Meike Weis

Dr. Meike Weis

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Research Focus & Metrics

Academic Career Length

12Years (2015-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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13 January 2023 in Pediatric Radiology
Verified
Journal Article
Open access
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ITIlias Tsiflikas
Ilias Tsiflikas
GTGreta Thater
Greta Thater
IAIsabelle Ayx
Isabelle Ayx
JWJakob Weiss
Jakob Weiss
JSJuergen Schaefer
Juergen Schaefer
MWMeike Weis
Meike Weis
Background: With the clinical release of a photon counting detector-based computed tomography (CT) system, the potential benefits of this new technology need to be evaluated clinically. Literature concerning this new generation of detector is sparse, especially in the field of pediatric radiology. Therefore, this study outlines our initial experience with ultra-low dose chest CT imaging on the new photon counting CT system. Materials and methods: A pediatric phantom (1-year old, CIRS ATOM phantom, model 704 [CIRS-computerized imaging reference system, Norfolk, VA]) was scanned at different dose levels and different image quality levels to define a protocol for clinical examinations. Next, 20 consecutive pediatric non-contrast ultra-low dose chest CT examinations were evaluated for radiation dose and diagnostic image quality using a 4-point Likert-scale—1 = excellent, 4 = bad image quality—by two radiologists in a consensus reading. This retrospective analysis was approved by the local research ethics committee. Results: Chest CT examinations performed at ultra-low radiation dose (effective dose 0.19 ± 0.07 mSv; size-specific dose estimate 0.45 ± 0.14 mGy) in pediatric patients ages (2.6 ± 1.8 years) show good to excellent image quality for lung structures (1.4 ± 0.4) and moderate image quality for soft tissue structures (2.8 ± 0.2). Conclusion: Pediatric ultra-low dose chest CT examinations are feasible with the new generation photon counting detector-based CT system. The benefits of this technology must be evaluated for pediatric patients from the outset.

16 April 2019 in Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
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Journal Article
Open access
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TTTom Terboven
Tom Terboven
GLGeorg Leonhard
Georg Leonhard
LWLucas Wessel
Lucas Wessel
TVTim Viergutz
Tim Viergutz
MRMarcus Rudolph
Marcus Rudolph
HHHolger Haubenreisser
Holger Haubenreisser
Recommendations regarding decompression of tension pneumothorax in small children are scarce and mainly transferred from the adult literature without existing evidence for the paediatric population. This CT-based study evaluates chest wall thickness, width of the intercostal space (ICS) and risk of injury to vital structures by needle decompression in children. Chest wall thickness, width of the intercostal space and depth to vital structures were measured and evaluated at 2nd ICS midclavicular (MCL) line and 4th ICS anterior axillary line (AAL) on both sides of the thorax using computed tomography (CT) in 139 children in three different age groups (0, 5, 10 years). Width of the intercostal space was significantly smaller at the 4th ICS compared to the 2nd ICS in all age groups on both sides of the thorax. Chest wall thickness was marginally smaller at the 4th ICS compared to the 2nd ICS in infants and significantly smaller at 4th ICS in children aged 5 years and 10 years. Depth to vital structure for correct angle of needle entry was smaller at the 4th ICS in all age groups on both sides of the thorax. Incorrect angle of needle entry however is accompanied by a higher risk of injury at 2nd ICS. Furthermore, in some children aged 0 and 5 years, the heart or the thymus gland were found directly adjacent to the thoracic wall at 2nd ICS midclavicular line. Especially in small children risk of iatrogenic injury to vital structures by needle decompression is considerably high. The 4th ICS AAL offers a smaller chest wall thickness, but the width of the ICS is smaller and the risk of injury to the intercostal vessels and nerve is greater. Deviations from correct angle of entry however are accompanied by higher risk of injury to intrathoracic structures at the 2nd ICS. Furthermore, we found the heart and the thymus gland to be directly adjacent to the thoracic wall at the 2nd ICS MCL in a few children. From our point of view this puncture site can therefore not be recommended for decompression in small children. We therefore recommend 4th ICS AAL as the primary site of choice.

19 October 2015 in Pediatric Radiology
Verified
Journal Article
Closed access
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MWMeike Weis
Meike Weis
CHClaudia Hagelstein
Claudia Hagelstein
TDTheo Diehm
Theo Diehm
SSStefan O. Schoenberg
Stefan O. Schoenberg
KNK. Wolfgang Neff
K. Wolfgang Neff

1 June 2016 in American Journal of Roentgenology
Verified
Journal Article
Closed access
MWMeike Weis
Meike Weis
FZFrank G. Zoellner
Frank G. Zoellner
CHClaudia Hagelstein
Claudia Hagelstein
SSStefan O. Schoenberg
Stefan O. Schoenberg
KZKatrin Zahn
Katrin Zahn
KNK. Wolfgang Neff
K. Wolfgang Neff
OBJECTIVE. In severe cases of congenital diaphragmatic hernia (CDH), extracorporeal membrane oxygenation (ECMO) therapy improves survival. Later on, lung morbidity mainly defines development. The purpose of this study was to investigate whether 2-year-old children who need ECMO therapy after delivery have reduced perfusion MRI values as a sign of more severe lung hypoplasia than do children who do not need ECMO. MATERIALS AND METHODS. After CDH repair, 38 children underwent dynamic contrast-enhanced MRI with a 3D time-resolved angiography with stochastic trajectories sequence. Fifteen (39%) of the children had received ECMO therapy in the neonatal period. Pulmonary blood flow (PBF), pulmonary blood volume (PBV), and mean transit time were calculated for both lungs. In addition, the ratio of ipsilateral to contralateral lung was calculated for all parameters. RESULTS. In all children, those with and those without ECMO requirement, PBF and PBV were significantly reduced on the ipsilateral side (p < 0.05). C...