Sharif Mohammed Sadat

Mr. Sharif Mohammed Sadat

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Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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2 August 2023 in medRxiv
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DDDev Desai
Dev Desai
ASAbhijay Shah
Abhijay Shah
HSHetvi Shah
Hetvi Shah
ANAarya A. Naik
Aarya A. Naik
Sharif Mohammed SadatSharif Mohammed Sadat
Sharif Mohammed Sadat
DRDwija Raval
Dwija Raval
Background This meta-analysis presents a comparison between Computed Tomography Pulmonary Angiography (CTPA) and Magnetic Resonance Angiography (MRA), to diagnose a pulmonary embolism. Computed tomography presents the advantage of imaging the entire thorax, facilitating the diagnosis of conditions that are commonly mistaken for pulmonary embolism, such as pneumonia, aortic dissection, and malignancy. UK and US guidelines have established CT amongst the basic investigations for pulmonary embolism. MRA does not require the use of ionizing radiation or iodinated contrast, thus making it possible for routine use of multiphasic acquisitions as well as for repeated contrast injections Methodology For the collection of the data, a search was done by two individuals using PubMed, Google Scholar, and Cochrane Library databases for all relevant literature. Full - Text Articles written only in English were considered. Each qualifying paper was independently evaluated by two reviewers. Each article was analyzed for the number of patients, their age, procedure modality, and incidence of the pre decided complications. Results The results also showed a high positive predictive value of 0.947 or 94.7% for MRA in the diagnosis of Pulmonary embolism, as compared with CTPA. Some analyses have marked MRA to have low specificity. These results establish MRA as a respectable alternative for diagnosis of APE, especially in cases when reducing radiation exposure is desired. However, the gold standard of diagnosis remains Computed Tomography Pulmonary Angiography. Conclusion As the results show, though MRA has high statistical value for the diagnosis of pulmonary embolism, it also has its drawbacks. MRA cannot be used in severely ill patients as it continues to be challenging, with the longer scan times and multiple breath holds that are required in different MR protocols are difficult to follow in these patients. CTPA remains the gold standard for diagnosis of Pulmonary embolism, with MRA as a secondary test used when CTPA is contraindicated.

12 February 2024 in Preprints.org
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Sharif Mohammed SadatSharif Mohammed Sadat
Sharif Mohammed Sadat
DDDev Desai
Dev Desai
MMMaria Eleni Malafi
Maria Eleni Malafi
Individuals with BPD grapple with unstable relationships, marked by extreme emotional swings and interpersonal conflicts. Emotional instability, a distorted self-image, and impulsivity further complicate matters, often leading to self-harm and suicide attempts as desperate coping mechanisms. Genetics and adverse childhood experiences contribute to BPD's development, shaping brain function and emotional regulation. Diagnosis involves meticulous assessments, paving the way for personalized treatments like dialectical behavior therapy and, in severe cases, hospitalization. Early intervention, professional support, and societal understanding are pivotal for positive outcomes, and challenging mental health stigma.