Landslide mapping is the primary step for landslide investigation and prevention. At present, both the accuracy and the degree of automation of landslide mapping with remote sensing (LMRS) are still lower than those of general remote sensing classification. In order to improve the performance, previous attempts have been made to develop new features, classifiers, and rules, whereas few studies have investigated the in-depth causes and the corresponding solutions. In this paper, after reviewing the related literature, some of the fundamental difficulties hindering the improvement of LMRS are disclosed and discussed. Firstly, landslides do not have distinguishable spectral, spatial, or temporal characteristics, as they may actually be covered by other land covers. Secondly, the surface features of a landslide can vary greatly, affected by the different geological factors, geomorphological factors, hydrological factors, weather conditions, and other factors. Thirdly, the differences in the surface features are often remarkable and nonnegligible, and thus it is difficult to identify a landslide with only a few simple criteria. Finally, some solutions to the above difficulties are suggested. It is expected that the accuracy and applicability of LMRS could be greatly improved, by exploiting big data, utilizing the deep learning technique, and modelling the surface spatial structure of the landslide.

The medical image fusion is the process of coalescing multiple images from multiple imaging modalities to obtain a fused image with a large amount of information for increasing the clinical applicability of medical images. In this paper, we attempt to give an overview of multimodal medical image fusion methods, putting emphasis on the most recent advances in the domain based on (1) the current fusion methods, including based on deep learning, (2) imaging modalities of medical image fusion, and (3) performance analysis of medical image fusion on mainly data set. Finally, the conclusion of this paper is that the current multimodal medical image fusion research results are more significant and the development trend is on the rise but with many challenges in the research field.

In recent years, hundreds of Earth observation satellites have been launched to collect massive amounts of remote sensing images. However, the considerable cost and time to process the significant amount of data have become the greatest obstacle between data and knowledge. In order to accelerate the transformation from remote sensing images to urban thematic maps, a strategy to map the bare land automatically from Landsat imagery was developed and assessed in this study. First, a normalized difference bare land index (NBLI) was presented to maximally differentiate bare land from other land types in Wuhan City, China. Then, an unsupervised classifier was employed to extract the bare land from the NBLI image without training samples or self-assigned thresholds. Experimental results showed good performance on overall accuracy (92%), kappa coefficient (0.84), area ratio (1.1321), and match rate (83.96%), respectively. Results in multiple years disclosed that bare lands in the study site gradually moved from inner loops to the outer loops since 2007, in two main directions. This study demonstrated that the proposed method was an accurate and reliable option to extract the bare land, which led to a promising approach to mapping urban land use/land cover (LULC) automatically with simple indices.

Background: Long non-coding RNAs (lncRNAs) are related to human diseases by regulating gene expression. Identifying lncRNA-disease associations (LDAs) will contribute to diagnose, treatment, and prognosis of diseases. However, the identification of LDAs by the biological experiments is time-consuming, costly and inefficient. Therefore, the development of efficient and high-accuracy computational methods for predicting LDAs is of great significance. Results: In this paper, we propose a novel computational method (gGATLDA) to predict LDAs based on graph-level graph attention network. Firstly, we extract the enclosing subgraphs of each lncRNA-disease pair. Secondly, we construct the feature vectors by integrating lncRNA similarity and disease similarity as node attributes in subgraphs. Finally, we train a graph neural network (GNN) model by feeding the subgraphs and feature vectors to it, and use the trained GNN model to predict lncRNA-disease potential association scores. The experimental results show that our method can achieve higher area under the receiver operation characteristic curve (AUC), area under the precision recall curve (AUPR), accuracy and F1-Score than the state-of-the-art methods in five fold cross-validation. Case studies show that our method can effectively identify lncRNAs associated with breast cancer, gastric cancer, prostate cancer, and renal cancer. Conclusion: The experimental results indicate that our method is a useful approach for predicting potential LDAs.

Background: Classifying breast cancer subtypes is crucial for clinical diagnosis and treatment. However, the early symptoms of breast cancer may not be apparent. Rapid advances in high-throughput sequencing technology have led to generating large number of multi-omics biological data. Leveraging and integrating the available multi-omics data can effectively enhance the accuracy of identifying breast cancer subtypes. However, few efforts focus on identifying the associations of different omics data to predict the breast cancer subtypes.Results: In this paper, we propose a differential sparse canonical correlation analysis network (DSCCN) for classifying the breast cancer subtypes. DSCCN performs differential analysis on multi-omics expression data to identify differentially expressed (DE) genes and adopts sparse canonical correlation analysis (SCCA) to mine highly correlated features between multi-omics DE-genes. Meanwhile, DSCCN uses multi-task deep learning neural network separately to train the correlated DE-genes to predict breast cancer subtypes, which spontaneously tackle the data heterogeneity problem in integrating multi-omics data.Conclusions: The experimental results show that by mining the associations among multi-omics data, DSCCN is more capable of accurately classifying breast cancer subtypes than the existing methods.

Real social networks are huge and continue to expand rapidly. Most existing dynamic influence maximization (IM) algorithms are based on the node-to-node propagation model; hence, they have high time complexity and large storage space consumption. They usually reduce computational complexity using a sampling method while sacrificing the influence spread. In this paper, we propose a topic-aware community independent cascade (IC) model to reduce the complexity of dynamic IM without losing accuracy. The proposed model reduces the problem domain through community-level propagation, and then enhances the global features by integrating community structural features, community topic features, and time information into an IC model. We construct the data structure of the dynamic community index to avoid recalculation when the network grows. Based on the dynamic community index, we design a dynamic IM algorithm to quickly approximate the solution with the (1-1/e)-approximation guarantee. The experimental results on real social networks demonstrated that, compared with existing IM algorithms, the proposed algorithm had better stability and dynamic adaptability, higher computational efficiency, and less space consumption without reducing the approximation ratio and influence spread.