Plant communities in urban wetland parks (UWP) have significant eco-healthcare benefits in terms of regulating the climate and improving the human living environment. However, factors influencing the regulation of eco-healthcare benefits are unclear. Taking Huaxi Ten Mile Beach National Urban Wetland Park as an example, the urban wetland park comprehensive healthcare index (UPCHI) was constructed based on an outdoor survey and indoor analysis to evaluate the UWP’s eco-healthcare benefits. Pathway analysis was used to investigate how climatic, geographic, and plant factors interact to affect the UPCHI. The results show that, over the whole year, tree–shrub–herb showed the best performance in terms of reducing PM_2.5, PM₁₀, and noise, as well as raising negative air ion concentrations; however, human comfort performed the worst. The UPCHI was generally beyond level Ⅲ (0.49–0.58) in the spring and summer, indicating that there are eco-healthcare benefits. Overall, the deciduous tree–shrub–herb community had the highest annual mean UPCHI, and more than half of the plant communities’ eco-healthcare benefits were class Ⅱ, which is very beneficial for eco-healthcare. The main direct factors on UPCHI were illumination intensity (0.68) and tree height (0.90), while canopy height (0.64–0.59) and tree crown radius/canopy height (0.72–0.14) directly or indirectly influenced UPCHI. The distance from the edge of the mountain (−0.39–−0.322) had a direct negative, but minor, effect on UPCHI. This study will assist residents with selecting suitable times and places for wetland recreation and healthcare activities, and it offers a valuable reference for the future planning and design of UWP plant communities.