Data sharing presents several challenges to the informed consent process. Unique challenges emerge when sharing pediatric or pregnancy-related data. Here, parent preferences for sharing non-biological data are examined. Groups (n = 4 groups, 18 participants) and individual interviews (n = 19 participants) were conducted with participants from two provincial, longitudinal pregnancy cohorts (AOB and APrON). Qualitative content analysis was applied to transcripts of semi-structured interviews. Participants were supportive of a broad, one-time consent model or a tiered consent model. These preferences were grounded in the perceived obligations for reciprocity and accuracy. Parents want reciprocity among participants, repositories and researchers regarding respect and trust. Furthermore, parents’ worry about the interrelationships between the validity of the consent processes and secondary data use. Though parent participants agree that their research data should be made available for secondary use, they believe their consent is still required. Given their understanding that obtaining and informed consent can be challenging in the case of secondary use, parents agreed that a broad, one-time consent model was acceptable, reducing the logistical burden while maintaining respect for their contribution. This broad model also maintained participant trust in the research and secondary use of their data. The broad, one-time model also reflected parents’ perspectives surrounding child involvement in the consent process. The majority of parents felt decision made during childhood were the parents responsibility and should remain in parental purview until the child reaches the age of majority.

Journal of Medical Internet Research - International Scientific Journal for Medical Research, Information and Communication on the Internet #Preprint #PeerReviewMe: Warning: This is a unreviewed preprint. Readers are warned that the document has not been peer-reviewed by expert/patient reviewers or an academic editor, may contain misleading claims, and is likely to undergo changes before final publication, if accepted, or may have been rejected/withdrawn. Readers with interest and expertise are encouraged to sign up as peer-reviewer, if the paper is within an open peer-review period. Please cite this preprint only for review purposes or for grant applications and CVs (if you are the author). Background: Facebook, a popular social media site, allows users to communicate and exchange information. Social media sites can also be used as databases to search for individuals, including cohort participants. Retaining and tracking cohort participants is essential for the validity and generalizability of data in longitudinal research. Despite numerous strategies to minimize loss to follow-up, maintaining contact with participants is time consuming and resource intensive. Social media may provide alternative methods of contacting participants who consented to follow-up, but could not be reached, thus are potentially ‘lost to follow-up’. Objective: The aim of this study was to determine if Facebook was a feasible method for identifying and contacting participants of a longitudinal pregnancy cohort who were lost to follow-up, and re-engaging them without selection bias. Methods: This study used data from the All Our Families cohort. Of the 2827 mother-child dyads within the cohort, 237 participants were lost to follow-up. Participants were considered lost to follow-up if they had agreed to participate in additional research, completed at least one of the perinatal questionnaires, did not complete the 5-year postpartum questionnaire, and could not be contacted after numerous attempts via phone, email or mail. Participants were considered to be matched to a Facebook profile if two or more characteristics matched information previously collected. Participants were sent both a friend request and a personal message through the study’s Facebook page, and were invited to verify their enrollment in the study. The authors deemed a friend request was necessary due to the reduced functionality of non-friend direct messaging at the time. If the participant accepted the study’s friend request, then a personalized message was sent. Participants were considered re-connected if they accepted the friend request or responded to any messages. Participants were considered re-engaged if they provided up-to-date contact information. Results: Compared to the overall cohort, participants who were lost-to-follow-up (n=237) were younger (P = .003), non-married (P = .023), had lower household income (P < .001), less education (P < .001) and self-identified as being part of an ethnic minority (P = .015). Of the 237 participants considered lost to follow-up, 113 (47.7%) participants were identified using Facebook. Among the 113 identified participants, 87 were contacted (77.0%), 37 were re-connected (32.7%) and 20 were re-engaged (17.7%). No significant differences were found between those identified on Facebook (n=113) and those who were not able to be identified (n=124). Conclusions: Facebook identified 48% (113/237) of participants who were considered lost to follow-up and may be a practical tool for reconnecting with participants. The results from this study demonstrate that social networking sites, such as Facebook could be included in the development of retention practices, and can be implemented at any point in cohort follow-up.

Purpose: Despite the advances of modern operating rooms, surgeons often experience work environments that rival those of industrial workers with regard to the risk of musculoskeletal (MSK) injuries or disorders. Such injuries may result in loss of hours, decreased surgical volume, or premature retirement. This study aimed to investigate the prevalence and impact of MSK injuries among Canadian plastic surgeons and trainees. Methods: A cross-sectional, online survey was disseminated among Canadian plastic surgeons, defined as those registered as members of the Canadian Society of Plastic Surgeons, the Royal College of Physicians and Surgeons of Canada, or Plastic Surgery Residents. Results: This survey was disseminated to 604 Canadian plastic surgeons, fellows, and residents, of whom 139 responded (response rate 23.0%). Of the responders, 49.6% were male, 23.0% were >35 years of age, and 46.1% had been in practice for >10 years. The majority (72.7%) of respondents endorsed experiencing MSK symptoms after operating. Moreover, 18.7% of respondents felt their MSK symptoms had direct consequences on their performance as a surgeon. When MSK symptoms were reported to department heads, system change was only seen 44.4% of the time. Unsurprisingly, neck (76.2%), back (72.2%), and shoulders (48.5%) were the areas of pain most reported. Exercise was not shown to significantly reduce the impact of MSK symptoms resulting from operating ( P = .06). Conclusions: Musculoskeletal symptoms are common among plastic surgeons and directly impact the performance of a large proportion of surgeons. Besides traditional efforts to reinforce good posture while operating, best practice policies and operating room optimization with regard to ergonomics are warranted.

