Background: Pain assessment and management are important in postoperative circumstances as overdosing of opioids can induce respiratory depression and critical consequences. We aimed this study to check the reliability of commonly used pain scales in a postoperative setting among Korean adults. We also intended to determine cut-off points of pain scores between mild and moderate pain and between moderate and severe pain by which can help to decide to use pain medication. Methods: A total of 180 adult patients undergoing elective non-cardiac surgery were included. Postoperative pain intensity was rated with a visual analog scale (VAS), numeric rating scale (NRS), faces pain scale revised (FPS-R), and verbal rating scale (VRS). The VRS rated pain according to four grades: none, mild, moderate, and severe. Pain assessments were performed twice: when the patients were alert enough to communicate after arrival at the postoperative care unit (PACU) and 30 min after arrival at the PACU. The levels of agreement among the scores were evaluated using intraclass correlation coefficients (ICCs). The cut-off points were determined by receiver operating characteristic curves. Results: The ICCs among the VAS, NRS, and FPS-R were consistently high (0.839–0.945). The pain categories were as follow: mild ≦ 5.3 / moderate 5.4 ~ 7.1 /severe ≧ 7.2 in VAS, mild ≦ 5 / moderate 6 ~ 7 / severe ≧ 8 in NRS, mild ≦ 4 / moderate 6 / severe 8 and 10 in FPS-R. The cut-off points for analgesics request were VAS ≧ 5.5, NRS ≧ 6, FPS-R ≧ 6, and VRS ≧ 2 (moderate or severe pain). Conclusions: During the immediate postoperative period, VAS, NRS, and FPS-R were well correlated. The boundary between mild and moderate pain was around five on 10-point scales, and it corresponded to the cut-off point of analgesic request. Healthcare providers should consider VRS and other patient-specific signs to avoid undertreatment of pain or overdosing of pain medication.

Cho S, et al. J Korean Surg Soc. 2013 Sep;85(3):128-133. http://dx.doi.org/10.4174/jkss.2013.85.3.128

Cho S, et al. J Korean Med Sci. 2020 Mar;35(17):e113. https://doi.org/10.3346/jkms.2020.35.e113

Background: The decision to discontinue intensive care unit (ICU) treatment during the end-of-life stage has recently become a significant concern in Korea, with an observed increase in life-sustaining treatment (LST) withdrawal. There is a growing demand for evidence-based support for patients, families, and clinicians in making LST decisions. This study aimed to identify factors influencing LST decisions in ICU inpatients and to analyze their impact on healthcare utilization.Methods: In this retrospective study, we examined medical records of ICU patients with neurological disorders, infectious disorders, or cancer who were treated at a single university hospital between January 1, 2019 and July 7, 2021. Factors influencing the decision to withdraw LST were compared between those who withdrew LST and those who did not.Results: Among 54,699 hospital admissions, LST was withdrawn from 550 patients (1%). Cancer was the most common disease, followed by pneumonia, and cerebral infarction. Among patients admitted to the ICU, LST was withdrawn from 215 (withdrawal group). The withdrawal group was older (78 vs. 75 years, P=0.05) and had longer total hospital stays (16 vs. 11 days, P<0.001) and higher ICU readmission rates than control patients (ICU patients for whom LST was not withdrawn). When healthcare costs were compared, there was no significant difference in the cost of ICU stay between the two groups. The family played a crucial role in the LST decision (86% of LST decisions).Conclusions: The decision to withdraw LST of ICU patients was influenced by age, readmission, and disease category. ICU costs were similar for patients who withdrew from LST treatment and those who did not. Further research is need to help patients and families tailor LST decisions in the ICU.

Transcutaneous carbon dioxide (PtcCO₂) monitoring is known to be effective at estimating the arterial partial pressure of carbon dioxide (PaCO₂) in patients with sedation-induced respiratory depression. We aimed to investigate the accuracy of PtcCO₂ monitoring to measure PaCO₂ and its sensitivity to detect hypercapnia (PaCO₂ > 60 mmHg) compared to nasal end-tidal carbon dioxide (PetCO₂) monitoring during non-intubated video-assisted thoracoscopic surgery (VATS). This retrospective study included patients undergoing non-intubated VATS from December 2019 to May 2021. Datasets of PetCO₂, PtcCO₂, and PaCO₂ measured simultaneously were extracted from patient records. Overall, 111 datasets of CO₂ monitoring during one-lung ventilation (OLV) were collected from 43 patients. PtcCO₂ had higher sensitivity and predictive power for hypercapnia during OLV than PetCO₂ (84.6% vs. 15.4%, p < 0.001; area under the receiver operating characteristic curve; 0.912 vs. 0.776, p = 0.002). Moreover, PtcCO₂ was more in agreement with PaCO₂ than PetCO₂, indicated by a lower bias (bias ± standard deviation; −1.6 ± 6.5 mmHg vs. 14.3 ± 8.4 mmHg, p < 0.001) and narrower limit of agreement (−14.3–11.2 mmHg vs. −2.2–30.7 mmHg). These results suggest that concurrent PtcCO₂ monitoring allows anesthesiologists to provide safer respiratory management for patients undergoing non-intubated VATS.

Cho S, et al. J Korean Med Sci. 2020 Sep;35(39):e327. https://doi.org/10.3346/jkms.2020.35.e327