Nicolaos Karatzas

Mr. Nicolaos Karatzas

orcid

Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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15 February 2023 in The American Journal of Sports Medicine
Verified
Journal Article
Open access
JCJason Corban
Jason Corban
NKNicolaos Karatzas
Nicolaos Karatzas
KZKevin Yan Zhao
Kevin Yan Zhao
ABAthanasios Babouras
Athanasios Babouras
SBStephane Bergeron
Stephane Bergeron
PMPaul A. Martineau
Paul A. Martineau
Background: Knee kinematic parameters during a drop vertical jump (DVJ) have been demonstrated to be associated with increased risk of noncontact anterior cruciate ligament (ACL) injury. However, standard motion analysis systems are not practical for routine screening. Affordable and practical motion sensor alternatives exist but require further validation in the context of ACL injury risk assessment. Purpose/Hypothesis: To prospectively study DVJ parameters as predictors of noncontact ACL injury in collegiate athletes using an affordable motion capture system (Kinect; Microsoft). We hypothesized that athletes who sustained noncontact ACL injury would have larger initial and peak contact coronal abduction angles and smaller peak flexion angles at the knee during a DVJ. Study Design: Case-control study; Level of evidence, 3. Methods: 102 participants were prospectively recruited from a collegiate varsity sports program. A total of 101 of the 102 athletes (99%) were followed for an entire season for noncontact ACL injury. Each athlete performed 3 DVJs, and the data were recorded using the motion capture system. Initial coronal, peak coronal, and peak sagittal angles of the knee were identified by our software. Results: Five of the 101 athletes sustained a noncontact ACL injury. Peak coronal angles were significantly greater and peak sagittal flexion angles were significantly smaller in ACL-injured athletes ( P = .049, P = .049, respectively). Receiver operating characteristic (ROC) analysis demonstrated an area under the curve of 0.88, 0.92, and 0.90 for initial coronal, peak coronal, and peak sagittal angle, respectively. An initial coronal angle cutoff of 2.96° demonstrated 80% sensitivity and 72% specificity, a peak coronal angle cutoff of 6.16° demonstrated 80% sensitivity and 72% specificity, and a peak sagittal flexion cutoff of 93.82° demonstrated 80% sensitivity and 74% specificity on the study cohort. Conclusion: Increased peak coronal angle and decreased peak sagittal angle during a DVJ were significantly associated with increased risk for noncontact ACL injury. Based on ROC analysis, initial coronal angle showed good prognostic ability, whereas peak coronal angle and peak sagittal flexion provided excellent prognostic ability. Affordable motion capture systems show promise as cost-effective and practical options for large-scale ACL injury risk screening.

5 June 2019 in PLOS ONE
Verified
Journal Article
Open access
PDF file
NKNicolaos Karatzas
Nicolaos Karatzas
TPTrevor Peter
Trevor Peter
SDSailly Dave
Sailly Dave
CFClare Fogarty
Clare Fogarty
NBNandi Belinsky
Nandi Belinsky
NPNitika Pant Pai
Nitika Pant Pai
The Joint United Nations Programme on HIV/AIDS (UNAIDS) Fast-Track initiative seeks to eliminate AIDS as a health threat by 2030, with its focus on UNAIDS 90-90-90 targets. Effective policies and programs, if scaled nationally, have the potential to generate a greater impact on HIV control, yet a synthesis of successful HIV policies/programs aligned to the targets is currently unavailable. To fill this gap, we conducted a systematic review to evaluate successful HIV policies and programs to direct future interventions. For the period 2007–2018, we searched 8 databases and classified eligible studies by country income level, UNAIDS targets, intervention type, and reported outcomes. Study outcomes were classified as per UNAIDS targets; proportionally: 90% target 1, 81% target 2, and 73% target 3. We retrieved 5201 citations and a final set of eight studies on policies. Break up by income: three (38%) from high income, one (12%) from middle income and four (50%) from low income. Break up by outcomes reported: 36% (4/11) focused on HIV testing, 46% (5/11) on antiretroviral therapy initiation, and 18% (2/11) on viral suppression. Across studies, UNAIDS targets were met in high-income countries, where policies and guidelines were adhered to, whereas in low and middle-income countries, non-adherence led to failure to reach the targets. Targets were also met when country infrastructure supported a targeted program and stakeholders were actively engaged. From the studies identified, we deduced a clear, positive correlation between implementation of policies and programs that resulted in an increase in patient awareness and an increase in partner notification with services that encouraged them, and together these resulted in increasing testing rates, and deployment of linkage/retention programs that improved retention in care. An analysis of these studies also suggests that policies, combined with the scale-up incentives, are needed to change the status quo. Incentives to improve the targets must exist; performance incentives at the health care worker level and country level incentives that could transform the nature of care. Given the complexity in reporting of targets, a one size fits all model is not a feasible option. However, the policies created a strong framework to shape future interventions.

