In recent years, owing to the miniaturization of the fluidic environment, microfluidic technology offers unique opportunities for the implementation of nano drug delivery systems (NDDSs) production processes. Compared with traditional methods, microfluidics improves the controllability and uniformity of NDDSs. The fast mixing and laminar flow properties achieved in the microchannels can tune the physicochemical properties of NDDSs, including particle size, distribution and morphology, resulting in narrow particle size distribution and high drug-loading capacity. The success of lipid nanoparticles encapsulated mRNA vaccines against coronavirus disease 2019 by microfluidics also confirmed its feasibility for scaling up the preparation of NDDSs via parallelization or numbering-up. In this review, we provide a comprehensive summary of microfluidics-based NDDSs, including the fundamentals of microfluidics, microfluidic synthesis of NDDSs, and their industrialization. The challenges of microfluidics-based NDDSs in the current status and the prospects for future development are also discussed. We believe that this review will provide good guidance for microfluidics-based NDDSs.

Upon surface functionalization and stabilization of β-NaYF₄:Yb/Er upconversion nanoparticles (UCNPs) with phosphoryl pillar[5]arenes (PP5) via a facile ligand exchange method, we constructed a new hybrid material (PP5-UCNPs) with good water dispersibility especially in a physiological environment and superior capability of controlled cargo release and cell imaging.

Noncovalent functionalization of carbon nanotubes by wrapping them using π‐conjugated polymers is one of the most promising techniques to sort, separate, and purify semiconducting nanotube species for applications in optoelectronic devices. However, wide energy bandgap polymers commonly used in this technique reduce charge transport through the nanotube network. To avoid the formation of insulating barriers between the tubes, challenging procedures for the removal of the polymer from the nanotube walls are necessary. Here, the use of two narrow bandgap polymers based on naphthalene‐bis(dicarboximide) (NDI), namely, poly{[N,N′‐bis(2‐octyldodecyl)‐naphthalene‐1,4,5,8‐bis(dicarboximide)‐2,6‐diyl]‐alt‐5,59‐(2,29‐bithiophene)}, (P(NDI2OD‐T2 or ActivInk N2200) and its molecular cousin, poly{[(N,N′‐bis(2‐octyldodecyl)‐1,4,5,8‐naphthalenedicarboximide‐2,6‐diyl)‐alt‐5,5′‐(2,2′‐bithiophene)]‐co‐[(N,N′‐bis(2‐octyldodecyl)‐1,4,5,8‐naphthalenedicarboximide‐2,6‐diyl)‐alt‐5,5′‐(2,2′‐(4,4′‐dimethoxybithiophene))]}(ActivInk PE‐N‐73), for selecting semiconducting single‐walled carbon nanotubes (s‐SWNTs) is demonstrated. The influence of the chemical structure of these polymers on the nanotube selectivity, as well as the effect of residual excess polymer and their band‐gaps, are investigated through optical spectroscopy and charge transport measurements. While the electron transport of the devices fabricated with PE‐N‐73 and N2200 wrapped SWNTs is comparable, a substantial difference is observed in the hole transport. The better alignment of the HOMO level of PE‐N‐73 with that of the nanotubes allows achieving improved p‐type characteristics even with a large amount of residual polymer in the network.

In the current data age, the fundamental research related to optical applications has been rapidly developed. Countless new-born materials equipped with distinct optical properties have been widely explored, exhibiting tremendous values in practical applications. The optical data storage technique is one of the most significant topics of the optical applications, which is considered as the prominent solution for conquering the challenge of the explosive increase in mass data, to achieve the long-life, low-energy, and super high-capacity data storage. On this basis, our review outlines the representative reports for mainly introducing the functional systems based on the newly established materials applied in the optical storage field. According to the material categories, the representative functional systems are divided into rare-earth doped nanoparticles, graphene, and diarylethene. In terms of the difference of structural features and delicate properties among the three materials, the application in optical storage is comprehensively illustrated in the review. Meanwhile, the potential opportunities and critical challenges of optical storage are also discussed in detail.