Clare C.W. Yu

Dr. Clare C.W. Yu

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Research Focus & Metrics

Academic Career Length

27Years (2000-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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27 February 2018 in BMC Psychiatry
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Journal Article
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CYClare C.W. Yu
Clare C.W. Yu
SWSimpson W. L. Wong
Simpson W. L. Wong
FLFarica S. F. Lo
Farica S. F. Lo
RSRaymond C. H. So
Raymond C. H. So
DCDorothy F. Y. Chan
Dorothy F. Y. Chan
Suboptimal physical activity levels and tolerance, poor motor skills and poor physical health are demonstrated in children with Autism Spectrum Disorder (ASD). We speculate that social interaction and communication deficits in children with ASD are two major factors that hinder these children from actively participating in group physical activities. While previous studies have demonstrated that exercise intervention improves motor skills and behavioral outcomes in children with ASD, these programs tend to focus only on a single sport, which may not cater to the interests of different children with ASD. In this protocol, a game-based exercise training program designed by a multi-disciplinary team (pediatrics, physical education and psychology) will be implemented by front-line healthcare providers trained following the train-the-trainer (TTT) model and subjected to validation. Using a randomized controlled trial design, the effectiveness of the game-based exercise program will be examined for 112 young children with ASD. These children were randomly assigned to two groups, which will be tested and trained in either one of the two arms of the waitlist conditions (control and intervention). The assessment of physical and psychological traits will be conducted at baseline (pre-test), at 16-weeks (post-treatment) and at 32-weeks (follow-up) of the program. Most of the interventions designed for ASD children target either their psychological traits or physical conditions, without bridging the two states. With the recognition of bidirectional relations between mental and physical health, the present game-based exercise program which includes multiple level of difficulties was developed to equip ASD children with the necessary skills for engaging in sustainable team sports or even professional sport training. The program, if effective, will provide an entertaining and engaging training for whole-person development among children with ASD. This study is registered with the Chinese Clinical Trial Registry ( ChiCTR-IOR-17011898 ). Registered 6th July 2017.

20 September 2021 in PLOS ONE
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TCTianhao Chen
Tianhao Chen
JLJingxia Lin
Jingxia Lin
YLYuzhe Lin
Yuzhe Lin
LXLin Xu
Lin Xu
DLDian Lu
Dian Lu
CYClare C.W. Yu
Clare C.W. Yu
Background: Obesity is a serious social and public health problem in the world, especially in children and adolescents. For school-age children with obesity, this stage is in the transition from childhood to adolescence, and both physical, psychological, and external environments will be full of challenges. Studies have showed that school-age children are the largest proportion of people who continue to be obese in adulthood. Physical exercise is considered as an effective way to control weight. Therefore, we focus on this point to study which factors will be improved to reduce childhood obesity. Objective: To assess the effects of aerobic and resistance exercise on physical indexes, such as body mass index (BMI) and body fat percentage, and cardiovascular risk factors such as VO2peak, triglycerides (TG) and low-density lipoprotein (LDL), high-density lipoprotein (HDL), total cholesterol (TC), insulin and insulin resistance in school-age children who are overweight or obese. Method: PubMed, SPORTDiscus, Medline, Cochrane-Library, Scopus, Ovid and Web of Science were searched to locate studies published between 2000 and 2021 in obese and overweight school-age children between 6–12 years old. The articles are all randomized controlled trials (RCTs) and in English. Data were synthesized using a random-effect or a fixed-effect model to analyze the effects of aerobic and resistance exercise on six elements in in school-age children with overweight or obese. The primary outcome measures were set for BMI. Results: A total of 13 RCTs (504 participants) were identified. Analysis of the between-group showed that aerobic and resistance exercise were effective in improving BMI (MD = -0.66; p < 0.00001), body fat percentage (MD = -1.29; p = 0.02), TG (std.MD = -1.14; p = 0.005), LDL (std.MD = -1.38; p = 0.003), TC (std.MD = -0.77; p = 0.002), VO2peak (std.MD = 1.25; p = 0.001). However, aerobic and resistance exercise were not significant in improving HDL (std.MD = 0.13; p = 0.27). Conclusions: Aerobic exercise and resistance exercise are associated with improvement in BMI, body fat percentage, VO2peak, TG, LDL, TC, while not in HDL in school-age children with obesity or overweight. Insulin and insulin resistance were not able to be analyzed in our review. However, there are only two articles related to resistance exercise in children with obesity and overweight at school age, which is far less than the number of 12 articles about aerobic exercise, so we cannot compare the effects of the two types of exercises.

