Domenico Spinelli

Dr. Domenico Spinelli


Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 December 2018 in Journal of Vascular Surgery
Verified
Journal Article
Closed access
DSDomenico Spinelli
Domenico Spinelli
FBFilippo Benedetto
Filippo Benedetto
RDRocco Donato
Rocco Donato
GPGabriele Piffaretti
Gabriele Piffaretti
MMMassimiliano M. Marrocco-Trischitta
Massimiliano M. Marrocco-Trischitta
STSanti Trimarchi
Santi Trimarchi

1 April 2017 in Annals of Vascular Surgery
Verified
Journal Article
Closed access
VCVito Cantisani
Vito Cantisani
EDEmanuele David
Emanuele David
DFDonatella Ferrari
Donatella Ferrari
FFFabrizio Fanelli
Fabrizio Fanelli
LMLuca Di Marzo
Luca Di Marzo
FDFerdinando D'Ambrosio
Ferdinando D'Ambrosio

16 October 2018 in Annals of Vascular Surgery
Verified
Journal Article
Closed access
PDF file
UBUmberto Bracale
Umberto Bracale
AGAnna Maria Giribono
Anna Maria Giribono
DSDomenico Spinelli
Domenico Spinelli
LGLuca Del Guercio
Luca Del Guercio
NPNarayana Pipitò
Narayana Pipitò
FBFilippo Benedetto
Filippo Benedetto

1 January 2023 in The Journal of Thoracic and Cardiovascular Surgery
Verified
Journal Article
Closed access
DSDomenico Spinelli
Domenico Spinelli
FWFred A. Weaver
Fred A. Weaver
AAAli Azizzadeh
Ali Azizzadeh
GMGregory A. Magee
Gregory A. Magee
GPGabriele Piffaretti
Gabriele Piffaretti
STSanti Trimarchi
Santi Trimarchi

1 November 2019 in The Journal of Cardiovascular Surgery
Verified
Journal Article
Closed access
DSDomenico Spinelli
Domenico Spinelli
SMStefania Marconi
Stefania Marconi
Rosario CarusoRosario Caruso
Rosario Caruso
MCMichele Conti
Michele Conti
FBFilippo Benedetto
Filippo Benedetto
STSanti Trimarchi
Santi Trimarchi
A geometrical understanding of the individual patient's disease morphology is crucial in aortic surgery. The aim of our study was to validate a questionnaire addressing understanding of aortic disease and use this questionnaire to investigate the value of 3D printing as a teaching tool for surgical trainees. Anonymized CT-angiography images of six different patients were selected as didactic cases of aortic disease and made into 3D models of transparent rigid resin with the Vat-photopolymerization technique. The 3D aortic models, which could be disassembled and reassembled, were displayed to 37 surgical trainees, immediately after a seminar on aortic disease. A questionnaire was developed to compare the trainees' understanding before (T0) and after (T1) demonstration of the 3D printed models. A panel of 15 experts participated in evaluating face and content validity of the questionnaire. The questionnaire validity was established and therefore the information investigated by the questionnaire could be synthetized using the mean of the items to indicate the understanding. The participants (mean age 28 years, range 26-34, male 59%) showed a significant improvement in understanding from T0 (median=7.25; IQR=1.50) to T1 (median=8.00; IQR=1.50; P=0.002). Preliminary data suggest that the use of 3D-printed aortic models as a teaching tool was feasible and improved the understanding of aortic disease among surgical trainees.

13 October 2016 in Journal of Vascular Surgery
Verified
Journal Article
Open access
PDF file
FBFilippo Benedetto
Filippo Benedetto
DSDomenico Spinelli
Domenico Spinelli
NPNarayana Pipitò
Narayana Pipitò
GGGiambattista Gagliardo
Giambattista Gagliardo
ANAlberto Noto
Alberto Noto
FSFrancesco Spinelli
Francesco Spinelli
The purpose of this study was to examine the outcomes of a vascular hybrid polytetrafluoroethylene (PTFE) graft, provided with a nitinol-reinforced section (NRS) on one end, in hemodialysis vascular access placement. A retrospective study was conducted including all the consecutive patients who underwent Gore Hybrid Vascular Graft (GHVG; W. L. Gore & Associates, Flagstaff, Ariz) implantation for hemodialysis access placement between October 2013 and November 2015. A propensity-matched control group was obtained from consecutive patients who underwent standard PTFE arteriovenous graft implantation between January 2010 and July 2013. The selection criteria were inadequate venous material for autogenous arteriovenous fistula placement, patent deep venous circulation, and vein diameter of 4 to 8.5 mm. The implantation technique involves the insertion of the NRS some centimeters into the target vein. Fluoroscopic guidance helps deploy the device in the desired landing zone (ie, position of the proximal end of the NRS), based on anatomic landmarks. Survival, functional patency rates, and complications were compared with a propensity-matched historical control group. Vein diameter, previous vascular access placement, and diabetes were tested as predictors of reintervention with a logistic regression analysis. There were 32 patients (14 men; mean age, 69 ± 14 years) who received the GHVG graft. The historical control group included 43 patients. Technical success was 100%. The graft configuration was brachial-axillary (n = 22 [69%]), brachial-basilic loop (n = 5 [16%]), brachial-antecubital loop (n = 3 [9%]), axilloaxillary loop (n = 1 [3%]), and femoral-femoral loop (n = 1 [3%]). Mean NRS oversize was 20% ± 7% (range, 3%-34%; median, 19%). Perioperative complications requiring revision included acute limb ischemia treated with thrombectomy (n = 1 [3%]) and graft infection requiring explantation (n = 2 [6%]). Two patients (6%) died in the hospital of unrelated causes. The mean follow-up was 15 ± 11 months (range, 0-33 months; median, 15.5). The propensity-matched groups included 25 patients each. Survival estimates at 24 months for the GHVG and standard PTFE groups were 91% ± 6% and 82% ± 9% (P > .05), respectively. The 12-month patency estimates were as follows: functional primary patency, 66% ± 10% vs 51% ± 10% (P > .05); functional assisted primary patency, 75% ± 9% vs 51% ± 10% (P > .05); and functional secondary patency, 79% ± 9% vs 67% ± 10% (P > .05). Reduction in vein diameter was associated with reintervention. The GHVG is a safe and effective alternative to standard PTFE in hemodialysis access surgery. Careful planning for the landing zone is advisable, especially for small outflow veins. Larger studies and randomized trials are needed to define the role for this device. A study including a greater number of centers experienced with this device is currently under way.