Yaman Degirmenci

Dr. Yaman Degirmenci

orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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19 December 2022 in Journal of Obstetrics and Gynaecology Research
Verified
Journal Article
Open access
YDYaman Degirmenci
Yaman Degirmenci
MSMarkus Schepers
Markus Schepers
JSJoscha Steetskamp
Joscha Steetskamp
AHAnnette Hasenburg
Annette Hasenburg
CSChristine Skala
Christine Skala
Aim: The gold standard to treat an apical pelvic organ prolapse is the abdominal route via a sacrocolpopexy, which is also reproduced by laparoscopic route. A laparoscopic sacrocolpopexy however, requires surgical expertise. Three‐dimensional (3D) laparoscopy has been developed to overcome the lack of depth perception, that is a known disadvantage of conventional two‐dimensional (2D) laparoscopy. This procedure can accelerate the learning curve and optimize the intra‐, peri‐, and postoperative outcomes. This study aims to compare 3D laparoscopy to traditional 2D laparoscopy for sacrocolpopexy.Methods: Data from 132 patients who underwent a sacrocolpopexy with 2D or 3D laparoscopy in Department of Obstetrics and Gynecology, University Medical Center of the Johannes Gutenberg University, between June 2012 and September 2021, were collected retrospectively. Seventy‐one laparoscopic sacrocolpopexy operations in 2D (n = 23) and 3D (n = 48) group were reviewed and compared regarding the duration of surgery, blood loss and the length of hospital admission as primary objectives.Results: There were no differences in the baseline demographics between the two groups. The estimated blood loss (1.0 (±0.6) g/dL vs 1.7 (±1.0) g/dL, p = 0.010), and duration of surgery (115.4 (±34.7) min. vs 134.7 (±26.2) min., p = 0.012) was significantly better in favor of 3D laparoscopy. The length of hospital stay was comparable in both groups (p = 0.833). Furthermore, no differences were observed between the groups regarding other surgical outcomes.Conclusion: 3D laparoscopy shows a significant benefit in terms of estimated blood loss and surgery duration among complex urogynecological surgeries compared to traditional 2D laparoscopy.

8 February 2024 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
YDYaman Degirmenci
Yaman Degirmenci
KSKathrin Stewen
Kathrin Stewen
ADAnna Dionysopoulou
Anna Dionysopoulou
LSLina Judit Schiestl
Lina Judit Schiestl
KHKonstantin Hofmann
Konstantin Hofmann
RSRoxana Schwab
Roxana Schwab
Background: Pelvic organ prolapse constitutes a prevalent condition associated with a considerable impact on the quality of life. The utilization of transvaginal mesh surgery for managing POP has been a subject of extensive debate. Globally, trends in TVM surgery experienced significant shifts subsequent to warnings issued by the FDA. Methods: This study aims to explore temporal patterns in transvaginal mesh surgery in the German healthcare system. A comprehensive analysis was conducted on in-patient data from the German Federal Statistical Office spanning 2006 to 2021. A total of 1,150,811 operations, each associated with specific codes, were incorporated into the study. Linear regression analysis was employed to delineate discernible trends. Results: The trends in transvaginal mesh surgery within the anterior compartment exhibited relative stability (p = 0.147); however, a significant decline was noted in all other compartments (posterior: p < 0.001, enterocele surgery: p < 0.001). A subtle increasing trend was observed for uterine-preserving transvaginal mesh surgery (p = 0.045). Conclusion: Surgical trends over the specified timeframe demonstrate how POP management has evolved globally. Notably, despite observed fluctuations, transvaginal mesh surgery remains a viable option, particularly for specific cases with a high risk of relapse and contraindications to alternative surgical approaches.

22 March 2022 in Clinical Case Reports
Verified
Journal Article
Open access
YDYaman Degirmenci
Yaman Degirmenci
JSJoscha Steetskamp
Joscha Steetskamp
DMDoris Macchiella
Doris Macchiella
AHAnnbalou Hasenburg
Annbalou Hasenburg
AHAnnette Hasenburg
Annette Hasenburg
Vasa previa is a rare condition. However, since the increase in assisted reproductive technologies (ARTs), clinicians are more frequently confronted with this complication. In this study, we present five cases of vasa previa prenatally diagnosed from a tertiary referral hospital with approximately 2000 births yearly.

