Defne Gunes Ergi

Dr. Defne Gunes Ergi


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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7 September 2021 in ASAIO Journal
Verified
Journal Article
Closed access
AGAnder Dorken Gallastegi
Ander Dorken Gallastegi
DEDefne Gunes Ergi
Defne Gunes Ergi
ÜKÜmit Kahraman
Ümit Kahraman
BYBurcu Yagmur
Burcu Yagmur
EÇEce Çinar
Ece Çinar
MÖMustafa Özbaran
Mustafa Özbaran
Cardiopulmonary exercise test (CPET) parameters are established prognosticators in heart failure. However, the prognostic value of preimplantation and postimplantation CPET parameters in left ventricular assist device (LVAD) therapy is unclear and it is evaluated in this study. Adult patients who were implanted with an LVAD and underwent CPET during the preimplantation or postimplantation period were retrospectively analyzed. Five CPET parameters were calculated: vO2 max, oxygen uptake efficiency slope (OUES), VE/vCO2 Slope, VE/vCO2 min, and VE/vCO2 max. The relationship between CPET parameters and postimplantation outcomes was evaluated with multivariable analysis. Pre and postimplantation CPET cohorts included 191 and 122 patients, respectively. Among preimplantation CPET parameters: vO2 max and OUES were associated with 1, 3, and 5 year mortality, VE/vCO2 min was associated with 3 and 5 year mortality, whereas VE/vCO2 Slope was associated with 5 year mortality. From postimplantation CPET parameters: vO2 max was an independent predictor of 3 and 5 year mortality, whereas VE/vCO2 max was an independent predictor of 3 year mortality following LVAD implantation. Preimplantation CPET parameters have a prognostic value for long-term survival following LVAD implantation, whereas their association with early postimplantation outcomes appears to be weaker. Postimplantation vO2 max and VE/vCO2 max values are associated with survival on device support and may provide a second chance for prognostication in patients without preimplantation CPET data.

22 April 2024 in The Annals of Thoracic Surgery
Verified
Journal Article
Closed access
DEDefne Gunes Ergi
Defne Gunes Ergi
PRPhillip G. Rowse
Phillip G. Rowse
RDRichard C. Daly
Richard C. Daly
JCJuan A. Crestanello
Juan A. Crestanello
HSHartzell V. Schaff
Hartzell V. Schaff
AAArman Arghami
Arman Arghami

22 August 2024 in The Annals of Thoracic Surgery
Verified
Journal Article
Closed access
DEDefne Gunes Ergi
Defne Gunes Ergi
KKKyle W. Klarich
Kyle W. Klarich
JMJoseph J. Maleszewski
Joseph J. Maleszewski
JCJ. Aidan Carney
J. Aidan Carney
PRPhillip G. Rowse
Phillip G. Rowse
AAArman Arghami
Arman Arghami

6 December 2023 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
DEDefne Gunes Ergi
Defne Gunes Ergi
KKKyle W. Klarich
Kyle W. Klarich
JDJoseph A. Dearani
Joseph A. Dearani
JCJuan Antonio Crestanello
Juan Antonio Crestanello
JMJoseph J. Maleszewski
Joseph J. Maleszewski
AAArman Arghami
Arman Arghami
Hepatocellular carcinoma (HCC), constituting the predominant manifestation of liver cancer, stands as a formidable medical challenge. The prognosis subsequent to surgical intervention, particularly for individuals presenting with a solitary tumor, relies heavily on the degree of invasiveness. The decision-making process surrounding therapeutic modalities in such cases assumes paramount importance. This case report illuminates a rather unusual clinical scenario. Here, we encounter a patient who, following a disease-free interval, manifested an atypical presentation of HCC, specifically, a solitary cardiac metastasis. The temporal interval of remission adds an additional layer of complexity to the case. Through a multidisciplinary planning process, the decision was made for surgical removal of the metastatic tumor.

26 April 2023 in Transplantation Proceedings
Verified
Journal Article
Closed access
DEDefne Gunes Ergi
Defne Gunes Ergi
UKUmit Kahraman
Umit Kahraman
OBOzlem Balcioglu
Ozlem Balcioglu
BYBurcu Yagmur
Burcu Yagmur
TYTahir Yagdi
Tahir Yagdi
MOMustafa Ozbaran
Mustafa Ozbaran

17 July 2025 in Journal of Vascular Surgery Cases, Innovations and Techniques
Verified
Journal Article
Open access
DEDefne Gunes Ergi
Defne Gunes Ergi
AAAnil Ziya Apaydin
Anil Ziya Apaydin
HPHakan Posacioglu
Hakan Posacioglu
Abdominal aortic aneurysms represent a health challenge, particularly among older adults. In certain cases, surgical repair necessitates reconstruction of the renal artery. Various techniques are employed for this purpose, including Carrel patch reimplantation, synthetic graft interposition, aortorenal endarterectomy during aortic graft implantation, and the use of covered, self-expandable Viabahn stent grafts. Although the efficacy and safety of Viabahn stent grafts are well-established in endovascular settings, their application in open surgical procedures remains a novel and less common approach. Here, we discuss three cases where the self-expandable Viabahn stent graft was successfully utilized as a bailout technique to preserve renal function, addressing an unexpected need for renal artery revascularization during open suprarenal aortic aneurysm repair.