Background: Topical tranexamic acid (TXA), often combined with epinephrine, is used to reduce perioperative bleeding. This systematic review evaluates the safety and effectiveness of this combination across surgical procedures. Methods: A comprehensive search of eight databases was conducted from inception to 26 June 2025. Studies were eligible if they compared topically or locally applied TXA with epinephrine to epinephrine alone in surgical patients. Animal studies, case reports, non-English publications, and studies without comparators were excluded. Screening, data extraction, and risk of bias assessments followed PRISMA guidelines. Results: Ten studies met inclusion criteria (four randomized and six non-randomized), covering burn surgery, rhytidectomy, liposuction, septoplasty, endoscopic sinus surgery, dacryocystorhinostomy, and joint arthroplasty. TXA was applied topically or via tumescent infiltration. Most studies reported reduced intraoperative blood loss, improved surgical field visibility, lower drain output, shorter hemostasis time, and reduced transfusion rates. No increase in thromboembolic or major complications was observed. Conclusion: The combination of TXA and epinephrine appears safe and maybe effective for perioperative bleeding control. However, heterogeneity in dosing and outcomes limits generalizability. Further research is needed to standardize protocols and confirm long-term safety.

Acute coronary thrombosis is a known, but rare, contributor to morbidity and mortality in patients with thermal and electrical injuries. The overall incidence of myocardial infarction among burn patients is 1%, with an in-hospital post-infarction mortality of approximately 67%, whereas the overall mortality rate of the general burn patient population is from 1.4% to 18%. As such, early detection and effective peri-operative management are essential to optimize patient outcomes. Here, we report the details of the management of an adult male patient with a 65% total body surface area severe thermal injury, who developed an ST-elevation myocardial infarction (STEMI) in the resuscitation period. The patient was found to have 100% occlusion of his left anterior descending coronary artery, for which prompt coronary artery stent placement with a drug-eluting stent (DES) was performed. Following stent placement, the patient required dual antiplatelet therapy. The ongoing dual antiplatelet therapy required the development of a detailed peri-operative protocol involving pooled platelets, packed red blood cells, desmopressin (DDAVP™) and intraoperative monitoring of the patient’s coagulation parameters with thromboelastography for three staged operative interventions to achieve complete debridement and skin grafting of his burn wounds.

BACKGROUND Facebook, a popular social media site, allows users to communicate and exchange information. Social media sites can also be used as databases to search for individuals, including cohort participants. Retaining and tracking cohort participants are essential for the validity and generalizability of data in longitudinal research. Despite numerous strategies to minimize loss to follow-up, maintaining contact with participants is time-consuming and resource-intensive. Social media may provide alternative methods of contacting participants who consented to follow-up but could not be reached, and thus are potentially “lost to follow-up.” OBJECTIVE The aim of this study was to determine if Facebook was a feasible method for identifying and contacting participants of a longitudinal pregnancy cohort who were lost to follow-up and re-engaging them without selection bias. METHODS This study used data from the All Our Families cohort. Of the 2827 mother-child dyads within the cohort, 237 participants were lost to follow-up. Participants were considered lost to follow-up if they had agreed to participate in additional research, completed at least one of the perinatal questionnaires, did not complete the 5-year postpartum questionnaire, and could not be contacted after numerous attempts via phone, email, or mail. Participants were considered to be matched to a Facebook profile if 2 or more characteristics matched information previously collected. Participants were sent both a friend request and a personal message through the study’s Facebook page and were invited to verify their enrollment in the study. The authors deemed a friend request was necessary because of the reduced functionality of nonfriend direct messaging at the time. If the participant accepted the study’s friend request, then a personalized message was sent. Participants were considered reconnected if they accepted the friend request or responded to any messages. Participants were considered re-engaged if they provided up-to-date contact information. RESULTS Compared with the overall cohort, participants who were lost to follow-up (n=237) were younger (P=.003), nonmarried (P=.02), had lower household income (P<.001), less education (P<.001), and self-identified as being part of an ethnic minority (P=.02). Of the 237 participants considered lost to follow-up, 47.7% (113/237) participants were identified using Facebook. Among the 113 identified participants, 77.0% (87/113) were contacted, 32.7% (37/113) were reconnected, and 17.7% (20/113) were re-engaged. No significant differences were found between those identified on Facebook (n=113) and those who were not able to be identified (n=124). CONCLUSIONS Facebook identified 47.6% (113/237) of participants who were considered lost to follow-up, and the social media site may be a practical tool for reconnecting with participants. The results from this study demonstrate that social networking sites, such as Facebook, could be included in the development of retention practices and can be implemented at any point in cohort follow-up.