Danielle Nascimento Silva

Dr. Danielle Nascimento Silva

orcid

Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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5 December 2017 in PLOS ONE
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Journal Article
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DSDanielle Nascimento Silva
Danielle Nascimento Silva
AOArianne Pontes Oriá
Arianne Pontes Oriá
NANayone Lantyer Araujo
Nayone Lantyer Araujo
EMEmanoel Martins-Filho
Emanoel Martins-Filho
CMCaterina Muramoto
Caterina Muramoto
ALAlessandra Lima
Alessandra Lima
The objective of this study was to describe the anatomic and histologic features of the Sapajus sp. eye, comparing similarities and differences of humans and other species of non-human primates for biomedical research purposes. Computed tomography (CT) of adnexa, eye and orbit live animal, as well as formolized pieces of the same structures of Sapajus sp. for anatomical and histological study were also performed. The anatomical description of the eye and adnexa was performed using the techniques of topographic dissection and exenteration. Histological fragments were fixated in buffered formalin 10%, processed by the routine paraffin inclusion technique, stained with hematoxylin-eosin and special stains. CT scan evaluation showed no differences between the live animal and the formolized head on identification of visual apparatus structures. Anatomic and histologic evaluation revealed rounded orbit, absence of the supraorbital foramen and frontal notch, little exposure of the sclera, with slight pigmentation of the exposed area and marked pigmentation at the sclerocorneal junction. Masson's Trichrome revealed the Meibomian glands, the corneal epithelium and Bowman's membrane; in the choroid, melanocytes and Bruch's membrane were observed; and in the retina, cones and rods as well as, optic nerve, the lamina cribrosa of the nerve fibers bundles. Toluidine blue highlighted the membranes: Bowman, Descemet and the endothelium; in the choroid: melanocytes; and in the retina: nuclear layers and retinal pigment epithelium. In view of the observed results Sapajus sp. is an important experimental model for research in the ophthalmology field, which has been shown due to the high similarity of its anatomical and histological structures with the human species.

8 May 2024 in Veterinary Research Communications
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RSRoseclea Chagas dos Santos
Roseclea Chagas dos Santos
ALAlessandra Lima
Alessandra Lima
WDWashington LC dos-Santos
Washington LC dos-Santos
AOArianne Pontes Oriá
Arianne Pontes Oriá
RGRafaela de Sousa Gonçalves
Rafaela de Sousa Gonçalves
SBStella Maria Barrouin-Melo
Stella Maria Barrouin-Melo

20 June 2022 in Parasitology Research
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ESElainne Maria Beanes da Silva Santos
Elainne Maria Beanes da Silva Santos
DSDanielle Nascimento Silva
Danielle Nascimento Silva
WPWendell Marcelo De Souza Perinotto
Wendell Marcelo De Souza Perinotto
GMGustavo Rodamilans de Macedo
Gustavo Rodamilans de Macedo
TPThaís Torres Pires
Thaís Torres Pires
ALAlessandra Lima
Alessandra Lima

10 November 2025 in Veterinary Ophthalmology
Verified
Journal Article
Open access
DSDanielle Nascimento Silva
Danielle Nascimento Silva
JCJOSE LUIZ CATÃO-DIAS
JOSE LUIZ CATÃO-DIAS
WPWendell Marcelo De Souza Perinotto
Wendell Marcelo De Souza Perinotto
MMMatheus Vilardo Loés Moreira
Matheus Vilardo Loés Moreira
NLNayone Lantyer‐Araujo
Nayone Lantyer‐Araujo
ALAlessandra Lima
Alessandra Lima
Objective: This study aimed to identify and report ophthalmic and adnexal diseases found in specimens of the Green sea turtle ( Chelonia mydas ). Animal Studied and Procedures: Thirty‐nine animals stranded on the beaches of the north coast of Bahia, Brazil were submitted to necropsy. A total of 158 samples of the visual system (eyelids, eyes, and salt glands) from females (71.8%; 28/39) and males (28.2%; 11/39) were analyzed. Results: Samples without macro and microscopic changes counted as 30.4% (48/158) of the evaluated samples. Approximately 69.6% (110/158) had ophthalmic lesions; 92 were bilateral (24 eyelids, 44 eyes, and 24 salt glands), and 18 were unilateral. The anatomopathological evaluation of the specimens revealed predominantly neoplastic and inflammatory lesions, with fibropapillomatosis (FP) being the most frequent finding (58.9%; 93/158), followed by spirorchidiasis (46.8%; 74/158). Other ophthalmic lesions included mucopurulent conjunctivitis, ulcerative keratitis, corneal perforation, panophthalmitis, phthisis bulbi, bilateral scar tissue in the eyelids, and lithiasis in the salt glands. Conclusion: This study highlights the significance of understanding eye diseases as they can directly impact the management and preservation of sea turtles. This is particularly true for species in which the visual system plays a crucial role in feeding and migration. Therefore, this data can assist in promoting and implementing preventive and therapeutic measures for the conservation of these animals.