Angie Lizeth Buitrago Pabón

Mrs. Angie Lizeth Buitrago Pabón


Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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29 April 2024 in Microbiology Research
Verified
Journal Article
Open access
PDF file
APAngie Lizeth Buitrago Pabón
Angie Lizeth Buitrago Pabón
SRSalvador Ruiz
Salvador Ruiz
AAAlicia Jimenez Alberto
Alicia Jimenez Alberto
GAGerardo Aparicio-Ozores
Gerardo Aparicio-Ozores
JCJuan Castelan-Vega
Juan Castelan-Vega
RRRosa María Ribas-Aparicio
Rosa María Ribas-Aparicio
Zika virus (ZIKV) is an emerging flavivirus that represents significant public health challenges, particularly in the Americas, and is a substantial risk to other parts of the world due to its rapid expansion and its established association with neurological disorders, including Guillain–Barré syndrome and an intrauterine fetal infection that can cause microcephaly, blindness, and other congenital neurological complications. To date, no vaccine to prevent ZIKV infections has been approved. Therefore, developing a safe and effective vaccine against this virus is a global health priority. This review analyzes the ZIKV outbreaks, as well as associated neurological complications, its genome, and immunological responses. The current vaccines in development have reported results from preclinical and clinical trials about novel approaches to obtain safer and more effective vaccines and the challenges faced by ZIKV vaccine development.