Surgical site infection is a common and serious complication following abdominal surgery.
1 To prevent surgical site infection, it is essential to optimize perioperative conditions in the first hours following bacterial contamination.
2 Tissue oxygen tension is often low in wounds and colorectal anastomoses, and this may reduce tissue healing via oxidative killing by neutrophils and also reduce induction of collagen formation, neovascularization, and epithelialization.
3-7 Perioperative arterial and wound oxygen tension can be increased by a higher inspiratory oxygen fraction.
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