Chunbo He

Dr. Chunbo He

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA

Biography

Dr. Chunbo He is a leading figure in anti-tumor research, dedicated to identifying innovative therapeutic targets and improving treatment strategies for malignant tumors. His academic foundation was established under Professor Cheng Wang, where he explored the Hippo/YAP signaling pathway and its implications for cancers such as ovarian and cervical cancer. His esteemed publications span top journals, highlighting his contributions to cancer biology. As a doctoral student and postdoctoral fellow, Dr. He collaborated with prominent scholars to examine how targeted nutrient metabolism can enhance the tumor immune microenvironment, improving the efficacy of immunotherapies. His notable findings include: 1. Discovering that vitamin B6 metabolism fosters pancreatic tumor growth while hindering NK cell-mediated immunity, suggesting a new therapeutic direction for pancreatic cancer. 2. Investigating the regulatory interplay between the Hippo/YAP pathway and HPV, pointing to YAP as a potential target in cervical cancer treatment. 3. Defining the Hippo/YAP pathway's roles in ovarian function and cancer development, advocating for its targeting in both ovarian cancer and certain infertility cases.

Affiliations

University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, USA

Honors and Awards

No honors or awards have been shared yet.

Experience

University Educator/Researcher

OKLAHOMA UNIVERSITY HEALTH SCIENCE CENTER

01 Sep 2023 - present

Post Doctoral Researcher

OKLAHOMA UNIVERSITY HEALTH SCIENCE CENTER

01 May 2022 - 01 Mar 2025

Graduate Student or Post Graduate

UNIVERSITY OF NEBRASKA MEDICAL CENTER

01 Aug 2018 - 01 May 2022