Henan Xu

Henan Xu


Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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28 June 2024 in Medicine
Verified
Journal Article
Open access
HXHenan Xu
Henan Xu
KYKai Yu
Kai Yu
DWDaguang Wang
Daguang Wang
WWWenjun Ds Wang
Wenjun Ds Wang
LRLi Rong
Li Rong
GCGuang Chen
Guang Chen
Rationale: Thyroglossal duct carcinoma, a rare clinical condition characterized by ectopic thyroid adenocarcinoma within thyroglossal duct cysts (TGDCs), typically confirmed through intraoperative rapid pathology, this condition generally has a favorable prognosis. Nevertheless, comprehensive treatment guidelines across all disease stages are lacking, the purpose of this study is to report 1 case of the disease and propose the treatment plan for each stage of the disease. Patient concerns: A patient presented with thyroid swelling, classified as C-TIRADS 4A following a physical examination. Preoperative thyroid puncture identified papillary thyroid carcinoma, and genetic testing revealed a BRAF gene exon 15-point mutation. Ancillary tests showed a slightly decreased thyroid stimulating hormone (TSH) level (0.172) with no other significant abnormalities. Diagnoses: Preoperative fine-needle aspiration cytology (FNAC) confirmed right-side thyroid cancer. Intraoperative exploration uncovered a TGDC and intraoperative rapid pathology confirmed thyroglossal duct carcinoma. Interventions: A Sistrunk operation and ipsilateral thyroidectomy were performed. Outcomes: Postoperative recovery was satisfactory. Lessons: Thyroglossal duct carcinoma is a rare disease affecting the neck. Due to limited clinical cases and the favorable prognosis associated with this condition, there is currently no established set of diagnostic and treatment guidelines. According to tumor size, lymph node metastasis, thyroid status and other factors, the corresponding treatment methods were established for each stage of thyroglossal duct cancer, which laid the foundation for the subsequent treatment development of this disease.

6 October 2023 in Medicine
Verified
Journal Article
Open access
KYKai Yu
Kai Yu
LHLei Hao
Lei Hao
HXHenan Xu
Henan Xu
YGYuanzhi Guo
Yuanzhi Guo
YDYaqi Duan
Yaqi Duan
PLPeng Li
Peng Li
This paper implements a bibliometric approach to investigate the research hotspots and future research directions in the relevant field literature. It also offers research ideas and methods for preventing and treating cognitive impairment induced by sleep deprivation in the clinical setting. The evolution of various clusters in the field is summarized through Citespace’s projection function for keywords in the literature. CiteSpace and Vosviewer are utilized to analyze and visualize the attributes of the articles, including number of publications, citation frequency, country/region, institution, journal, authors, keywords, and references, from the 2280 publications obtained. A total of 2280 publications were collected, with the number of papers and citations in the field continuously increasing year by year. The most influential country in this field is the United States, and the University of Washington is the most influential institution. The most authoritative journal in the field is identified as SLEEP. Sleep deprivation, prefrontal cortex, and performance are the current topics of interest. The article with the strongest citation burst, lasting from 2015 to 2018, is “Sleep Drives Metabolite Clearance from the Adult Brain.” The most influential article and co-cited reference, “Neurocognitive Consequences of Sleep Deprivation,” highlights that sleep deprivation from various causes may lead to cognitive impairment. Future research should investigate all forms of cognitive impairment resulting from sleep deprivation. The findings of this study will assist researchers in improving their knowledge structure, identifying research hotspots, and revealing future directions in the field.

7 March 2025 in Medicine
Verified
Journal Article
Open access
HXHenan Xu
Henan Xu
KYKai Yu
Kai Yu
JWJinnan Ds Wang
Jinnan Ds Wang
LRLi Ds Rong
Li Ds Rong
QLQiaoyu Ds Li
Qiaoyu Ds Li
The skin’s integrity is vulnerable to external elements that can induce injuries, leading to wound formation. It’s crucial to comprehend wound healing processes to protect the body when this protective barrier is compromised. Over the last 2 decades, there has been considerable progress in understanding delayed wound healing, with a focus on the mechanisms and microenvironmental factors involved. The connection between oxidative stress and wound healing has recently gained attention, emphasizing the need for in-depth analysis to propel further advancements and interventions in this area. Despite these advancements, there remains a noticeable void in the literature concerning the application of scientometric methods to systematically examine the progression of wound healing research. Additionally, a comprehensive assessment of the research output and effectiveness of various researchers and institutions in this field is lacking. To address these gaps, we analyzed data from the Web of Science Core Collection from January 1, 2000, to December 31, 2023, utilizing relevant keywords. Using CiteSpace, we created visual maps that depict the evolution and structure of keyword clusters, and both CiteSpace and VOSviewer were used to evaluate the performance of research networks across different countries, institutions, and authors. This data was methodically analyzed. The leading institution in this field is the Chinese Academy of Medical Sciences. The key researchers are Bekeschus, Sander; Li, Yang; Bi, Yang; Fan, Daidi; and Zhang, Yu. Our software analysis reviewed 3025 studies, revealing 19 co-citation clusters that highlight current trends in research on oxidative stress and wound healing. Prominent journals, leading institutions, and key researchers were identified. Key emerging research directions include studying the mechanisms linking oxidative stress to wound healing, exploring the use of antioxidant substances in wound dressings, and investigating how nanomaterials in dressings can influence oxidative stress. These focal points emphasize the significance of understanding oxidative stress’s impact on wound healing and investigating new methods to enhance therapeutic efficacy. This comprehensive approach not only fills a gap in the current literature but also sets the stage for future research endeavors in this crucial area of health science.