Paulina Świechowska-Starek

Dr. Paulina Świechowska-Starek


Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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2 January 2024 in Nutrients
Verified
Journal Article
Open access
PDF file
MAMonika Abramiuk
Monika Abramiuk
PMPaulina Mertowska
Paulina Mertowska
KFKarolina Frankowska
Karolina Frankowska
PŚPaulina Świechowska-Starek
Paulina Świechowska-Starek
MSMałgorzata Satora
Małgorzata Satora
EGEwelina Grywalska
Ewelina Grywalska
Endometriosis is a chronic, hormone-dependent disease characterized by the presence of endometrial tissue in ectopic locations. Since the treatment options for this disease are still limited, and the cure rate is unsatisfactory, the search for ways to treat symptoms and modify the course of the disease is of key importance in improving the quality of life of patients with endometriosis. So far, the literature has shown that nutrition can influence endometriosis through hormonal modification and altering the inflammatory or oxidative response. Since the importance of nutrition in this disease is still a subject of scientific research, we aimed to summarize the current knowledge on the role of dietary modifications in endometriosis. Our review showed that nutrients with anti-inflammatory and antioxidant properties, including most vitamins and several trace elements, may influence the pathogenesis of endometriosis and can be considered as the nutrients preventing the development of endometriosis. However, despite the many discoveries described in this review, further interdisciplinary research on this topic seems to be extremely important, as in the future, it may result in the development of personalized therapies supporting the treatment of endometriosis.

20 December 2023 in Journal of Personalized Medicine
Verified
Journal Article
Open access
PDF file
KSKonrad Suswał
Konrad Suswał
Michał TomaszewskiMichał Tomaszewski
Michał Tomaszewski
ARAleksandra Romaniuk
Aleksandra Romaniuk
PŚPaulina Świechowska-Starek
Paulina Świechowska-Starek
WZWojciech Zygmunt
Wojciech Zygmunt
MRMałgorzata Romaniuk-Suswał
Małgorzata Romaniuk-Suswał
Recent advancements in the understanding of pulmonary arterial hypertension (PAH) have highlighted the significant role of the gut microbiota (GM) in its pathogenesis. This comprehensive review delves into the intricate relationship between the GM and PAH, emphasizing the influence of gut microbial composition and the critical metabolites produced. We particularly focus on the dynamic interaction between the gut and lung, examining how microbial dysbiosis contributes to PAH development through inflammation, altered immune responses, and changes in the gut–lung axis. Noteworthy findings include variations in the ratios of key bacterial groups such as Firmicutes and Bacteroidetes in PAH and the pivotal roles of metabolites like trimethylamine N-oxide (TMAO), short-chain fatty acids (SCFAs), and serotonin in the disease’s progression. Additionally, the review elucidates potential diagnostic biomarkers and novel therapeutic approaches, including the use of probiotics and fecal microbiota transplantation, which leverage the gut microbiota for managing PAH. This review encapsulates the current state of research in this field, offering insights into the potential of gut microbiota modulation as a promising strategy in PAH diagnosing and treatment.