Isheeta Madeka

Dr. Isheeta Madeka


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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6 October 2023 in Surgical Endoscopy
Verified
Journal Article
Closed access
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IMIsheeta Madeka
Isheeta Madeka
KPKeyur Patel
Keyur Patel
PAPeter Altshuler
Peter Altshuler
AIAmrita Iyer
Amrita Iyer
SDSonali Dukle
Sonali Dukle
AKAnirudh Kohli
Anirudh Kohli

14 December 2023 in Journal of Clinical Medicine
Verified
Journal Article
Open access
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IMIsheeta Madeka
Isheeta Madeka
SASneha Alaparthi
Sneha Alaparthi
MMMarisa Moreta
Marisa Moreta
SPShawn Peterson
Shawn Peterson
JMJeffrey Mojica
Jeffrey Mojica
OOOlugbenga Okusanya
Olugbenga Okusanya
Slipping rib syndrome (SRS) is a disorder that occurs when one or more of the eighth through tenth ribs become abnormally mobile. SRS is a poorly understood condition leading to a significant delay in diagnosis and therapeutic management. History and a physical exam are usually sufficient for a diagnosis of SRS. The utility of dynamic ultrasounds has also been studied as a useful diagnostic tool. Multiple surgical techniques for SRS have been described within the literature. Cartilage rib excision (CRE) has been the most common technique utilized. However, the literature has shown a high rate of recurrence and associated risks with the procedure. More recently, minimally invasive rib fixation and costal cartilage excision with vertical rib plating have been shown as successful and safe alternative techniques. This may be an effective, alternative approach to CRE in adult and pediatric populations with SRS.

22 July 2025 in World Journal of Surgical Oncology
Verified
Journal Article
Open access
PDF file
IMIsheeta Madeka
Isheeta Madeka
SYSteven Yi
Steven Yi
JEJulia Evans
Julia Evans
DBDavid Baek
David Baek
HNHaresh V. Naringrekar
Haresh V. Naringrekar
WBWilbur B. Bowne
Wilbur B. Bowne
Background: Pancreatic enucleation is a parenchymal-sparing procedure used for highly select patients with pancreatic neoplasms. We aim to utilize a multi-institutional health research network platform (TriNetX) and a single, high-volume center to assess complications and identify risk factors associated with post-operative pancreatic fistulas (POPF) after pancreatic enucleation. Methods: A two-tiered retrospective study was conducted. We identified 423 patients from TriNetX, and 34 patients from a single-institution IRB-approved database who underwent pancreatic enucleation between 2004–2025 and 2012–2023, respectively. Univariate and multivariate analyses were performed to determine risk factors associated with post-operative complications and occurrence of POPFs. Results: In the TriNetX cohort, 128 (30.3%) experienced postoperative complications after pancreatic enucleation. On univariate analysis, hyperlipidemia (HLD) (OR = 2.37), gastroesophageal reflux disease (GERD) (OR = 3.87), acute pancreatitis (OR = 8.28), chronic pancreatitis (OR = 4.76), nicotine dependence (OR = 2.36), ascites (OR = 6.49), deep vein thrombosis (DVT), pulmonary embolism (PE), and thrombophlebitis (OR = 2.95), and body mass index (BMI) ≥ 25 (OR = 1.56) were identified as significant risk factors. On multivariate analysis, acute pancreatitis (HR = 1.64), chronic pancreatitis (HR = 1.78), ascites (HR = 2.96), DVT, PE and thrombophlebitis (HR = 1.74) remained significant. In our single-institution enucleation cohort, 8 patients had a POPF (23.5%). The measured distance from the neoplasm to the main pancreatic duct (MPD) was significantly shorter in patients who developed POPF (2.8 vs 6.5 mm, P < 0.05). ROC analysis determined that shorter distance from the MPD was predictive of POPF occurrence (AUC = 0.79, p < 0.005). Increased estimated blood loss was also associated with POPF (p < 0.01). Conclusion: Our study identifies clinicopathologic risk factors associated with post-operative complications and POPF after pancreatic enucleation. The distance from the neoplasm to the MPD appears to be a key component of decision-making in the development of POPF.

1 August 2021 in Gynecologic Oncology
Verified
Journal Article
Closed access
DSDavid Shalowitz
David Shalowitz
IMIsheeta Madeka
Isheeta Madeka
JEJoni Evans
Joni Evans
CBCourtney Bailey
Courtney Bailey
KBKristen Bartucci
Kristen Bartucci
JWJohn Wallbillich
John Wallbillich

1 July 2025 in Journal of Thoracic Disease
Verified
Journal Article
Open access
PDF file
IMIsheeta Madeka
Isheeta Madeka
KNKhaled Noueihed
Khaled Noueihed
SASneha Alaparthi
Sneha Alaparthi
JRJohannes B. Roedl
Johannes B. Roedl
SPShawn M. Peterson
Shawn M. Peterson
OOOlugbenga T. Okusanya
Olugbenga T. Okusanya
Background: Diagnostic, therapeutic and surgical techniques for slipping rib syndrome (SRS) are evolving to improve clinical outcomes and recurrence. Our objective was to evaluate current practice patterns in SRS diagnosis and treatment among surgeons nationally. Methods: An electronic survey was nationally distributed to surgeons who were identified as slipped rib repair providers to assess trends in diagnosis and treatment. Descriptive analyses were performed. Results: Twenty-four surgeons responded to the survey (45.3%). Almost half identified as thoracic surgeons (47.6%, n=10); 23.8% identified as pediatric surgeons (n=5), 23.8% as trauma/acute care surgeons (n=5), and 4.8% as general surgeons (n=1). Patient history (54.2%, n=13) and physical exam (70.8%, n=17) were reported as most important diagnostic factors. Of surgeons who utilized preoperative and intraoperative pain regimens, rib blocks with lidocaine were the most common (92.9%, n=13). Suturing of ribs/cartilage was identified as the most integral step in the slipped rib repair operation (70.8%, n=17), followed by excision of rib cartilage (66.7%, n=16), use of a biodegradable plate (54.2%, n=13) and utilizing excised rib cartilage as a spacer (29.2%, n=7). Trauma or inciting event was reported as a positive prognostic factor for post-operative pain relief (82.6%, n=19). Connective tissue disorder (58.3%, n=14) and hypermobility disorder (45.8%, n=11) were identified as the two most common factors associated with recurrence. Conclusions: This national survey of surgeons demonstrates high variability in management and expected outcomes related to diagnosis and treatment for SRS. Further research is needed to identify optimal patient selection and operative approach and long-term clinical outcomes.

26 July 2025 in Journal of Surgical Research
Verified
Journal Article
Closed access
IMIsheeta Madeka
Isheeta Madeka
AHAnnie Ho
Annie Ho
HRHamza Rshaidat
Hamza Rshaidat
SASneha Alaparthi
Sneha Alaparthi
GWGregory L. Whitehorn
Gregory L. Whitehorn
OOOlugbenga T. Okusanya
Olugbenga T. Okusanya