Sigrid Grulke

Dr. Sigrid Grulke

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Research Focus & Metrics

Academic Career Length

25Years (2002-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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17 July 2022 in Veterinary Sciences
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Journal Article
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DVDenis Verwilghen
Denis Verwilghen
JEJack Easley
Jack Easley
TZTimo Zwick
Timo Zwick
MUMaggy Uhlhorn
Maggy Uhlhorn
SGSigrid Grulke
Sigrid Grulke
ABAstrid Bienert-Zeit
Astrid Bienert-Zeit
Suture exostosis is an intriguing and not uncommon pathology that has to be included in the differential diagnosis for horses with swelling of the head. Although several singular case reports have been published, no large case series is available. The aim of this study is to report a multicentric retrospective collection of suture exostosis cases. Data concerning horses with suture exostosis in the facial region were collected retrospectively. Information regarding breed, age, gender, history, imaging findings, initiated treatment, response to treatment and follow up was recorded. One hundred and five cases of various breeds were reported. Analysis revealed the cases could be grouped into four entities: 45 developed following sino-nasal surgery, 23 following trauma, seven with underlying sinus pathology and 25 idiopathic. Treatment consisted of sequestra removal, plate fixation, antimicrobial and anti-inflammatory drugs or no treatment. Whereas initial localized pain fades within few days or weeks, resolution or reduction of the swelling was obtained in most cases after 3 months to 1.5 years. The etiopathogenesis of suture exostosis seems to consist of different entities. Identification of an underlying cause, particularly the presence of a bone sequester and infection is important to speed up resolution and before concluding an idiopathic case. When performing sinusotomies, it is important to provide as little trauma as possible to the surgical site in order to prevent suture exostosis as a complication.


15 May 2020 in Veterinary Record
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SGSigrid Grulke
Sigrid Grulke
ASAlexandra Salciccia
Alexandra Salciccia
JRJosé Manuel Arévalo Rodríguez
José Manuel Arévalo Rodríguez
CSCharlotte Sandersen
Charlotte Sandersen
ICIsabelle Caudron
Isabelle Caudron
GPGeoffroy de la Rebière de Pouyade
Geoffroy de la Rebière de Pouyade
Background Epiploic foramen entrapment (EFE) of small intestine is a severe cause of strangulating small intestinal obstruction (SSI) with long-term survival seeming lower than for other causes of SSI in horses. Different techniques via laparoscopy or laparotomy for epiploic foramen (EF) closure have been developed. Methods This study describes a technique of peroperative mesh closure of the EF in clinical cases and their long-term follow up. Results In the study period of 5.5 years, 36 horses were admitted to the clinic with EFE. Of these, 17 horses had peroperative mesh closure, with resection anastomosis in 4 cases and enterotomy in 4 other cases. Fifteen of these survived to discharge. Long-term follow-up (one to three years, median three years) was favourable in all 15 horses not showing recurrence of EFE nor other related signs of colic. Laparoscopic evaluation of the EF was performed in two cases and showed integration of the mesh. One horse was euthanased 3.5 years after mesh placement for an unrelated cause and the mesh was well adherent obliterating the EF. Conclusion Mesh closure of EF during emergency coeliotomy did not cause short-term complications even in horses with resection or enterotomy and may reduce the risk of recurrence of EFE in horses.

11 March 2025 in Veterinary Sciences
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BDBienvenida Román Durá
Bienvenida Román Durá
ODOliver Dunham
Oliver Dunham
SGSigrid Grulke
Sigrid Grulke
ASAlexandra Salciccia
Alexandra Salciccia
JDJulien Dupont
Julien Dupont
charlotte sandersencharlotte sandersen
charlotte sandersen
Equine anesthesia is related to high morbidity and mortality rates and recent studies suggested that the period of recovery remains the phase associated with the greatest risk of mortality in horses. Intraoperative hypotension, hypoxemia, and hypercapnia are recognized as potential determinants of recovery quality. This study, conducted at the Equine University Hospital of Liege, aimed to explore how these factors influence recovery outcomes and compare complications between non-emergency and emergency procedures. We analyzed data from 1057 horses, with a mean weight of 498 kg (ranging from 150 to 850 kg) and a mean age of 10.7 (ranging from 0.5 to 37 years), undergoing standardized general anesthesia for non-emergency and emergency procedures to assess which factors influence recovery quality. Recoveries were graded as ‘good’ or ‘bad’ and age, sex, breed, American Society of Anesthesiologists (ASA) physical status classification, weight, anesthesia duration, presence of hypotension, hypoxemia, and hypercapnia were compared with a logistic regression analysis. Our findings highlight the multifactorial nature of anesthetic recovery in horses, with breed, age, anesthesia and recovery duration, and emergency status emerging as significant influencing factors. Additionally, monitoring and managing hypoxemia and hypotension remain critical due to their recognized impact on recovery quality. However, despite their clinical relevance, the specific effects of these variables on anesthetic recovery in horses remain insufficiently studied, emphasizing the need for further research to refine perioperative management strategies and improve outcomes.

22 June 2022 in Veterinary Sciences
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HCHélène CASALTA
Hélène CASALTA
VBValeria Busoni
Valeria Busoni
Justine EppeJustine Eppe
Justine Eppe
SGSigrid Grulke
Sigrid Grulke
AMAnne-Christine Merveille
Anne-Christine Merveille
KGKris Gommeren
Kris Gommeren
Ultrasonographic measurements of the caudal vena cava (CVC) and aorta (Ao) are known as reliable tools to assess intravascular volume status in humans. The aim of this study was to evaluate the feasibility of obtaining ultrasonographical measurements of CVC and Ao in two different views, assess intra- and interobserver variability, and study the effect of sex, age, body weight, and breed on measurements in healthy calves. The diameter and area of CVC and Ao were measured by a single investigator in two anatomic sites (subxiphoid and paralumbar window) in 48 calves aged less than 60 days and then repeated 2.5 months after the first assessment. For intra- and interobserver variability assessment, CVC and Ao measurements were repeated by three observers on five randomly selected calves. CVC and Ao measurements were easily obtained in PV and more difficult to obtain in SV. CVC and Ao area in PV showed high repeatability and reproducibility. A positive correlation was highlighted between age and CVC and Ao measurements in both sites. In conclusion, CVC size assessment by point of care ultrasound can be easily performed at a paralumbar site in calves under 4 months of age and could be used to assess intravascular volume status.

1 January 2008
Verified
Journal Article
Closed access
SGSigrid Grulke
Sigrid Grulke
TFThierry Franck
Thierry Franck
MGMonika Gangl
Monika Gangl
FPFabrice Péters
Fabrice Péters
ASAlexandra Salciccia
Alexandra Salciccia
DSDidier Serteyn
Didier Serteyn