Drug discovery is a time-consuming, high-investment, and high-risk process in traditional drug development. Drug repositioning has become a popular strategy in recent years. Different from traditional drug development strategies, the strategy is efficient, economical and riskless. There are usually three kinds of approaches: computational approaches, biological experimental approaches, and mixed approaches, all of which are widely used in drug repositioning. In this paper, we reviewed computational approaches and highlighted their characteristics to provide references for researchers to develop more powerful approaches. At the same time, the important findings obtained using these approaches are listed. Furthermore, we summarized 76 important resources about drug repositioning. Finally, challenges and opportunities in drug repositioning are discussed from multiple perspectives, including technology, commercial models, patents and investment.

Nowadays stereo cameras are more commonly adopted in emerging devices such as dual-lens smartphones and unmanned aerial vehicles. However, they also suffer from blurry images in dynamic scenes which leads to visual discomfort and hampers further image processing. Previous works have succeeded in monocular deblurring, yet there are few studies on deblurring for stereoscopic images. By exploiting the two-view nature of stereo images, we propose a novel stereo image deblurring network with Depth Awareness and View Aggregation, named DAVANet. In our proposed network, 3D scene cues from the depth and varying information from two views are incorporated, which help to remove complex spatially-varying blur in dynamic scenes. Specifically, with our proposed fusion network, we integrate the bidirectional disparities estimation and deblurring into a unified framework. Moreover, we present a large-scale multi-scene dataset for stereo deblurring, containing 20,637 blurry-sharp stereo image pairs from 135 diverse sequences and their corresponding bidirectional disparities. The experimental results on our dataset demonstrate that DAVANet outperforms state-of-the-art methods in terms of accuracy, speed, and model size.