Leonard Ignat

Dr. Leonard Ignat


Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 May 2023 in Textiles
Verified
Journal Article
Open access
PDF file
FTFulga Tanasa
Fulga Tanasa
CTCarmen-Alice Teacă
Carmen-Alice Teacă
MNMarioara Nechifor
Marioara Nechifor
MIMaurusa Ignat
Maurusa Ignat
Ioana A. DuceacIoana A. Duceac
Ioana A. Duceac
LILeonard Ignat
Leonard Ignat
Textiles with antimicrobial functionality have been intensively and extensively investigated in the recent decades, mostly because they are present in everyday life in various applications: medicine and healthcare, sportswear, clothing and footwear, furniture and upholstery, air and water purification systems, food packaging etc. Their ability to kill or limit the growth of the microbial population in a certain context defines their activity against bacteria, fungi, and viruses, and even against the initial formation of the biofilm prior to microorganisms’ proliferation. Various classes of antimicrobials have been employed for these highly specialized textiles, namely, organic synthetic reagents and polymers, metals and metal oxides (micro- and nanoparticles), and natural and naturally derived compounds, and their activity and range of applications are critically assessed. At the same time, different modern processing techniques are reviewed in relation to their applications. This paper focuses on some advances and challenges in the field of antimicrobial textiles given their practical importance as it appears from the most recent reports in the literature.

25 December 2023 in Polymers
Verified
Journal Article
Open access
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Cristian-Dragos VarganiciCristian-Dragos Varganici
Cristian-Dragos Varganici
Liliana RosuLiliana Rosu
Liliana Rosu
Dan RosuDan Rosu
Dan Rosu
IRIrina Rosca
Irina Rosca
MIMaurusa-Elena Ignat
Maurusa-Elena Ignat
LILeonard Ignat
Leonard Ignat
In this study, the effects of three diamine curing agents (aromatic, cycloaliphatic, aliphatic) on the photochemical behavior of bisphenol A diglycidyl ether networks were comparatively examined. In order to monitor structural changes and study the curing agents’ action mode, the cured epoxy resins were characterized before and after photoirradiation by means of Fourier-transform infrared spectroscopy, contact angle, differential scanning calorimetry, scanning electron microscopy, and energy-dispersive X-ray analysis, mass loss, and color modification measurements. Water absorption tests were also conducted. The cured epoxy resins are to be used in different multicomponent polymer materials for outdoor protection. The presence of the cycloaliphatic hardener led to reduced water absorption, and after UV irradiation, an increase in the glass transition temperature and lowest mass loss of the corresponding cured epoxy resin compared to the ones cured with aromatic and aliphatic hardener.

1 September 2013 in Fibers and Polymers
Verified
Journal Article
Closed access
PDF file
MÎMîndru
Mîndru
TBTudorel Bălău
Tudorel Bălău
LILeonard Ignat
Leonard Ignat
IBIulia Bălău
Iulia Bălău
Mariana PintealaMariana Pinteala
Mariana Pinteala

9 February 2024 in Heliyon
Verified
Journal Article
Open access
IMIoana Cristina Marinas
Ioana Cristina Marinas
LILeonard Ignat
Leonard Ignat
IMIgnat E. MaurușA
Ignat E. MaurușA
MGMadalina D. Gaboreanu
Madalina D. Gaboreanu
CACoroabă Adina
Coroabă Adina
Mariana PintealaMariana Pinteala
Mariana Pinteala
Chronic wounds represent one of the complications that might occur from the disruption of wound healing process. Recently, there has been a rise in interest in employing nanotechnology to develop novel strategies for accelerating wound healing. The aim of the present study was to use a green synthesis method to obtain AgNPs/NaLS systems useful for wounds management and perform an in-depth investigation of their behavior during and post-synthesis as well as of their biological properties. The colloids obtained from silver nanoparticles (AgNPs) and commercial sodium lignosulfonate (NaLS) in a single-pot aqueous procedure have been fully characterized by UV-Vis, FT-IR, DLS, TEM, XRD, and XPS to evaluate the synthesis efficiency and to provide new insights in the process of AgNPs formation and NaLS behavior in aqueous solutions. The effects of various concentrations of NaLS (0-16 mg/mL) and AgNO3 (0-20 mM) and of two different temperatures on AgNPs formation have been analyzed. Although the room temperature is feasible for AgNPs synthesis, the short mixing at 70 °C significantly increases the speed of nanoparticle formation and storage stability. In all experimental conditions AgNPs of 20-40 nm in size have been obtained. The antimicrobial activity assessed quantitatively on clinical and reference bacterial strains, both in suspension and biofilm growth state, revealed a broad antimicrobial spectrum, the most intensive inhibitory effect being noticed against Pseudomonas aeruginosa and Escherichia coli strains. The AgNP/NaLS enhanced the NO extracellular release, potentially contributing to the microbicidal and anti-adherence activity by protein oxidation. Both AgNP/NaLS and NaLS were non-hemolytic (hemolytic index<5%, 2.26 ± 0.13% hemolysis) and biocompatible (102.17 ± 3.43 % HaCaT cells viability). The presence of AgNPs increased the antioxidative activity and induced a significant cytotoxicity on non-melanoma skin cancer cells (62.86 ± 8.27% Cal-27 cells viability). Taken together, all these features suggest the multivalent potential of these colloids for the development of novel strategies for wound management, acting by preventing infection-associated complications and supporting the tissue regeneration.

7 April 2022 in ChemistrySelect
Verified
Journal Article
Closed access
MIMaurusa‐Elena Ignat
Maurusa‐Elena Ignat
VDViorica Dulman
Viorica Dulman
LILeonard Ignat
Leonard Ignat
MIMaria Ignat
Maria Ignat
IHIonel Humelnicu
Ionel Humelnicu