20 March 2024 in Sensors
Verified
Journal Article
Open access
PDF file
NKNicolaos Karatzas
Nicolaos Karatzas
PAPatrik Abdelnour
Patrik Abdelnour
JCJason Philip Aaron Hiro Corban
Jason Philip Aaron Hiro Corban
KZKevin Yan Zhao
Kevin Yan Zhao
LOUIS-NICOLAS VEILLEUXLOUIS-NICOLAS VEILLEUX
LOUIS-NICOLAS VEILLEUX
PAPatrik Abdelnour
Patrik Abdelnour
Knee kinematics during a drop vertical jump, measured by the Kinect V2 (Microsoft, Redmond, WA, USA), have been shown to be associated with an increased risk of non-contact anterior cruciate ligament injury. The accuracy and reliability of the Microsoft Kinect V2 has yet to be assessed specifically for tracking the coronal and sagittal knee angles of the drop vertical jump. Eleven participants performed three drop vertical jumps that were recorded using both the Kinect V2 and a gold standard motion analysis system (Vicon, Los Angeles, CA, USA). The initial coronal, peak coronal, and peak sagittal angles of the left and right knees were measured by both systems simultaneously. Analysis of the data obtained by the Kinect V2 was performed by our software. The differences in the mean knee angles measured by the Kinect V2 and the Vicon system were non-significant for all parameters except for the peak sagittal angle of the right leg with a difference of 7.74 degrees and a p-value of 0.008. There was excellent agreement between the Kinect V2 and the Vicon system, with intraclass correlation coefficients consistently over 0.75 for all knee angles measured. Visual analysis revealed a moderate frame-to-frame variability for coronal angles measured by the Kinect V2. The Kinect V2 can be used to capture knee coronal and sagittal angles with sufficient accuracy during a drop vertical jump, suggesting that a Kinect-based portable motion analysis system is suitable to screen individuals for the risk of non-contact anterior cruciate ligament injury.

13 June 2024 in Sensors
Verified
Journal Article
Open access
PDF file
PAPatrik Abdelnour
Patrik Abdelnour
KZKevin Yan Zhao
Kevin Yan Zhao
ABAthanasios Babouras
Athanasios Babouras
JCJason Philip Aaron Hiro Corban
Jason Philip Aaron Hiro Corban
NKNicolaos Karatzas
Nicolaos Karatzas
PMPaul Andre Martineau
Paul Andre Martineau
Traditional motion analysis systems are impractical for widespread screening of non-contact anterior cruciate ligament (ACL) injury risk. The Kinect V2 has been identified as a portable and reliable alternative but was replaced by the Azure Kinect. We hypothesize that the Azure Kinect will assess drop vertical jump (DVJ) parameters associated with ACL injury risk with similar accuracy to its predecessor, the Kinect V2. Sixty-nine participants performed DVJs while being recorded by both the Azure Kinect and the Kinect V2 simultaneously. Our software analyzed the data to identify initial coronal, peak coronal, and peak sagittal knee angles. Agreement between the two systems was evaluated using the intraclass correlation coefficient (ICC). There was poor agreement between the Azure Kinect and the Kinect V2 for initial and peak coronal angles (ICC values ranging from 0.135 to 0.446), and moderate agreement for peak sagittal angles (ICC = 0.608, 0.655 for left and right knees, respectively). At this point in time, the Azure Kinect system is not a reliable successor to the Kinect V2 system for assessment of initial coronal, peak coronal, and peak sagittal angles during a DVJ, despite demonstrating superior tracking of continuous knee angles. Alternative motion analysis systems should be explored.

15 November 2024 in Orthopaedic Journal of Sports Medicine
Verified
Journal Article
Open access
KZKevin Yan Zhao
Kevin Yan Zhao
PAPatrik Abdelnour
Patrik Abdelnour
JCJason Philip Aaron Hiro Corban
Jason Philip Aaron Hiro Corban
NKNicolaos Karatzas
Nicolaos Karatzas
CLCameron Levins
Cameron Levins
PMPaul A. Martineau
Paul A. Martineau
Background: Anterior cruciate ligament (ACL) injuries are among the most distressing injuries for collegiate varsity athletes. Identifying easily attainable clinicodemographic risk factors in this subgroup can help screen for high-risk athletes who may benefit from proven ACL injury risk reduction programs. Purpose: To identify clinicodemographic risk factors for noncontact ACL injury among female and male collegiate varsity athletes from 10 different sports. Study Design: Cohort study; Level of evidence, 2. Methods: A total of 777 (276 female and 501 male athletes) collegiate varsity athletes from 3 consecutive seasons had an extended panel of clinicodemographic parameters recorded at their respective preseason physical sessions. The athletes were followed for 1 athletic season for noncontact ACL injuries. Results: Fifteen (6 female and 9 male athletes) athletes suffered a noncontact ACL injury during their season. Among all athletes, previous lower limb surgery and cutting sport participation were significantly associated with an increased risk of noncontact ACL injury. Among female athletes, previous ACL injury and previous lower limb surgery were significant risk factors. No significant clinicodemographic risk factors were identified in male athletes. Female sex was not a significant risk factor for noncontact ACL injury. Conclusion: The clinicodemographic risk factors for noncontact ACL injury identified in this study are easily attainable and may guide preseason screening for ACL injury risk in collegiate varsity athletes. The lack of association of these risk factors in male athletes may highlight the need to focus on other factors such as kinematics for these athletes.