Fan Yang

Dr. Fan Yang


Research Focus & Metrics

Academic Career Length

18Years (2009-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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3 February 2016 in BMC Bioinformatics
Verified
Journal Article
Open access
PDF file
HWHuazhen Wang
Huazhen Wang
FYFan Yang
Fan Yang
ZLZhiyuan Luo
Zhiyuan Luo
Background: The stability of Variable Importance Measures (VIMs) based on random forest has recently received increased attention. Despite the extensive attention on traditional stability of data perturbations or parameter variations, few studies include influences coming from the intrinsic randomness in generating VIMs, i.e. bagging, randomization and permutation. To address these influences, in this paper we introduce a new concept of intrinsic stability of VIMs, which is defined as the self-consistence among feature rankings in repeated runs of VIMs without data perturbations and parameter variations. Two widely used VIMs, i.e., Mean Decrease Accuracy (MDA) and Mean Decrease Gini (MDG) are comprehensively investigated. The motivation of this study is two-fold. First, we empirically verify the prevalence of intrinsic stability of VIMs over many real-world datasets to highlight that the instability of VIMs does not originate exclusively from data perturbations or parameter variations, but also stems from the intrinsic randomness of VIMs. Second, through Spearman and Pearson tests we comprehensively investigate how different factors influence the intrinsic stability. Results: The experiments are carried out on 19 benchmark datasets with diverse characteristics, including 10 high-dimensional and small-sample gene expression datasets. Experimental results demonstrate the prevalence of intrinsic stability of VIMs. Spearman and Pearson tests on the correlations between intrinsic stability and different factors show that #feature (number of features) and #sample (size of sample) have a coupling effect on the intrinsic stability. The synthetic indictor, #feature/#sample, shows both negative monotonic correlation and negative linear correlation with the intrinsic stability, while OOB accuracy has monotonic correlations with intrinsic stability. This indicates that high-dimensional, small-sample and high complexity datasets may suffer more from intrinsic instability of VIMs. Furthermore, with respect to parameter settings of random forest, a large number of trees is preferred. No significant correlations can be seen between intrinsic stability and other factors. Finally, the magnitude of intrinsic stability is always smaller than that of traditional stability. Conclusion: First, the prevalence of intrinsic stability of VIMs demonstrates that the instability of VIMs not only comes from data perturbations or parameter variations, but also stems from the intrinsic randomness of VIMs. This finding gives a better understanding of VIM stability, and may help reduce the instability of VIMs. Second, by investigating the potential factors of intrinsic stability, users would be more aware of the risks and hence more careful when using VIMs, especially on high-dimensional, small-sample and high complexity datasets.

30 January 2009 in BMC Bioinformatics
Verified
Journal Article
Open access
PDF file
FYFan Yang
Fan Yang
HWHua-Zhen Wang
Hua-Zhen Wang
HMHong Mi
Hong Mi
CLCheng-De Lin
Cheng-De Lin
WCWei-Wen Cai
Wei-Wen Cai
Background: Most machine-learning classifiers output label predictions for new instances without indicating how reliable the predictions are. The applicability of these classifiers is limited in critical domains where incorrect predictions have serious consequences, like medical diagnosis. Further, the default assumption of equal misclassification costs is most likely violated in medical diagnosis. Results: In this paper, we present a modified random forest classifier which is incorporated into the conformal predictor scheme. A conformal predictor is a transductive learning scheme, using Kolmogorov complexity to test the randomness of a particular sample with respect to the training sets. Our method show well-calibrated property that the performance can be set prior to classification and the accurate rate is exactly equal to the predefined confidence level. Further, to address the cost sensitive problem, we extend our method to a label-conditional predictor which takes into account different costs for misclassifications in different class and allows different confidence level to be specified for each class. Intensive experiments on benchmark datasets and real world applications show the resultant classifier is well-calibrated and able to control the specific risk of different class. Conclusion: The method of using RF outlier measure to design a nonconformity measure benefits the resultant predictor. Further, a label-conditional classifier is developed and turn to be an alternative approach to the cost sensitive learning problem that relies on label-wise predefined confidence level. The target of minimizing the risk of misclassification is achieved by specifying the different confidence level for different class.

11 June 2014 in PLOS ONE
Verified
Journal Article
Open access
PDF file
HWHuazhen Wang
Huazhen Wang
XLXin Liu
Xin Liu
BLBing Lv
Bing Lv
FYFan Yang
Fan Yang
YHYanzhu Hong
Yanzhu Hong
Chronic Fatigue (CF) still remains unclear about its etiology, pathophysiology, nomenclature and diagnostic criteria in the medical community. Traditional Chinese medicine (TCM) adopts a unique diagnostic method, namely ‘bian zheng lun zhi’ or syndrome differentiation, to diagnose the CF with a set of syndrome factors, which can be regarded as the Multi-Label Learning (MLL) problem in the machine learning literature. To obtain an effective and reliable diagnostic tool, we use Conformal Predictor (CP), Random Forest (RF) and Problem Transformation method (PT) for the syndrome differentiation of CF. In this work, using PT method, CP-RF is extended to handle MLL problem. CP-RF applies RF to measure the confidence level (p-value) of each label being the true label, and then selects multiple labels whose p-values are larger than the pre-defined significance level as the region prediction. In this paper, we compare the proposed CP-RF with typical CP-NBC(Naïve Bayes Classifier), CP-KNN(K-Nearest Neighbors) and ML-KNN on CF dataset, which consists of 736 cases. Specifically, 95 symptoms are used to identify CF, and four syndrome factors are employed in the syndrome differentiation, including ‘spleen deficiency’, ‘heart deficiency’, ‘liver stagnation’ and ‘qi deficiency’. CP-RF demonstrates an outstanding performance beyond CP-NBC, CP-KNN and ML-KNN under the general metrics of subset accuracy, hamming loss, one-error, coverage, ranking loss and average precision. Furthermore, the performance of CP-RF remains steady at the large scale of confidence levels from 80% to 100%, which indicates its robustness to the threshold determination. In addition, the confidence evaluation provided by CP is valid and well-calibrated. CP-RF not only offers outstanding performance but also provides valid confidence evaluation for the CF syndrome differentiation. It would be well applicable to TCM practitioners and facilitate the utilities of objective, effective and reliable computer-based diagnosis tool.

