Kodamaea ohmeri is an environmental yeast considered a rare emerging pathogen. In clinical settings, the correct identification of this yeast is relevant because some isolates are associated with resistance to antifungals. There is a lack of available data regarding the geographical distribution, virulence, and drug resistance profile of K. ohmeri. To contribute to the knowledge of this yeast, this study aimed to describe in depth three isolates of K. ohmeri associated with fungemia in Honduras. The identification of the isolates was carried out by sequencing the ribosomal ITS region. In addition, the susceptibility profile to antifungals was determined, and some properties associated with virulence were evaluated (exoenzyme production, biofilm formation, cell adhesion, and invasion). The isolates showed strong protease, phospholipase, and hemolysin activity, in addition to being biofilm producers. Adherence and invasion capacity were evident in the HeLa and Raw 264.7 cell lines, respectively. This study expands the understanding of the underlying biological traits associated with virulence in K. ohmeri, and it is the first report of the detection and identification of K. ohmeri in Honduras as a cause of human infection.

Kodamaea ohmeri is an environmental yeast considered a rare emerging pathogen. In clinical settings, the correct identification of this yeast is relevant since some isolates are associated with resistance to antifungals. There is a lack of available data regarding the geographical distribution, virulence, and drug resistance profile of K. ohmeri. To contribute to the knowledge of this yeast, this study aimed to describe in depth three isolates of K. ohmeri associated with fungemia in Honduras. The identification of the isolates was carried out by sequencing the ribosomal ITS region. In addition, the sensitivity profile to antifungals was determined, and some properties associated with virulence were evaluated (exoenzyme production, biofilm formation, cell adhesion, and invasion). The isolates showed strong protease, phospholipase, and hemolysin activity, in addition to being biofilm producers. Adherence and invasion capacity were evident in the HeLa and Raw 264.7 cell lines respectively. This study expands the understanding of the underlying biological traits associated with virulence in K. ohmeri and is the first report of the detection and identification of K. ohmeri in Honduras as a cause of human infection.

Journal of mycology and infection (Acronym: JMI, Abbreviation: J Mycol Infect) aims to publish articles of exceptional interests in the field of medical mycology. The journal originally was launched in 1996 as the Korean Journal of Medical Mycology and has reformed into the current state beginning on March of 2018. The contents of the journal should elucidate important microbiological fundamentals and provide qualitative insights to respective clinical aspects. JMI underlines the submission of novel findings and studies in clinical mycology that are enriched by analyses achieved through investigative methods.

Honduras is progressing toward malaria elimination as part of the Mesoamerican goal for 2030. As transmission declines, malaria increasingly occurs in focal outbreaks, particularly in geographically confined settings such as islands. Following an increase in cases beginning in 2024, the Bay Islands Department experienced continued outbreak transmission during 2025. This study characterized the genetic diversity and multilocus haplotype patterns of Plasmodium falciparum and P. vivax lineages circulating during this outbreak. Cases were confirmed by photo-induced electron transfer PCR (PET-PCR). Genetic diversity was assessed by Sanger sequencing of pfmsp1 for P. falciparum, and pvcsp and pvmsp3α for P. vivax; pfmdr1 was analysed separately as a drug-resistance marker. Diversity indices and multilocus profiles were analysed using DnaSP. Forty-nine samples were analysed: 18 P. falciparum and 31 P. vivax infections from three municipalities. All P. falciparum isolates carried a single pfmsp1 haplotype of the K1 allelic family. In P. vivax, two concordant multilocus haplotypes were detected: A/A predominated, whereas B/B was observed in five samples, mainly early in the outbreak. The outbreak showed marked P. falciparum homogeneity and restricted P. vivax multilocus diversity, consistent with focal amplification of limited parasite lineages. However, multiple introductions of genetically similar parasites cannot be excluded.