Corinne of GRANDJEAN

Mrs. Corinne of GRANDJEAN


Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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23 March 2024 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
CGCorinne of GRANDJEAN
Corinne of GRANDJEAN
GCGabriele Casso
Gabriele Casso
LNLeslie Noirez
Leslie Noirez
Manuel GranellManuel Granell
Manuel Granell
GSGeorges Louis Savoldelli
Georges Louis Savoldelli
PSPatrick Schoettker
Patrick Schoettker
A double-lumen tube or bronchial blocker positioning using flexible bronchoscopy for lung isolation and one-lung ventilation requires specific technical competencies. Training to acquire and retain such skills remains a challenge in thoracic anesthesia. Recent technological and innovative developments in the field of simulation have opened up exciting new horizons and possibilities. In this narrative review, we examine the latest development of existing training modalities while investigating, in particular, the use of emergent techniques such as virtual reality bronchoscopy simulation, virtual airway endoscopy, or the preoperative 3D printing of airways. The goal of this article is, therefore, to summarize the role of existing and future applications of training models/simulators and virtual reality simulators for training flexible bronchoscopy and lung isolation for thoracic anesthesia.

20 November 2025 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
OSOuanes Amine Ben Saad
Ouanes Amine Ben Saad
BRBenoit Rouiller
Benoit Rouiller
CGCorinne of GRANDJEAN
Corinne of GRANDJEAN
SGSina Grogg
Sina Grogg
JLJon Andri Lutz
Jon Andri Lutz
CMChloe Mimouni
Chloe Mimouni
Background: Although rarely performed, sternal resection for chondrosarcoma presents considerable anesthetic challenges, particularly in both immediate and long-term pain management. Method: This case study details the anesthetic protocol adopted for a 61-year-old male who underwent a sternal resection, chest wall reconstruction and muscle flap coverage due to chondrosarcoma. To optimize perioperative analgesia, a thoracic epidural catheter was placed preoperatively, combined intraoperatively with bilateral parasternal blocks targeting intercostal nerves at the resection margin. General anesthesia was tailored and paired with fluid restriction and minimal vasopressor doses to stabilize hemodynamics. Result: Postoperative recovery was marked by minimal discomfort, no need for systemic opioids, and early initiation of physiotherapy. At 12 months post-surgery, the absence of persistent pain or physical dysfunction suggested that the synergistic use of thoracic epidural and parasternal blocks offers effective control over both short-term and chronic pain following major chest wall surgery. The holistic integration of psychological support and an active rehabilitation regimen exemplified a biopsychosocial strategy, instrumental to the patient’s positive trajectory. Conclusions: This experience underscores the advantage of supplementing epidural anesthesia with parasternal nerve blocks in sternal resections, facilitating better outcomes and reducing systemic opioid use. Further studies involving broader patient populations are necessary to validate and refine this promising approach in preventing chronic pain in complex thoracic surgeries.

3 August 2026 in Preprints.org
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Preprint
Open access
PDF file
YTYong-Shun Thoo
Yong-Shun Thoo
MFMariana Fernandes
Mariana Fernandes
MDMaire-Joe Dib
Maire-Joe Dib
CGCorinne of GRANDJEAN
Corinne of GRANDJEAN
OSOuanes Amine Ben Saad
Ouanes Amine Ben Saad
Horner's syndrome is an uncommon but recognised complication of neuroaxial analgesia in obstetrics procedures, with an incidence of 0.4-4%. The incidence is significantly higher than in non-obstetric patients. This case report describes a 28-year-old primigravida who developed unilateral Horner's syndrome approximately one hour after lumbar epidural analgesia placement for labour pain relief. Upon examination the patient presented with left-sided ptosis, anisocoria, and unexpected sensory blockade extending to the T3-T4 lev-el, accompanied by localised numbness in the left breast and transient upper limb paraesthesia. The pathophysiology of Horner's syndrome involves cephalad spread of local anaesthetic toward the superior cervical sympathetic chain, disrupting sympathetic innervation to the ocular and facial areas. Primary and secondary damage to the sympathetic pathways in the central nervous offer a wide differential diagnosis. The management was conservative, including reduction of epidural bolus infusion rates and careful monitoring. The patient experienced complete resolution of all symptoms within five hours and delivered vaginally without complications. This case demonstrates the charac-teristically benign and self-limited nature of this complication, emphasising the importance of clinical awareness, proper reassurance of patients, and avoidance of unnecessary diagnostic testing.

28 August 2026 in Reports
Verified
Journal Article
Open access
PDF file
YTYong-Shun Thoo
Yong-Shun Thoo
MFMariana Fernandes
Mariana Fernandes
MDMarie-Joe Dib
Marie-Joe Dib
CGCorinne of GRANDJEAN
Corinne of GRANDJEAN
OSOuanes Amine Ben Saad
Ouanes Amine Ben Saad
Background and Clinical Significance: Horner’s syndrome is an uncommon but recognised complication of neuroaxial analgesia in obstetric procedures, with an incidence of 0.4–4%. Case Presentation: This case report describes a 28-year-old primigravida who developed unilateral Horner’s syndrome approximately one hour after lumbar epidural analgesia placement for labour pain relief. Upon examination the patient presented with left-sided ptosis, anisocoria, and unexpected sensory blockade extending to the T3–T4 level, accompanied by localised numbness in the left breast and transient upper limb paraesthesia. The pathophysiology of Horner’s syndrome involves cephalad spread of local anaesthetic toward the superior cervical sympathetic chain, disrupting sympathetic innervation to the ocular and facial areas. Primary and secondary damage to the sympathetic pathways in the central nervous offer a wide differential diagnosis. The management was conservative, including reduction in epidural bolus infusion rates and careful monitoring. The patient experienced complete resolution of all symptoms within five hours and delivered vaginally without complications. Conclusions: This case demonstrates the characteristically benign and self-limited nature of this complication, emphasising the importance of clinical awareness, proper reassurance of patients, and avoidance of unnecessary diagnostic testing.