The escalating global prevalence of obesity underscores the need for effective and sustainable nutritional interventions. Functional foods, especially white kidney beans (Phaseolus vulgaris), show a promising avenue to link fundamental biochemical insights with clinically feasible interventions, supporting their potential as an adjunct dietary strategy for managing and preventing obesity. This review critically examines the mechanistic roles of white kidney bean in weight regulation, which includes suppression of starch digestion, attenuation of postprandial glycemia, modulation of appetite and satiety, and hypolipidemic effects. Clinical and preclinical evidence supports the potential of white kidney bean as a nutraceutical for metabolic health, demonstrating consistent reductions in body fat mass, glycemic excursion, and overall weight. Nevertheless, significant limitations persist, including heterogeneity in trial designs, absence of dose standardization, and inadequate long-term safety assessments. Furthermore, this review addresses food fortification, advancements in supplement formulation, and cooking techniques that enhance both consumer acceptability and the bioactivity of white kidney bean (WKB), along with the significance of regulatory standards to ensure safety and quality. Future research should integrate clinical, molecular and food technology methods to improve the translation of experimental findings into precision nutritional strategies for obesity management.
22 November 2024 in Journal of Innovative Research
Amber glass is widely used to pack a large number of industrial products. However, its waste is disposed of into landfills, which results in serious environmental concerns, and only a small amount of it is either reused or recycled. Recycling the glass offers reduction in the landfills and hence minimizes the adverse environmental impact. This study follows the concept of recycling amber glass to produce glass foam that possesses high strength. The hard glass foam is produced by sintering pulverized pharmaceutical amber glass and chicken bones at 860˚C and 10 min. Chicken bones were used for the first time as a recycling material for producing glass foam. In this work different characterization techniques were used to investigate the mechanical and structural properties of the produced glass foam. The glass foam produced resulted into high values of flexural strength ranging from 15.90 ± 2.34 to 28.31 ± 1.62 MPa. The prepared glass foam, due to its unique properties such as high strength, sound absorption, heat insulation and shock-wave absorption, offers valuable insights into the world of material science.
15 June 2025 in American Journal of Chemistry and Pharmacy
Amyloid beta oligomers play a key role in the pathophysiology of Alzheimer’s disease. Since it contributes to memory and neuronal loss, cognitive decline, degradation of neurons as well as diseases progression. As Aβ oligomer is very small and heterogeneous and it can change from one shape to another shape therefore it has various kinds of morphologies including monomers, oligomers and fibrils. Due to instable behavior of these proteins, it’s very difficult to understand its exact mechanism. In this concise review, information over the past seven years concentrated on the molecular characteristics of amyloid-β oligomers has been summarized along with two pathways involving protein aggregation and condensation. Furthermore, metal complexes, immunotherapies, and anti-Aβ antibodies are reported here, which can modulate aggregation, stabilize non-toxic forms, and enhance degradation. Finally, new discoveries on small molecules that control, modify and inhibit the progression of amyloid-β oligomers are integrated, as these are key characteristics of Alzheimer’s disease.