilities, with loss factors 2.68 and 2.03 times greater than those of pure MREs, respectively. Dynamic response tests indicated that composite materials, particularly the annular MRE encapsulating MRG, achieve faster response times. These advancements highlight the composite’s potential for high-precision damping systems, vibration isolation, and adaptive control applications.