SEBASTIANO FRANCHELLA

Dr. SEBASTIANO FRANCHELLA

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Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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14 December 2020 in Audiology and Neurotology
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Daniele BorsettoDaniele Borsetto
Daniele Borsetto
VCVirginia Corazzi
Virginia Corazzi
SFSEBASTIANO FRANCHELLA
SEBASTIANO FRANCHELLA
CBChiara Bianchini
Chiara Bianchini
SPStefano Pelucchi
Stefano Pelucchi
ACAndrea Ciorba
Andrea Ciorba
Aim: To assess the current opinion on the effects of hearing loss treatment by hearing aids (HAs) and the benefits of HA use on imbalance. Methods: PRISMA-compliant systematic review was done, including observational studies in patients affected by mild to severe sensorineural hearing loss with HAs, investigating the benefits of HAs on balance. Electronic searches were performed through Medline, Cochrane, Embase, Web of Science, and Scopus. Results: A total of 200 patients in 8 studies were included in this systematic review. Four studies were cross-sectional, 3 cross-sectional controlled and 1 prospective nonrandomized study. Static and dynamic balance in the aided condition improved in patients assessed using clinical investigations including Romberg test and Functional Ambulation Performance/mini-BESTest, respectively. Variable outcomes were found measuring static and dynamic balance during the aided condition with objective tests (computerized posturography, Mobility Lab device). Improved quality of life outcomes and self-confidence were noted, while subjective measurements of balance had conflicting results. Conclusion: Although an improvement in balance in patients with HAs has been shown in certain conditions, the overall benefit is still unclear and it is only possible to speculate that HAs may also improve static, dynamic, or subjective perception of balance function in adults affected by hearing loss.

28 February 2023 in Audiology Research
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Journal Article
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SFSEBASTIANO FRANCHELLA
SEBASTIANO FRANCHELLA
MAMarzia Ariano
Marzia Ariano
FBFrancesca Bevilacqua
Francesca Bevilacqua
SCStefano Concheri
Stefano Concheri
Elisabetta ZanolettiElisabetta Zanoletti
Elisabetta Zanoletti
Intralabyrinthine schwannomas (ILS) are rare benign tumours arising from the peripheral branches of the cochlear or vestibular nerves in the membranous labyrinth, intracochlear schwannomas being the most frequent ones. When hearing is no longer feasible on the affected side, surgical removal along with simultaneous cochlear implantation can be proposed to the patient. We hereby present a systematic review of the literature on the topic, as well as two original cases from our centre (Ospedale Università degli Studi di Padova). Cochlear implantation in intracochlear schwannomas is feasible, with overall satisfactory hearing outcomes in accordance with the evidence found in the literature.

1 June 2018 in International Journal of Pediatric Otorhinolaryngology
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Journal Article
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SFSEBASTIANO FRANCHELLA
SEBASTIANO FRANCHELLA
RBRoberto Bovo
Roberto Bovo
LBLuigia Bandolin
Luigia Bandolin
FGFlavia Gheller
Flavia Gheller
SMSilvia Montino
Silvia Montino
Alessandro MartiniAlessandro Martini
Alessandro Martini

15 December 2022 in Audiology Research
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MAMarzia Ariano
Marzia Ariano
SFSEBASTIANO FRANCHELLA
SEBASTIANO FRANCHELLA
GTGiulia Tealdo
Giulia Tealdo
Elisabetta ZanolettiElisabetta Zanoletti
Elisabetta Zanoletti
With the recent scientific and technical developments, hearing preservation surgery is becoming a growing objective in inner ear pathologies, especially for vestibular schwannomas. In this review, we aim to describe the pros and cons of the following cochlear nerve monitoring techniques: ABRs (auditory brainstem responses), DENM (direct eighth cranial nerve monitoring), EcochG (electrocochleography), CNAP (cochlear compound nerve action potentials), DPOAE (distortion product otoacoustic emissions), PAMRs (postauricular muscle responses). The Cochrane library, Scopus, DynaMed, and PubMed databases were screened to obtain any relevant papers from October 2009 to the present day. Due to the heterogeneity of the existing studies in the literature, there is no way to tell whether a technique is better than another. All authors reported satisfactory outcomes with the cochlear nerve monitoring techniques tested, either alone or in combination.

