Involvement and lifestyle quality in terms of health are impacted by spinal cord injury. Spinal cord injury (SCI) patient sufferers deal with physical, social, and psychological repercussions. Annual spinal cord injuries are anticipated to range between 250,000 and 500,000. Clinical signs of SCI could include a partial or complete sensation loss and/or motor activity below the site of the damage. While quadriplegia could develop from injuries to the cervical region, paraplegia could result from injuries to the lower thorax. The most popular technique for predicting outcomes after the SCI is the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI), which was created in partnership with the American Spinal Injury Association. A 28-year-old patient visited our hospital with complaints of reduced strength in both lower limbs and unable to walk. For those with whole or incomplete paraplegia, regaining independent mobility during the chronic phase is the most crucial goal. Bed mobility training, upper limb strengthening, trunk control, and intervention were started. SCI is an example of a low-incidence ailment that does not generate sufficient market demand to sustain the development of specialist services in distant places. The rehabilitation strategy should include weight-bearing mat exercises, home exercise programs, and ambulation orthoses. Early physiotherapy participation on the side of the patient allowed him to avoid major secondary issues including bed sores and joint contractures. One of the crucial components of the recovery process for those with spinal cord injuries is physical therapy.

Guillain-Barré syndrome (GBS) is acute, ascending, immune-mediated, monophasic polyneuropathy, which manifests itself as a lower motor neuron lesion, which occurs mostly after a prior infection. It is autoimmune in origin and has an impact on the peripheral nervous system. GBS is usually not linked to an autoimmune or other systemic condition and is most frequently a post-infectious disorder that affects healthy patients. The symptoms of GBS, an acute immune-mediated polyradiculoneuropathy, include symmetrical limb weakness that worsens quickly and hypo- or areflexia. There may also be sensory complaints, involvement of cranial and autonomic nerve fibres, and frequent pain that will appear before weakening. Weakness, sensory loss, weariness, and discomfort are the most typical remaining deficiencies in an atypical variant of GBS. This case also describes the variant of atypical GBS. A 10-year-old girl was referred to the hospital with complaints of difficulty in swallowing, drooling of saliva, weakness of left upper and bilateral lower limbs, and fever for 10 days. There was no past history of travelling or infection. At the time of admission, the patient was on oxygen support for breathing and she was transferred to ICU immediately. Investigations were done such as a nerve conduction velocity test and complete blood count. Neuro-physiotherapy of the patient was started after 35 days of hospitalisation. With proper rehabilitation, the patient was able to gain strength and the ability to swallow food. The patient was able to resume her academic career.

Anaplastic astrocytoma is a kind of astrocytoma (a type of brain cancer) that is classified as World Health Organization (WHO) grade III. Headaches, poor mental status, focal neurological impairments, and seizures are the most prevalent early signs and symptoms of anaplastic astrocytoma. Anaplastic astrocytomas have also been linked to earlier exposure to vinyl chloride and large doses of brain radiation treatment. Anaplastic astrocytomas are a form of astrocytoma that also falls under the umbrella term of gliomas, which are tumors that develop from glial cells. This is because astrocytes are a kind of glial cell. As a result, anaplastic astrocytomas (grade III) are also known as "grade III gliomas" or "high-grade gliomas. In this case study, we present a case of a 35-year-old male who presented to our cancer hospital with complaints of weakness in the right upper and lower limbs for two years. He was then diagnosed with anaplastic astrocytoma, grade III. But after tumor resection, he developed right hemiplegia with involvement of the right upper extremity and lower extremity. This case study demonstrates how the neuro-physiotherapy rehabilitation protocol in the case of hemiplegia after brain tumor resection aids in improving motor function and functional independence. Physiotherapy treatment that is modulated according to the patient’s needs plays a vital role in improving the quality of life and helping to delay the worsening of symptoms, thereby helping to increase the life span of patients diagnosed with anaplastic astrocytoma grade III.

Duchenne muscular dystrophy (DMD) is a progressive disorder. It is the most typical X-linked muscular dystrophy in children. It primarily affects males and is characterized by motor delays, muscle weakness, respiratory impairment, and loss of ambulation. A case study of a nine-year-old male diagnosed with DMD is presented. The patient had difficulty walking since the age of four and had a proximal lower extremity weakness on both sides previously with a reduced range of motion (ROM). For the last 15 days, the patient is unable to walk and has hypotonia in both lower limbs. The diagnostic Gowers sign was positive. Balance and mobility were affected. Treatment of this patient is focused mostly on maintaining the range of motion (ROM), respiratory training, and balance.

Presenting a Magnetic Resonance Imaging (MRI) finding of a 7 years, 5-month old male who was brought to our rural hospital by his father with chief complaints of swelling over his right hand since birth. His father narrated that the swelling is increasing significantly and the child has tenderness over swelling. The child underwent an angioembolism 1 month ago and has been brought for re-embolism. Now sclerotherapy has been planned for the patient. The physiotherapist received a call for a decreased range of motion at the elbow joint. Another haemangioma is also found in the forearm. MRI findings (sagittal T1W, T2W, STIR/PD) noted an altered signal intensity oval lesion of size 5.4 x 5.6 x 6.2 cm appearing in the anterior intermuscular compartment and deep subcutaneous plane of the right arm displacing underlying muscles. Multiple prominent vascular channels are noted in the subcutaneous plane of the right arm. A similar signal with intensity was also noted in the intermuscular compartment of the proximal, a third of the right forearm. The prevalence of Arteriovenous Malformations (AVM) is 1 per 100,000 populations per year. The patient is undergoing medications and physiotherapy rehabilitation exercises. The physiotherapy protocol started early and is continuing. Early medication and rehabilitation is the way to recover the range of motion in such patients.