This study investigated the ecotoxicological impacts of environmentally relevant concentrations (0.05, 0.50, and 5.00 mg/L) of nickel nanoparticles (Ni-NPs) by assessing oxidative stress biomarkers. The worm Hediste diversicolor, the bivalve Mytilus spp., and the fish Sparus aurata were chronically exposed to Ni-NPs for 28 days, and glutathione S-transferases (GST), catalase (CAT), and thiobarbituric acid reactive substances (TBARS) levels were measured to evaluate biochemical responses. GST activity increased in H. diversicolor and the liver of S. aurata, suggesting a key role for this enzyme in Ni-NPs detoxification. CAT activity was inhibited in the digestive gland of Mytilus spp. at the highest Ni-NPs concentration, indicating possible disruption of antioxidant defense. TBARS levels rose significantly in the gills of Mytilus spp. exposed to high Ni-NP concentrations, suggesting oxidative damage beyond detoxification capacity. In contrast, TBARS decreased in the digestive gland of Mytilus and in H. diversicolor, possibly due to compensatory upstream antioxidant responses. These findings indicate that each species exhibits distinct adaptive responses to Ni-NP exposure. Overall, this study highlights the need to consider species- and tissue-specific responses when performing ecotoxicological risk assessments of nanomaterials.

(1) Background: Walnut consumption has been associated with having a positive effect on controlling and/or reducing the co-morbidities associated with cardiovascular disease (CVD). The effects of consuming walnuts of Portuguese origin on risk factors related to CVD were evaluated by measuring glucose, urea, TC, HDL-C, LDL-C, TG, AST, and ALT levels, anthropometric profiles, and blood pressure. (2) Methods: This trial study involved 24 volunteers, both female (n = 15) and male (n = 9), from Fernando Pessoa University, Porto. It consisted of a daily intake of 25 g of walnut kernels over a period of 45 days. Before and after intake, biochemical parameters, BMI and BP were measured. (3) Results: Despite the intake of nuts revealing a reduction in mean values of most of the parameters assessed, a significant drop was only observed in AST (p = 0.04).There was also a significant reduction in the mean values for Glu (p = 0.01), UR (p = 0.01) and HDL-C (p = 0.02) for women but not for men. (4) Conclusions: The dose and the period of intake were not effective in lowering the lipid profile but may have had a protective effect on liver function. The benefits were greater in women than in men.

Bioreaction engineering is fundamental to the optimization of biotechnological processes and the production of biochemicals by enzymes, microbial, plant and animal cells and higher organisms. A reference text for postgraduate students and researchers in biochemical engineering and bioreactor design, Multiphase Bioreactor Design describes the fundamentals of bioreactors and their increasingly complex varieties. It highlights new methodologies for the analysis of multiphase bioreactors, namely hydrodynamics, image analysis and modeling. Specific chapters also provide information on the interactions between kinetic and transport phenomena, biocatalyst stability and cell physiology in non-conventional media such as organic solvents and pressurized gas phases. Bioreaction engineering is fundamental to the optimization of biotechnological processes and the production of biochemicals by enzymes, microbial, plant and animal cells and higher organisms. A reference text for postgraduate students and researchers in biochemical engineering and bioreactor design, Multiphase Bioreactor Design describes the fundamentals of bioreactors and their increasingly complex varieties. It highlights new methodologies for the analysis of multiphase bioreactors, namely hydrodynamics, image analysis and modeling. Specific chapters also provide information on the interactions between kinetic and transport phenomena, biocatalyst stability and cell physiology in non-conventional media such as organic solvents and pressurized gas phases. Bioreaction engineering is fundamental to the optimization of biotechnological processes and the production of biochemicals by enzymes, microbial, plant and animal cells and higher organisms. A reference text for postgraduate students and researchers in biochemical engineering and bioreactor design, Multiphase Bioreactor Design describes the fundamentals of bioreactors and their increasingly complex varieties. It highlights new methodologies for the analysis of multiphase bioreactors, namely hydrodynamics, image analysis and modeling. Specific chapters also provide information on the interactions between kinetic and transport phenomena, biocatalyst stability and cell physiology in non-conventional media such as organic solvents and pressurized gas phases. Bioreaction engineering is fundamental to the optimization of biotechnological processes and the production of biochemicals by enzymes, microbial, plant and animal cells and higher organisms. A reference text for postgraduate students and researchers in biochemical engineering and bioreactor design, Multiphase Bioreactor Design describes the fundamentals of bioreactors and their increasingly complex varieties. It highlights new methodologies for the analysis of multiphase bioreactors, namely hydrodynamics, image analysis and modeling. Specific chapters also provide information on the interactions between kinetic and transport phenomena, biocatalyst stability and cell physiology in non-conventional media such as organic solvents and pressurized gas phases. Bioreaction engineering is fundamental to the optimization of biotechnological processes and the production of biochemicals by enzymes, microbial, plant and animal cells and higher organisms. A reference text for postgraduate students and researchers in biochemical engineering and bioreactor design, Multiphase Bioreactor Design describes the fundamentals of bioreactors and their increasingly complex varieties. It highlights new methodologies for the analysis of multiphase bioreactors, namely hydrodynamics, image analysis and modeling. Specific chapters also provide information on the interactions between kinetic and transport phenomena, biocatalyst stability and cell physiology in non-conventional media such as organic solvents and pressurized gas phases. Bioreaction engineering is fundamental to the optimization of biotechnological processes and the production of biochemicals by enzymes, microbial, plant and animal cells and higher organisms. A reference text for postgraduate students and researchers in biochemical engineering and bioreactor design, Multiphase Bioreactor Design describes the fundamentals of bioreactors and their increasingly complex varieties. It highlights new methodologies for the analysis of multiphase bioreactors, namely hydrodynamics, image analysis and modeling. Specific chapters also provide information on the interactions between kinetic and transport phenomena, biocatalyst stability and cell physiology in non-conventional media such as organic solvents and pressurized gas phases.