24 April 2024 in Heliyon
Verified
Journal Article
Open access
BHBinsheng Hong
Binsheng Hong
PLPing Lu
Ping Lu
HXHang Xu
Hang Xu
JLJiangtao Lu
Jiangtao Lu
KLKaibiao Lin
Kaibiao Lin
FYFan Yang
Fan Yang
Health insurance fraud is becoming more common and impacting the fairness and sustainability of the health insurance system. Traditional health insurance fraud detection primarily relies on recognizing established data patterns. However, with the ever-expanding and complex nature of health insurance data, it is difficult for these traditional methods to effectively capture evolving fraudulent activity and tactics and keep pace with the constant improvements and innovations of fraudsters. As a result, there is an urgent need for more accurate and flexible analytics to detect potential fraud. To address this, the Multi-channel Heterogeneous Graph Structured Learning-based health insurance fraud detection method (MHGSL) was proposed. MHGSL constructs a graph of health insurance data from various entities, such as patients, departments, and medicines, and employs graph structure learning to extract topological structure, features, and semantic information to construct multiple graphs that reflect the diversity and complexity of the data. We utilize deep learning methods such as heterogeneous graph neural networks and graph convolutional neural networks to combine multi-channel information transfer and feature fusion to detect anomalies in health insurance data. The results of extensive experiments on real health insurance data demonstrate that MHGSL achieves a high level of accuracy in detecting potential fraud, which is better than existing methods, and is able to quickly and accurately identify patients with fraudulent behaviors to avoid loss of health insurance funds. Experiments have shown that multi-channel heterogeneous graph structure learning in MHGSL can be very helpful for health insurance fraud detection. It provides a promising solution for detecting health insurance fraud and improving the fairness and sustainability of the health insurance system. Subsequent research on fraud detection methods can consider semantic information between patients and different types of entities.

8 February 2022 in IEEE Transactions on Intelligent Transportation Systems
Verified
Journal Article
Closed access
YLYongxuan Lai
Yongxuan Lai
YXYifan Xu
Yifan Xu
DMDuojian Mai
Duojian Mai
YFYi Fan
Yi Fan
FYFan Yang
Fan Yang
Modern vehicles are gradually becoming powerful mobile sensing, communication, computing and storage platforms, which bring about the concept of vehicular urban sensing that leverages sensor nodes as an effective and affordable solution for large-scale and fine-grained sensing. And there is a trend to combine the vehicular sensing and outsourcing technologies to solve the large-scale urban road sensing problem. However, how to select appropriate participated vehicles, how to least interrupt the original routes of vehicles, and how to actively maximize the benefit of the sensing remain challenging problems. In this paper, we introduce a Crowdsourced Vehicular Sensing (CVS) framework based on more realistic assumptions of the vehicular sensing, which consists of three steps: vehicle recruitment, candidate path calculation, and path computing. We define a maximal weighted sensing paths (MWSP) problem, which is NP-Complete, in vehicular crowdsensing scenario and use heuristic methods to speed up the solving process for large-scale crowdsensing in urban road networks. The MWSP problem is formulated as a maximal satisfiability (MaxSAT) problem, and a least-interrupted urban sensing strategy is adopted. So trips are least disrupted when conducting the sensing tasks, which would increase the drivers’ willingness to participate in urban sensing. Experiments based on real-world road-network and historical origin-destination datasets verify the effectiveness of the proposed method. The results show that the proposed algorithm outperforms other solutions and it can solve the vehicular crowdsensing problem effectively and efficiently.

29 December 2017 in Sensors
Verified
Journal Article
Open access
PDF file
YLYongxuan Lai
Yongxuan Lai
FYFan Yang
Fan Yang
JSJinsong Su
Jinsong Su
QZQifeng Zhou
Qifeng Zhou
Tian WangTian Wang
Tian Wang
YXYifan Xu
Yifan Xu
Vehicular nodes are equipped with more and more sensing units, and a large amount of sensing data is generated. Recently, more and more research considers cooperative urban sensing as the heart of intelligent and green city traffic management. The key components of the platform will be a combination of a pervasive vehicular sensing system, as well as a central control and analysis system, where data-gathering is a fundamental component. However, the data-gathering and monitoring are also challenging issues in vehicular sensor networks because of the large amount of data and the dynamic nature of the network. In this paper, we propose an efficient continuous event-monitoring and data-gathering framework based on fog nodes in vehicular sensor networks. A fog-based two-level threshold strategy is adopted to suppress unnecessary data upload and transmissions. In the monitoring phase, nodes sense the environment in low cost sensing mode and generate sensed data. When the probability of the event is high and exceeds some threshold, nodes transfer to the event-checking phase, and some nodes would be selected to transfer to the deep sensing mode to generate more accurate data of the environment. Furthermore, it adaptively adjusts the threshold to upload a suitable amount of data for decision making, while at the same time suppressing unnecessary message transmissions. Simulation results showed that the proposed scheme could reduce more than 84 percent of the data transmissions compared with other existing algorithms, while it detects the events and gathers the event data.