Ultraviolet (UV) radiation has been demonstrated to cause skin disorders, including sunburn and relative symptoms of prolonged exposure. It has been reported that sunscreens have beneficial effects in reducing the incidence of skin disorders (sunburn, skin aging, and immunosuppression) through their ability to absorb, reflect, and scatter UV. Many commercial products have recently been manufactured from not only usual organic and inorganic UV filters, but also hybrid and botanical ingredients using typical formulations (emulsion, gel, aerosol, and stick). Particularly, these products have been supplemented with several preeminent properties to protect against the negative effects of not only UVB, but also UVA. However, the use of sunscreen has faced many challenges, including inducing photoallergic dermatitis, environment pollution, and deficiency of vitamin D production. Therefore, consumers should efficiently apply suitable products to improve sun protection. as well as to avoid the side effects of sunscreen.

This study investigated the effects of particulate matter (PM) on human skin diseases by conducting a systematic review of existing literature and performing a meta-analysis. It considered articles reporting an original effect of PM on human skin. From among 918 articles identified, 13 articles were included for further consideration after manual screening of the articles resulted in the exclusion of articles that did not contain data, review articles, editorials, and also articles in languages other than English. Random-effects models and forest plots were used to estimate the effect of PM on the skin by Meta-Disc analysis. According to people’s reports of exposure and negative skin effects (atopic dermatitis (AD), eczema, and skin aging, etc.) due to air pollution, the summary relative risk (odds ratio) of PM₁₀ was determined to be 0.99 (95% confidence interval (CI) 0.89–1.11) whereas PM_2.5 was determined to be 1.04 (95% CI 0.96–1.12). Simultaneously, there was a different extent of impact between PM₁₀ and PM_2.5 on atopic dermatitis (AD) for those of young age: the odds ratio of PM₁₀ and PM_2.5 were 0.96 (95% CI 0.83–1.11; I² = 62.7%) and 1.05 (95% CI 0.95–1.16; I² = 46%), respectively. Furthermore, the results suggest an estimated increase of disease incidence per 10 μg/m³ PM of 1.01% (0.08–2.05) due to PM₁₀ and 1.60% (0.45–2.82) due to PM_2.5. Following the results, PM₁₀ and PM_2.5 are associated with increased risks of human skin diseases, especially AD, whose risk is higher in infants and school children. With its smaller size and a high concentration of metals, PM_2.5 is more closely related to AD in younger people, compared to PM₁₀.

Bioactive peptides have gained significant attention in the cosmetic industry due to their potential in enhancing skin health and beauty. These small protein fragments exhibit various biological activities, such as antioxidant, anti-aging, anti-inflammatory, and antimicrobial activities, making them ideal ingredients for cosmetic formulations. These bioactive peptides are classified into four categories: signal, carrier, neurotransmitter-inhibitory, and enzyme-inhibitory peptides. This review provides insight into applying bioactive peptides in cosmetics and their mechanisms of action (e.g., downregulating pro-inflammatory cytokines, radical scavenging, inhibiting collagen, tyrosinase, and elastase synthesis). The abundant natural origins (e.g., animals, plants, and marine sources) have been identified as primary sources for extractions of cosmetic peptides through various techniques (e.g., enzymatic hydrolysis, ultrafiltration, fermentation, and high-performance liquid chromatography). Furthermore, the safety and regulatory aspects of using peptides in cosmetics are examined, including potential allergic reactions and regulatory guidelines. Finally, the challenges of peptides in cosmetics are discussed, emphasizing the need for further research to fully harness their potential in enhancing skin health. Overall, this review provides a comprehensive understanding of the application of peptides in cosmetics, shedding light on their transformative role in developing innovative and effective skincare products.

This study investigated the impact of residential radon exposure on human cancers (i.e., lung cancer and childhood leukemia) through a systematic review and meta-analysis of case–control studies. A total of 9724 articles obtained from electronic databases were assessed; however, only 55 case–control studies were eligible after manually screening and eliminating unnecessary studies. The causal associations were addressed by determining the meta-analysis’s estimated size effects (i.e., ORs/RRs) of the meta-analysis. Residential radon was revealed to significantly increase the incidence of lung cancer and childhood leukemia with pooled ORs of 1.38 [1.19; 1.60] (I² = 90%; p < 0.00001) and 1.43 [1.19; 1.72] (I² = 0% and p = 0.51), respectively. In addition, subgroup analyses were performed to reduce the heterogeneity of the initial meta-analyses. The results provided strong evidence that inhaling radon in the indoor environments is closely associated with the development of lung cancer and childhood leukemia in patients living in Europe and areas with high radon levels (≥100 Bq/m³).

Ribonucleic acid (RNA) viruses are one of the major classes of pathogens that cause human diseases. The conventional method to detect RNA viruses is real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR), but it has some limitations. It is expensive and time-consuming, with infrastructure and trained personnel requirements. Its high throughput requires sophisticated automation and large-scale infrastructure. Isothermal amplification methods have been explored as an alternative to address these challenges. These methods are rapid, user-friendly, low-cost, can be performed in less specialized settings, and are highly accurate for detecting RNA viruses. Microfluidic technology provides an ideal platform for performing virus diagnostic tests, including sample preparation, immunoassays, and nucleic acid-based assays. Among these techniques, nucleic acid isothermal amplification methods have been widely integrated with microfluidic platforms for RNA virus detection owing to their simplicity, sensitivity, selectivity, and short analysis time. This review summarizes some common isothermal amplification methods for RNA viruses. It also describes commercialized devices and kits that use isothermal amplification techniques for SARS-CoV-2 detection. Furthermore, the most recent applications of isothermal amplification-based microfluidic platforms for RNA virus detection are discussed in this article.

Plant extract-derived carbon dots (C-dots) have emerged as promising components for sustainability and natural inspiration to meet consumer demands. This review comprehensively explores the potential applications of C-dots derived from plant extracts in cosmetics. This paper discusses the synthesis methodologies for the generation of C-dots from plant precursors, including pyrolysis carbonization, chemical oxidation, hydrothermal, microwave-assisted, and ultrasonic methods. Plant extract-derived C-dots offer distinct advantages over conventional synthetic materials by taking advantage of the inherent properties of plants, such as antioxidant, anti-inflammatory, and UV protective properties. These outstanding properties are critical for novel cosmetic applications such as for controlling skin aging, the treatment of inflammatory skin conditions, and sunscreen. In conclusion, plant extract-derived C-dots combine cutting-edge nanotechnology and sustainable cosmetic innovation, presenting an opportunity to revolutionize the industry by offering enhanced properties while embracing eco-friendly practices.