1 October 2008 in Preventive Medicine
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Journal Article
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AMAlison M. McManus
Alison M. McManus
RMRich S.W. Masters
Rich S.W. Masters
RLRaija M.T. Laukkanen
Raija M.T. Laukkanen
CYClare C.W. Yu
Clare C.W. Yu
CSCindy H.P. Sit
Cindy H.P. Sit
FLFiona Ling
Fiona Ling

1 September 2015 in Safety and Health at Work
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Journal Article
Open access
CYClare C.W. Yu
Clare C.W. Yu
CAChun T. Au
Chun T. Au
FLFrank Y.F. Lee
Frank Y.F. Lee
RSRaymond C.H. So
Raymond C.H. So
JWJohn P.S. Wong
John P.S. Wong
AMAlison M. McManus
Alison M. McManus
Overweight, obesity, and cardiovascular disease risk factors are prevalent among firefighters in some developed countries. It is unclear whether physical activity and cardiopulmonary fitness reduce cardiovascular disease risk and the cardiovascular workload at work in firefighters. The present study investigated the relationship between leisure-time physical activity, cardiopulmonary fitness, cardiovascular disease risk factors, and cardiovascular workload at work in firefighters in Hong Kong. Male firefighters (n = 387) were randomly selected from serving firefighters in Hong Kong (n = 5,370) for the assessment of cardiovascular disease risk factors (obesity, hypertension, diabetes mellitus, dyslipidemia, smoking, known cardiovascular diseases). One-third (Target Group) were randomly selected for the assessment of off-duty leisure-time physical activity using the short version of the International Physical Activity Questionnaire. Maximal oxygen uptake was assessed, as well as cardiovascular workload using heart rate monitoring for each firefighter for four "normal" 24-hour working shifts and during real-situation simulated scenarios. Overall, 33.9% of the firefighters had at least two cardiovascular disease risk factors. In the Target Group, firefighters who had higher leisure-time physical activity had a lower resting heart rate and a lower average working heart rate, and spent a smaller proportion of time working at a moderate-intensity cardiovascular workload. Firefighters who had moderate aerobic fitness and high leisure-time physical activity had a lower peak working heart rate during the mountain rescue scenario compared with firefighters who had low leisure-time physical activities. Leisure-time physical activity conferred significant benefits during job tasks of moderate cardiovascular workload in firefighters in Hong Kong.

1 November 2007 in Medicine & Science in Sports & Exercise
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Journal Article
Closed access
ECEva Y. W. Chu
Eva Y. W. Chu
AMALISON M. McMANUS
ALISON M. McMANUS
CYClare C.W. Yu
Clare C.W. Yu
Sed experiment to calibrate the RT3 device across a range of intensities. Oxygen uptake during sedentary tasks and ambulation was aligned, with corresponding RT3 output, to one of four intensity categories (sedentary, < 2 METs; low, ≥ 2 but < 3 METs; moderate, ≥ 3 but < 6; and vigorous, ≥ 6). Threshold values were derived using receiver operator curves to distinguish the sedentary from low intensity, low from moderate intensity, and moderate from vigorous intensity. These were confirmed in an independent sample of 46 similarly aged children. Results: RT3 movement counts increased in a linear manner with scaled oxygen uptake from stationary to vigorous movement (r2 = 0.83). The ROC-derived thresholds showed a good ability to discriminate between nonambulatory and ambulatory tasks, as well as distinguish between low, moderate, and vigorous ambulation (sensitivity values of 87-100% and specificity values of 97-100%). ROC analyses in the independent sample showed sensitivity and specificity values ranging from 72 to 98%, indicating that the thresholds provided an accurate distinction between the four intensity categories. A Cohen's kappa of κ = 0.92 confirmed that the lower threshold had near-perfect agreement with the independent sample, whereas the moderate-intensity and vigorous-intensity thresholds showed good agreement with the independent sample (κ = 0.63 and 0.65, respectively). Conclusion: The RT3 accelerometer provides an acceptable marker of both sedentary and ambulatory behavior in Chinese children....

8 March 2019 in PLOS ONE
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KHKwong-Chung Hung
Kwong-Chung Hung
HCHo-Wa Chung
Ho-Wa Chung
CYClare C.W. Yu
Clare C.W. Yu
HLHong-Chung Lai
Hong-Chung Lai
Fenghua SunFenghua Sun
Fenghua Sun
The purpose of this study was to examine the effects of 8-week core training on core endurance and running economy in college athletes. Twenty-one male college athletes were randomly divided into 2 groups: a control group (CON) (n = 10) and a core training group (CT) (n = 11). Both groups maintained their regular training, whereas CT attended 3 extra core training sessions per week for 8 weeks. The participants were assessed before and after the training program using sensory organization test (SOT), sport-specific endurance plank test (SEPT) and 4-stage treadmill incremental running test (TIRT). Compared with the pre-test, significant improvements were observed in post-test SOT (78.8 ± 4.8 vs. 85.3 ± 4.8, p = 0.012) and SEPT (193.5 ± 71.9 s vs. 241.5 ± 98.9 s, p = 0.001) performances only in CT. In the TIRT, the post-test heart rate values were lower than the pre-test values in CT in the first 3 stages. In stage 4, the post-test oxygen consumption (VO2) was lower than that in pre-test in CT (VO2: 52.4 ± 3.5 vs. 50.0 ± 2.9 ml/kg/min, p = 0.019). These results reveal that 8-week core training may improve static balance, core endurance, and running economy in college athletes.