Recently, the area devoted to fractional calculus has given much attention by researchers. The reason behind such huge attention is the significant applications of the mentioned area in various disciplines. Different problems of real world processes have been investigated by using the concepts of fractional calculus and important and applicable outcomes were obtained. Because, there has been a lot of interest in fractional differential equations. It is brought on by both the extensive development of fractional calculus theory and its applications. The use of linear and quadratic perturbations of nonlinear differential equations in mathematical models of a variety of real-world problems has received a lot of interest. Therefore, motivated by the mentioned importance, this research work is devoted to analyze in detailed, a class of fractal hybrid fractional differential equation under Atangana- Baleanu- Caputo ABC derivative. The qualitative theory of the problem is examined by using tools of non-linear functional analysis. The Ulam-Hyer’s (U-H) type stability criteria is also applied to the consider problem. Further, the numerical solution of the model is developed by using powerful numerical technique. Lastly, the Wazewska-Czyzewska and Lasota Model, a well-known biological model, verifies the results. Several graphical representations by using different fractals fractional orders values are presented. The detailed discussion and explanations are given at the end.

This paper deals with the mathematical analysis of Tuberculosis by using fractal fractional operator. Mycobacterium TB is the bacteria that causes tuberculosis. This airborne illness mostly impacts the lungs but may extend to other body organs. When the infected individual coughs, sneezes or speaks, the bacterium gets released into the air and travels from one person to another. Five classes have been formulated to study the dynamics of this disease: susceptible class, infected of DS, infected of MDR, isolated class, and recovered class. To study the suggested fractal fractional model’s wellposedness associated with existence results, and boundedness of solutions. Further, the invariant region of the considered model, positive solutions, equilibrium point, and reproduction number. One would typically employ a fractional calculus approach to obtain numerical solutions for the fractional order Tuberculosis model using the Adams-Bashforth-Moulton method. The fractional order derivatives in the model can be approximated using appropriate numerical schemes designed for fractional order differential equations.

This research conducts a detailed analysis of a nonlinear mathematical model representing COVID-19, incorporating both environmental factors and social distancing measures. It thoroughly analyzes the model’s equilibrium points, computes the basic reproductive rate, and evaluates the stability of the model at disease-free and endemic equilibrium states, both locally and globally. Additionally, sensitivity analysis is carried out. The study develops a sophisticated stability theory, primarily focusing on the characteristics of the Volterra–Lyapunov (V–L) matrices method. To understand the dynamic behavior of COVID-19, numerical simulations are essential. For this purpose, the study employs a robust numerical technique known as the non-standard finite difference (NSFD) method, introduced by Mickens. Various results are visually presented through graphical representations across different parameter values to illustrate the impact of environmental factors and social distancing measures.