Human Machine Interfaces and biomedical prosthetics are advancing rapidly, merging human and machine capabilities. These innovations offer tremendous benefits, but the effectiveness of implantable medical devices (IMDs) hinges on the reliability of their batteries. This article explores the various battery technologies used to power IMDs. The review focuses on the unique characteristics, identifies current challenges and future opportunities in the design and enhancement of batteries for IMDs. The review delves into different battery technologies, emphasizing advancements in electrode materials, biocompatible electrolytes, innovative power delivery systems, and novel energy harvesting techniques. It explores the potential of incorporating new nanomaterials, wireless charging solutions, and bio-energy harvesting methods in battery design. Furthermore, the review discusses recent progress in AI-powered implantable battery health monitoring. The study identifies key challenges in existing battery technologies, such as issues with energy density, cycling stability, and longevity, and points out possible enhancements facilitated by introducing advanced materials and cutting-edge technologies. The review also highlights the promise of AI techniques in improving the health monitoring of implantable batteries. The review highlights the critical need to address the stringent requirements of implantable battery design to drive the advancement of healthcare technologies. By adopting novel materials, innovative charging, and energy harvesting methods, along with AI-driven health monitoring, substantial improvements in implantable battery performance can be achieved, thereby enhancing the reliability and effectiveness of biomedical prosthetics and implantable devices. Graphical abstract

Need for non-toxic materials especially for biomedical application remains the most important driving force for the discovery of nature-derived biomaterials. In particular, fibers and extracts from plants with medicinal value are vastly investigated. One such source is the banana fiber. The lignocellulosic and protein-based structures of banana fibers contribute to their biodegradability and biocompatibility, which are essential attributes for medical use. Despite their promising biocompatibility, banana fibers face challenges such as variability in their mechanical properties and limited raw state performance. This necessitates precise fiber synthesis and advanced processing to obtain biocompatible fibers for biomedical use. This review discusses the chemical constituents, extraction methods, characterization of natural fiber derived from banana pseudo stem, along with the antimicrobial and tissue regeneration potential of banana fiber based biomedical materials recently developed. Further, steps involved in the conversion of banana fiber to useful biomedical material are presented along with fabrication techniques. In addition, challenges and limitations that hurdle research progress, and potential for future biomaterials through functionalization are discussed. Review findings support potential for research intervention at the integration of banana fibers, biopolymers and nanotechnology towards development of efficient wound healing materials. Inherent to the comprehensive coverage of topics, the authors assure that this review will potentially act as a valuable source of information that could boost research and development of banana fiber-based wound healing biomaterials. Graphical Abstract