In contrast to conventional drug delivery systems, controlled drug release systems employ distinct methodologies. These systems facilitate the release of active substances in predetermined quantities and for specified durations. Polymer hydrogels have gained prominence in controlled drug delivery because of their unique swelling–shrinkage behavior and ability to regulate drug release. In this investigation, films with a hydrogel structure were crafted using polyvinyl alcohol, a biocompatible polymer, and silver nanoparticles. Following characterization, ibuprofen was loaded into the hydrogels to evaluate their drug release capacity. The particle sizes of silver nanoparticles synthesized using a green approach were determined. This study comprehensively examined the structural properties, morphological features, mechanical strength, and cumulative release patterns of the prepared films. In vitro cytotoxicity analysis was employed to assess the cell viability of drug-loaded hydrogel films, and their antibacterial effects were examined. The results indicated that hydrogel films containing 5% and 10% polyvinyl alcohol released 89% and 97% of the loaded drug, respectively, by day 14. The release kinetics fits the Korsmeyer–Peppas model. This study, which describes nanoparticle-enhanced polyvinyl alcohol hydrogel systems prepared through a cost-effective and environmentally friendly approach, is anticipated to contribute to the existing literature and serve as a foundational study for future research.

Ti6Al4V alaşımı mükemmel korozyon direnci, düşük yoğunluk, yüksek mekanik özellikler ve biyouyumluluk özellikleri nedeniyle ortodonti, medikal implant, cerrahi aletler, gıda ve havacılık endüstrisi gibi birçok alanda kullanılmaktadır. Özellikle biyomalzeme olarak kullanımı korozif ortamlara karşı mekanizmasının anlaşılmasını zorunlu kılmıştır. α+β alaşım gurubuna sahip Ti6Al4V alaşımının ısıl işlem sonrası birçok özelliği iyileştirilebilir. Bu çalışmada, Ti6Al4V alaşımına 1100°C sıcaklıkta 20 dak ısıl işlem uygulanarak su, hava ve yağ ortamlarında soğutulmuştur. Farklı soğutma ortamlarında işlem görmüş numunelerin SBF (yapay vücut sıvısı) ve Hank solüsyonlarına maruz kalması sonucu mikro yapıdaki faz dönüşümlerinin sertlik, yüzey kalitesi, işlenebilirlik ve korozyon özelliklerine etkileri incelenmiştir. Sonuçlara göre yüksek sıcaklıklarda oluşan ikincil fazların malzemenin mekanik ve korozyon özelliklerini etkilediği tespit edilmiştir. Soğutma ortamının ve korozif ortamın mekanik özellikler ve korozyon direnci üzerinde önemli bir etkiye sahip olduğu belirlenmiştir. Yağ ve havada gerçekleştirilen soğutma işlemi sonrasında her iki çözeltide de parçaların korozyon direncinin arttığı gözlemlenmiştir. Ayrıca işleme sonrası kesici uçlarda uç yüzeyinde kaplama ayrılması ve serbest yüzey aşınması tespit edilmiştir.

Egg white (EW) has emerged as a versatile natural biomaterial due to its wide availability, low cost, biodegradability, intrinsic bioactivity, and protein-derived gel- and film-forming capabilities. However, the existing literature has largely addressed EW-based biomaterials in terms of individual fabrication methods or specific applications, while comprehensive evaluations linking processing strategies to the resulting morphology, physicochemical properties, and biomedical functions remain limited. In this review, EW-based biomaterials are critically evaluated through an integrated processing, structure, property, and function framework encompassing molecular composition, fabrication strategies, morphological organization, physicochemical behavior, and biomedical performance. The molecular interactions and processing-dependent structural changes in major EW proteins, including ovalbumin, ovotransferrin, ovomucoid, ovomucin, and lysozyme, are discussed, and physical gelation, chemical and enzymatic crosslinking, chemical functionalization, and polymer/nanomaterial hybridization are compared as major fabrication approaches. These strategies enable the development of diverse morphologies, including hydrogels, nano/microparticles, films and membranes, micro/nanofibers, porous sponges, cryogels, and 3D-printed constructs, which provide distinct functional advantages in tissue engineering, 3D cell culture, wound healing, drug and bioactive molecule delivery, bioprinting, and biosensing. Particular emphasis is placed on the roles of crosslink density, porosity, swelling behavior, mechanical properties, degradation, and molecular transport in governing cellular responses and overall biomedical performance. Despite these advantages, batch-to-batch variability, the limited mechanical robustness of native protein networks, sterilization and storage constraints, and potential allergenicity and immunogenicity remain major barriers to clinical translation. Future research should therefore focus on standardized protein formulations, application-specific hybrid networks, advanced biofabrication approaches, and comprehensive long-term biosafety studies to enhance the translational potential of EW-based biomaterials.