1 July 2016 in Reports of Practical Oncology and Radiotherapy
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Journal Article
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EZElisabetta Zanoletti
Elisabetta Zanoletti
GMGino Marioni
Gino Marioni
SFSEBASTIANO FRANCHELLA
SEBASTIANO FRANCHELLA
SMSara Munari
Sara Munari
RPRoberto Pareschi
Roberto Pareschi
Alessandro MartiniAlessandro Martini
Alessandro Martini
Prognostic factors, rational management, and the ongoing investigations regarding temporal bone squamous cell carcinoma (TBSCC) have been critically reviewed. TBSCC is an uncommon, aggressive malignancy. Although some progress has been made in treating this aggressive tumor, the prognosis in advanced cases remains poor. A systematic search of the literature for articles published between 2009 and October 2014 was performed using the PubMed (http://www.pubmed.gov) electronic database. Given the particular anatomical site of TBSCC, its prognosis is significantly influenced by any direct involvement of nearby structures. The extent of the primary tumor is generally considered one of the most important prognostic factors and it is frequently related to prognosis even more strongly than N stage. For TBSCC, biomarker investigations in surgical specimens are only just beginning to appear in the oncological literature. Given the particular features of TBSCC, the sub-specialty of otologic oncology seems to be emerging as a defined area of practice involving multidisciplinary team comprising oto-neurosurgeons, head and neck surgeons, plastic surgeons, oncologists, radiotherapists, dedicated radiologists, and pathologists.

22 February 2024 in Audiology Research
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Journal Article
Open access
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SCStefano Concheri
Stefano Concheri
DBDavide Brotto
Davide Brotto
MAMarzia Ariano
Marzia Ariano
Antonio DaloisoAntonio Daloiso
Antonio Daloiso
Valerio Maria Di Pasquale FiascaValerio Maria Di Pasquale Fiasca
Valerio Maria Di Pasquale Fiasca
SFSEBASTIANO FRANCHELLA
SEBASTIANO FRANCHELLA
Objectives: The objectives were to present the real-time estimated values of cochlear implant (CI) electrode insertion speed (IS) during intraoperative sessions using the Cochlear Nucleus SmartNav System to assess whether this measure affected CI outcomes and to determine whether real-time feedback assists expert surgeons in achieving slow insertion. Methods: The IS was measured in 52 consecutive patients (65 implanted ears) using the CI632 electrode. The IS values were analyzed in relation to procedure repetition over time, NRT ratio, and CI audiological outcomes. Results: The average IS was 0.64 mm/s (SD = 0.24); minimum and maximum values were 0.23 and 1.24 mm/s, respectively. The IS significantly decreased with each array insertion by the operator (p = 0.006), and the mean decreased by 24% between the first and last third of procedures; however, this reduction fell within the error range of SmartNav for IS (+/−0.48 mm/s). No correlation was found between IS and the NRT ratio (p = 0.51), pure-tone audiometry (PTA) at CI activation (p = 0.506), and PTA (p = 0.94) or word recognition score (p = 0.231) at last evaluation. Conclusions: The estimated IS reported by SmartNav did not result in a clinically significant reduction in insertion speed or an improvement in CI hearing outcomes. Real-time feedback of IS could potentially be used for training, but its effectiveness requires confirmation through additional studies and more accurate tools. Implementation of IS assessment in clinical practice will enable comparisons between measurement techniques and between manual and robot-assisted insertions. This will help define the optimal IS range to achieve better cochlear implant (CI) outcomes.