Recent advancements in cybersecurity threats and malware have brought into question the safety of modern software and computer systems. As a direct result of this, artificial intelligence-based solutions have been on the rise. The goal of this paper is to demonstrate the efficacy of memory-optimized machine learning solutions for the task of static analysis of software metadata. The study comprises an evaluation and comparison of the performance metrics of three popular machine learning solutions: artificial neural networks (ANN), support vector machines (SVMs), and gradient boosting machines (GBMs). The study provides insights into the effectiveness of memory-optimized machine learning solutions when detecting previously unseen malware. We found that ANNs shows the best performance with 93.44% accuracy classifying programs as either malware or legitimate even with extreme memory constraints.