A new compact UWB multiple-input–multiple-output (MIMO) antenna is presented in this paper. The proposed antenna, with a compact size of 30 × 20 × 1.6 mm³, consists of a two-element microstrip line-fed pentagonal-shaped patch associated with a parasitic element and a partial ground plane. Three complementary split-ring resonator (CSRR) structures are integrated into the defected ground with the aims of reducing the mutual coupling and enhancing the bandwidth. A UWB impedance bandwidth is achieved covering the FCC band (3.1–10.6 GHz), corresponding to a reflection coefficient below −10 dB and a reduced mutual coupling below −22 dB. Additionally, acceptable limits of the diversity performance parameters are obtained. Furthermore, all the simulated outcomes of the suggested antenna are convenient for UWB-MIMO wireless applications. Measures carried out on the fabricated prototype of the antenna demonstrate good agreement between both the simulation and measurement results of the optimized two-port MIMO antenna.