The rising burden of fungal infections presents a significant challenge to global healthcare, particularly with increasing antifungal resistance limiting treatment efficacy. Early detection and timely intervention remain critical, yet fungal pathogens employ diverse mechanisms to evade host immunity and develop resistance, undermining existing therapeutic options. Limited antifungal options and rising resistance necessitate novel treatment strategies. This review provides a comprehensive overview of conventional antifungal agents, their mechanisms of action, and emerging resistance pathways. Furthermore, it highlights recently approved and investigational antifungal compounds while evaluating innovative approaches such as nanotechnology, drug repurposing, and immunotherapy. Addressing antifungal resistance requires a multifaceted strategy that integrates novel therapeutics, enhanced diagnostic tools, and future research efforts to develop sustainable and effective treatment solutions.

The purpose of this study is to explore the relationship between premenstrual syndrome (PMS) and mindfulness as well as the mediating role of perceived social support (PSS) and health-related quality of life (HRQoL) among deaf/hard-of-hearing women. This is a cross-sectional study. An overall sample of 202 participants was selected. Path analysis was used. As indicated by the results obtained, PMS correlated significantly with mindfulness, PSS, and HRQoL. Moreover, mindfulness correlated significantly and positively with PSS and HRQoL. Besides, there is a significant negative relationship between PSS and HRQoL. PMS has direct effects on PSS and HRQoL. In addition, both PSS and HRQoL have immediate impacts on mindfulness. To conclude, this study examined and confirmed the relationship between PMS and mindfulness as mediated by PSS and HRQoL among deaf/hard-of-hearing women.

The purpose is to explore the relationship between Premenstrual Syndrome (PMS) and Mindfulness as well as the mediating role of Perceived Social Support (PSS) and health-related quality of Life (HRQoL) among deaf/hard-of-hearing women. This is a cross-sectional study. An overall sample of 202 participants was selected. Path analysis was used. As indicated by the results, PMS correlated significantly with Mindfulness, PSS and HRQoL. Moreover, Mindfulness correlated significantly and positively with PSS and HRQoL. Besides, there is a significant negative relationship between PSS and HRQoL. PMS has direct effects on PSS and HRQoL. In addition, both PSS and HRQoL have immediate impacts on Mindfulness. To conclude, this study examined and confirmed the relationship between PMS and Mindfulness as mediated by PSS and HRQoL among deaf/hard-of-hearing women.

The present study aimed to investigate the prevalence of premenstrual syndrome (PMS) and premenstrual dysphoric disorder among deaf/hard-of-hearing women with mood disorders in Saudi Arabia. The study sample comprised 380 deaf/hard-of-hearing women with mood disorders, and a convenient sampling method was used. For data analysis, descriptive statistics were used. Percentage, frequency and standard deviation, Chi-square test, unpaired t-test, one-way analysis of variance, and Pearson’s correlation were used for quantitative and statistical logistic regression analysis. According to the Premenstrual Syndrome Scale, the prevalence of PMS (moderate to severe PMS) is 71.05%, and the prevalence of premenstrual dysphoric disorders is 16%. Women with moderate to severe PMS consume more French fries/snacks, more processed food, more candy, and less banana than women with low to moderate PMS do. They also have food with high sodium quantity and food with high carbs. They have more physical disease and pain during this period. They suffer more than others from diarrhea and loose stools during menstruation. They use benzodiazepines more than women with low to moderate PMS do.