17 November 2025 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
YDYaman Degirmenci
Yaman Degirmenci
CSCeren Efe Sayın
Ceren Efe Sayın
ISIna Shehaj
Ina Shehaj
MSMona Wanda Schmidt
Mona Wanda Schmidt
GKGilbert Georg Klamminger
Gilbert Georg Klamminger
Background/Objectives: Pelvic organ prolapse (POP) surgery can lead to postoperative stress urinary incontinence (SUI) in previously continent women, termed de novo SUI. This study assessed the incidence and risk factors of de novo SUI after apical POP repair, hypothesizing that reduced bladder neck elasticity—particularly within the zone of critical elasticity (ZCE) described by the Integral Theory—contributes to its development. Methods: A retrospective single-center analysis was performed in 206 postmenopausal women (≥60 years) who underwent apical POP surgery without concomitant anti-incontinence procedures. Patients were classified by surgical approach as laparoscopic sacrocolpopexy (SCP) or vaginal native tissue repair. Results: The overall incidence of de novo SUI was 8.7%. Laparoscopic SCP for vaginal vault prolapse was significantly associated with a higher risk of postoperative SUI (OR 10.37, 95% CI 2.70–39.79, p = 0.001), whereas other procedures showed no significant association. Neither prior hysterectomy nor cystocele stage was an independent predictor of de novo SUI. Conclusions: These results suggest that surgical alteration of the ZCE—particularly excessive tension or reduced elasticity near the bladder neck—may impair urethral closure. Therefore, preserving ZCE integrity and carefully adjusting mesh tension during apical POP repair may reduce the risk of de novo SUI.

20 February 2025 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
YDYaman Degirmenci
Yaman Degirmenci
ISIna Shehaj
Ina Shehaj
MAMatthias Alexa
Matthias Alexa
GKGilbert Georg Klamminger
Gilbert Georg Klamminger
MSMona Wanda Schmidt
Mona Wanda Schmidt
RSRoxana Schwab
Roxana Schwab
Background/Objectives: Pelvic organ prolapse (POP) is a common condition that significantly affects quality of life. Obliterative surgery, such as colpocleisis, represents an alternative to reconstructive surgery with a historically established background. The trends in apical prolapse surgery have undergone substantial changes following FDA warnings. This study aims to analyze the trend of obliterative surgery within the context of apical POP surgery in the German healthcare system, considering global shifts, particularly following FDA warnings. Methods: A comprehensive analysis of in-patient data from the German Federal Statistical Office was carried out for the period between 2005 and 2021. The study included a total of 530,107 procedures, each classified by specific codes. Linear regression analysis was applied to identify and characterize trends in surgical patterns. Results: The trends in obliterative surgery showed a significant decline over the years (p < 0.001), particularly notable in older women. In contrast, a significant increasing trend was observed in the proportion of abdominal surgeries relative to the total number of procedures over time (p < 0.001), especially in the younger age group. Conclusions: Surgical trends over the specified timeframe highlight the notable evolution of POP management. Despite observed global fluctuations, obliterative surgery in Germany appeared to follow a declining trend in the changing mesh era, shaped by varying perspectives on the matter. The shifting global trend should be closely monitored and considered in urogynecological training.

21 November 2024 in Diagnostics
Verified
Journal Article
Open access
PDF file
YDYaman Degirmenci
Yaman Degirmenci
JSJoscha Steetskamp
Joscha Steetskamp
RSRoxana Schwab
Roxana Schwab
AHAnnette Hasenburg
Annette Hasenburg
Markus SchepersMarkus Schepers
Markus Schepers
CSChristine Skala
Christine Skala
Background/Objectives: Anal incontinence is linked to pelvic floor dysfunction. Diagnosis involves assessing both the function and structure of the anorectal unit. Although transperineal ultrasound has gained attention as a less invasive option, its effectiveness as a diagnostic tool for evaluating the relationship between structure and function is still debated. This study aimed to explore the relationship between quantitative measurements of anal sphincter and pelvic floor structures as well as the subjective symptoms and objective assessments of sphincter function regarding anal incontinence. Methods: 50 women with pelvic floor dysfunction were recruited for the study. The severity of anal incontinence was assessed using the CACP score. Ultrasound imaging was employed to measure anal sphincter area, while sphincter pressures were evaluated through manometry. The relationships between variables were analyzed using Pearson’s and Spearman’s correlation tests. Results: The mean anal sphincter area was 5.51 cm2 at rest and 4.06 cm2 during maximal contraction. Resting anal sphincter pressure had an average of 46.29 mmHg, and contraction pressure averaged 103.25 mmHg. No significant correlation was found between the anal sphincter area and pressure at rest (r = 0.018) or during contraction (r = −0.210). However, a moderate correlation was observed between the change in sphincter pressure and area during contraction (r = 0.312). The CACP score showed no significant correlation with the sphincter area at rest (r = −0.084) but was weakly correlated during contraction (r = −0.270). Conclusions: Conventional diagnostic tools for evaluating anal incontinence can be uncomfortable and are not always readily available. Perineal sonography presents a promising, less invasive alternative for dynamic assessment of the anal sphincter.